5433-06-7

Usage

Uses

Used in Pharmaceutical Industry:
1-(carboxymethyl)-4-methylcyclohexanecarboxylic acid is used as a building block for the synthesis of various drugs and pharmaceutical intermediates due to its unique structure and carboxylic acid functionality.
Used in Chemical Industry:
1-(carboxymethyl)-4-methylcyclohexanecarboxylic acid is used as a versatile component in organic synthesis to create complex molecules with specific properties, contributing to advancements in materials science.
Further research and development of 1-(carboxymethyl)-4-methylcyclohexanecarboxylic acid's potential applications could lead to significant advancements in drug development and materials science, expanding its uses in various industries.

Upstream product

• 859937-32-9 8-methyl-2-oxa-spiro[4.5]decan-3-one 
• 85179-91-5 4-methylcyclohexane-1,1-diacetic acid 
• 57093-77-3 cyano-(4-methyl-cyclohexylidene)-acetic acid ethyl ester 
• 589-92-4 1-methylcyclohexan-4-one 
• 10035-10-6 hydrogen bromide 
• 872276-51-2 2-oxo-2,2'-(4-methyl-cyclohexylidene)-di-acetic acid 
• 7722-84-1 dihydrogen peroxide 
• 7647-01-0 hydrogenchloride 
• 71980-90-0 ethyl (1-cyano-4-methylcyclohex-1-yl)cyanoacetate 
• 7732-18-5 water 
• 85179-90-4 (1-carboxy-4-methyl-cyclohexyl)-acetic acid-anhydride 
• 623-11-0 1-methyl-4-nitrosobenzene 

Downstream Products

• 81831-43-8 1-Methoxycarbonylmethyl-4-methyl-cyclohexanecarboxylic acid methyl ester 
• 81831-44-9 1-Methoxycarbonylmethyl-4-methyl-cyclohexanecarboxylic acid methyl ester 
• 936109-03-4 C₁₆H₂₀N₂O₂ 
• 936109-04-5 N-[(4-methylphenyl)-amino]-7-methyl-2-azaspiro[4.5]decane-1,3-dione 
• 936109-05-6 C₁₆H₁₈Cl₂N₂O₂ 
• 93159-27-4 4-methyl-1-phenacyl-cyclohexanecarboxylic acid 
• 93163-27-0 4-methyl-1-phenethyl-cyclohexanecarboxylic acid 

Relevant academic research and scientific papers

Evaluation of various N-substituted azaspiranedione derivatives as potential antimicrobial agents

A series of N-substituted hydrazines were condensed with various spiro[4,5] and [5,5]anhydrides and the resultant N-substituted azaspiranediones were evaluated for antimicrobial activity. None displayed any significant activity in a variety of organisms tested.

Stereochemistry of 1,4-Addition of Nucleophiles to Ethyl Cyclohexylidenecyanoacetates

The stereochemistry of 1,4-addition of several nucleophiles such as cyanide, sodium borohydride, and methylmagnesium iodide to three substituted ethyl cyclohexylidenecyanoacetates (1-3) has been determined.A higher preference for equatorial attack is observed in these compounds than in related cyclohexanones, which is considerably diminished by the use of aprotic polar solvents.The results do not show any appreciable contribution of product stability control, recently shown to be important for hydride reduction of cyclohexanones, and have been rationalized on thebasis of a six-center cyclic transition state in which steric factors play a dominant role.These compounds have also been reduced by catalytic hydrogenation (Pd/C), and, interestingly, with unhindered systems (1, 2) hydrogenation takes place more from the axial side (40-60percent) as compared to cyclohexanones.