56745-75-6

Upstream product

• 110-53-2 1-Bromopentane 
• 93-91-4 1-phenylbutan-1,3-dione 
• 98-88-4 benzoyl chloride 
• 78-94-4 methyl vinyl ketone 
• 136801-74-6 2,2-dimethyl-6-(2-oxo-2-phenylethyl)-4H-1,3-dioxin-4-one 
• 4231-62-3 1-benzoyl-1H-benzotriazole 
• 628-17-1 amyl iodide 
• 857249-03-7 6-(1-benzoylhexyl)-2,2-dimethyl-4H-1,3-dioxin-4-one 
• 111-13-7 hexyl-methyl-ketone 

Downstream Products

• 331825-31-1 (5Z,8Z,10E)-12-(tert-Butyl-diphenyl-silanyloxy)-15-diazo-14-oxo-icosa-5,8,10-trienoic acid ethyl ester 

Relevant academic research and scientific papers

Triethylgallium as a nonnucleophilic base to generate enolates from ketones

(Chemical Equation Presented) Triethylgallium deprotonated cyclic and acyclic ketones at 125-175°C without forming carbonyl addition products, and the resulting gallium enolates underwent facile C-benzoylation and an aldol reaction. Unsymmetrical ketones were preferentially enolized at the methylene moiety, which was under kinetic control.

Facile syntheses of 2,2-dimethyl-6-(2-oxoalkyl)-1,3-dioxin-4-ones and the corresponding 6-substituted 4-hydroxy-2-pyrones

A variety of 2,2-dimethyl-6-(2-oxoalkyl)-1,3-dioxin-4-ones 5a-l and the corresponding 6-substituted 4-hydroxy-2-pyrones 3a-l were prepared in high yields under mild reaction conditions by the reaction of 2,2,6-trimethyl-1,3- dioxin-4-one 4 with 1-acylbenz

Total synthesis of the four enantiomerically pure diastereomers of 8-F2t-isoprostane

Syntheses of the four enantiomerically pure diastereomers of 8-F2t-isoprostane (5-8) are described. The key to this approach was to prepare the racemic alcohol 9 in high diastereomeric purity and then resolve 9 by lipase-mediated acetylation to yield the enantiomerically pure alcohols 39 and 32.

2-Acyl-3-substituted cyclopentan-1-ones and process for their preparation

1,3-Dicarbonyl compounds useful as medicines, agricultural chemicals, perfumes, and their intermediates are prepared by reacting a specific α,β-unsaturated carbonyl compound with a specific organic copper lithium compound in the presence of an aprotic inert organic solvent, and then reacting the reaction product with an organic carboxylic acid halide or anhydride. In particular, novel 2-acyl-3-substituted cyclopentan-1-ones and 2-acyl-3-substituted cyclohexan-1-ones having important physiological activities are provided.