5439-08-7

Usage

Uses

Used in Agrochemical Industry:
Methyl 3,5-dichloropicolinate is used as a key ingredient in the formulation of herbicides for controlling weeds in various crops. Its herbicidal properties make it an effective solution for agricultural applications.
Used in Pharmaceutical Industry:
Methyl 3,5-dichloropicolinate is also utilized in the production of pharmaceuticals due to its potential medicinal properties. Its use in this industry highlights its versatility and importance in different sectors.
It is crucial to handle Methyl 3,5-dichloropicolinate with care, as it can be hazardous to human health and the environment if not properly managed.

InChI:InChI=1/C7H5Cl2NO2/c1-12-7(11)6-5(9)2-4(8)3-10-6/h2-3H,1H3

Upstream product

• 67-56-1 methanol 
• 70151-22-3 methyl 3,5-dichloropicolinic acid chloride 
• 81719-53-1 3,5-dichloropyridine-2-carboxylic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 200711-45-1 3,4,5-trichloro-pyridine-2-carboxylic acid methyl ester 
• 5439-04-3 3,4,5-trichloropicolinic acid 
• 846045-08-7 3,5-dichloro-4-hydroxy-pyridine-2-carboxylic acid 

Downstream Products

• 5468-71-3 3,5-dichloropicolinamide 
• 1202250-84-7 3-chloro-5-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid methyl ester 
• 1202250-85-8 3,5-bis-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid methyl ester 
• 1202250-86-9 5-chloro-3-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid methyl ester 
• 1344675-56-4 C₁₈H₂₅ClN₄O₃ 
• 1344675-05-3 C₂₄H₃₁N₅O₄ 

Relevant academic research and scientific papers

Preparation method of vadadustat

The invention provides a preparation method of vadadustat, and belongs to the field of pharmaceutical chemical industry. The method comprises the following steps: mixing 3,5-dichloro-2-picolinic acid,methanol and sulfuric acid at a certain temperature, and carrying out a reaction to obtain 3,5-dichloro-2-picolinic acid methyl ester; adding 3-chlorophenylboronic acid, and carrying out a catalyticreaction to obtain 5-(3-chlorphenyl)-3-chloropyridine-methyl formate; and adding glycine into the 5-(3-chlorphenyl)-3-chloropyridine-methyl formate, and carrying out a reaction to obtain the 5-(3-chlorphenyl)-3-chloropyridine-methyl formate. The method has the characteristics of high product purity, high yield, low cost, simple operation and stable process.

TRICYCLIC COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS

The present invention provides compounds of Formula (A): (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent, and methods of using the compositions and combinations to treat conditions including cancers.

FAAH INHIBITORS

The present disclosure relates to compounds useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the com

NOVEL HETEROARYL CARBOXAMIDE DERIVATIVES

The invention is concerned with novel heteroaryl carboxamide derivatives of formula (I), wherein m, X, Y, R1, R2, R3 and R4 are as defined in the description and in the claims, as well as physiologically accepta