5661-14-3

Basic information

• Product Name: N-(benzenesulfonyl)acetamide
• Synonyms: N-(benzenesulfonyl)acetamide
• CAS NO: 5661-14-3
• Molecular Formula: C₈H₉NO₃S
• Molecular Weight: 199.23
• Mol File: 5661-14-3.mol
• Article Data: 30

Chemical Properties

• Melting Point: 126 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.296g/cm³
• Refractive Index: 1.545
• PKA: 5.51±0.10(Predicted)
• CAS DataBase Reference: N-(benzenesulfonyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzenesulfonyl)acetamide(5661-14-3)
• EPA Substance Registry System: N-(benzenesulfonyl)acetamide(5661-14-3)

Safety Data

• Hazardous Substances Data: 5661-14-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H9NO3S/c1-7(10)9-13(11,12)8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)

Upstream product

• 64-19-7 acetic acid 
• 33912-13-9 benzenesulfonyl-imidosulfurous acid dichloride 
• 98-10-2 benzenesulfonamide 
• 1363906-80-2 1-acetyl-2,3,4,6,7,8-hexahydropyrrolo[1,2-a]pyrimidinium tetraphenylborate 
• 98-09-9 benzenesulfonyl chloride 
• 141-78-6 ethyl acetate 
• 88513-27-3 N-Phenylsulfonyl-iminoschwefligsaeure-bis-<4-nitro-phenylester> 
• 110-86-1 pyridine 
• 10039-63-1 S-cyclohexyl ethanethioate 
• 7732-18-5 water 
• 107046-13-9 4-nitrophenyl N-acetylbenzeneiminosulfonate 
• 13435-12-6 N-Trimethylsilylacetamide 
• 143105-03-7 N-acetyl-2-chlorobenzenesulfonamide 
• 75-36-5 acetyl chloride 

Downstream Products

• 5339-67-3 N-ethylbenzenesulfonamide 
• 860743-29-9 N-benzenesulfonyl-acetimidoyl chloride 
• 1620220-82-7 C₁₂H₁₃NO₄S 
• 3306-62-5 2-AMINOBENZENESULFONAMIDE 
• 13493-50-0 4-hydroxybenzaldehyde benzenesulfonate ester 
• 98-10-2 benzenesulfonamide 

Relevant articles and documents

O-Trimethylsilyl-N-phenylsulfonylacetimidate: Synthesis and Structure

Abstract: A method for silylation of N-acetylbenzenesulfonamide has been proposed. The structural features of the obtained O-trimethylsilyl-N-phenylsulfonylacetimidate have been studied by means of NMR and IR spectroscopy as well as single-crystal X-ray d

Alkene Carboarylation through Catalyst-Free, Visible Light-Mediated Smiles Rearrangement

A light-mediated Truce–Smiles arylative rearrangement is described that proceeds in the absence of any photocatalyst. The protocol creates two C?C bonds from simple starting materials, with the installation of an aryl ring and a difluoroacetate moiety across unactivated alkenes. The reaction proceeds via a radical mechanism, utilizing a light-mediated reduction of ethyl bromodifluoroacetate by N,N,N′,N′-tetramethylethylenediamine (TMEDA) to set up intermolecular addition to an unactivated alkene, followed by Truce–Smiles rearrangement.

Iridium-Catalyzed ortho-C?H Amidation of Benzenesulfonamides with Sulfonyl Azides

We developed herein an iridium-catalyzed direct C?H activation/ C?N bond formation reaction of benzenesulfonamides with sulfonyl azides. The amidation reaction provides a protocol for the synthesis of 2-aminobenzesulfonamides in good to excellent yields. This strategy features a wide substrate scope, tolerates a broad range of functional groups under external oxidant-free conditions and only releases molecular nitrogen as the sole by-product. Moreover, the preliminary mechanism was investigated and the proposed reaction pathway was provided. (Figure presented.).