5461-51-8

Basic information

• Product Name: N-phenyl-N-(propan-2-yl)acetamide
• Synonyms: acetamide, N-(1-methylethyl)-N-phenyl-; N-(1-methylethyl)-N-phenylacetamide; N-isopropylacetanilide
• CAS NO: 5461-51-8
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.2429
• Mol File: 5461-51-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 257.1°C at 760 mmHg
• Flash Point: 105.3°C
• Density: 1.016g/cm³
• Vapor Pressure: 0.0148mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: N-phenyl-N-(propan-2-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-N-(propan-2-yl)acetamide(5461-51-8)
• EPA Substance Registry System: N-phenyl-N-(propan-2-yl)acetamide(5461-51-8)

Safety Data

• Hazardous Substances Data: 5461-51-8(Hazardous Substances Data)

Upstream product

• 926-06-7 isopropyl methanesulfonate 
• 103-84-4 Acetanilid 
• 1918-16-7 2-chloro-N-(1-methylethyl)-N-phenylacetamide 
• 102-97-6 Benzyl-isopropyl-amin 
• 507-09-5 tiolacetic acid 
• 768-52-5 N-Isopropylaniline 
• 4232-27-3 2,4-dinitrophenyl acetate 
• 62-53-3 aniline 
• 75-26-3 isopropyl bromide 

Downstream Products

• 768-52-5 N-Isopropylaniline 
• 54813-77-3 N-ethyl-N-isopropylaniline 
• 65957-07-5 N-isopropyl-N’-methyl-N,N'-diphenylethene-1,1-diamine 
• 53171-85-0 acetic acid-(N-isopropyl-4-nitro-anilide) 

Relevant articles and documents

Hydrodehalogenation of Aryl Halides through Direct Electrolysis

A catalyst- and metal-free electrochemical hydrodehalogenation of aryl halides is disclosed. Our reaction by a flexible protocol is operated in an undivided cell equipped with an inexpensive graphite rod anode and cathode. Trialkylamines nBu3N/Et3N behave as effective reductants and hydrogen atom donors for this electrochemical reductive reaction. Various aryl and heteroaryl bromides worked effectively. The typically less reactive aryl chlorides and fluorides can also be smoothly converted. The utility of our method is demonstrated by detoxification of harmful pesticides and hydrodebromination of a dibrominated biphenyl (analogues of flame-retardants) in gram scale.

ELECTROREDUCTIVE N-ALKYLATION OF AMIDES, CARBAMATES, AND N-HETEROCYCLES

The N-alkylation of amides, lactams, carbamates, and N-heterocycles was easily attained in good yields by the electroreduction of the substrates in the presence of alkyl halides.