5444-75-7Relevant articles and documents
Esterification of Tertiary Amides by Alcohols Through C?N Bond Cleavage over CeO2
Toyao, Takashi,Nurnobi Rashed, Md.,Morita, Yoshitsugu,Kamachi, Takashi,Hakim Siddiki,Ali, Md. A.,Touchy,Kon, Kenichi,Maeno, Zen,Yoshizawa, Kazunari,Shimizu, Ken-ichi
, p. 449 - 456 (2018/09/11)
CeO2 has been found to promote ester forming alcoholysis reactions of tertiary amides. The present catalytic system is operationally simple, recyclable, and it does not require additives. The esterification process displays a wide substrate scope (>45 examples; up to 93 % isolated yield). Results of a density functional theory (DFT) study combined with in situ FT-IR observations indicate that the process proceeds through rate limiting addition of a CeO2 lattice oxygen to the carbonyl group of the adsorbed acetamide species with energy barrier of 17.0 kcal/mol. This value matches well with experimental value (17.9 kcal/mol) obtained from analysis of the Arrhenius plot. Further studies by in situ FT-IR and temperature programmed desorption using probe molecules demonstrate that both acidic and basic properties are important, and consequently, CeO2 showed the best performance for the C?N bond cleavage reaction.
Nucleophilic Substitutions of Alcohols in High Levels of Catalytic Efficiency
Stach, Tanja,Dr?ger, Julia,Huy, Peter H.
supporting information, p. 2980 - 2983 (2018/05/28)
A practical method for the nucleophilic substitution (SN) of alcohols furnishing alkyl chlorides, bromides, and iodides under stereochemical inversion in high catalytic efficacy is introduced. The fusion of diethylcyclopropenone as a simple Lewis base organocatalyst and benzoyl chloride as a reagent allows notable turnover numbers up to 100. Moreover, the use of plain acetyl chloride as a stoichiometric promotor in an invertive SN-type transformation is demonstrated for the first time. The operationally straightforward protocol exhibits high levels of stereoselectivity and scalability and tolerates a variety of functional groups.
Method for preparing colorless and transparent ethylhexyl benzoate
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Paragraph 0014; 0015; 0028, (2017/03/28)
The invention discloses a method for preparing ethylhexyl benzoate. The method includes particular steps of continuously carrying out reaction on benzoic acid and 2-ethyl hexanol under the effects of catalysts at the reaction temperature of 140-150 DEG C under the control for 5-15 hours to obtain reaction products; adding alkali liquid into the reaction products and regulating a pH (potential of hydrogen) value of the reaction products until the reaction products are neutral; washing the reaction products by the aid of pure water and sodium sulfate; layering the reaction products and acquiring oil layers to obtain the ethylhexyl benzoate. The method has the advantages that reaction conditions are mild, and the method is convenient to implement and low in corrosiveness on equipment; the method is high in yield, and the ethylhexyl benzoate prepared by the aid of the method is colorless, clear and transparent.
