57548-40-0Relevant academic research and scientific papers
Kinetic isotope and thermodynamic analysis of the nornicotine-catalyzed aqueous aldol reaction
Rogers, Claude J.,Dickerson, Tobin J.,Janda, Kim D.
, p. 352 - 356 (2006)
A series of kinetic isotope effects and thermodynamic studies were performed to test key predictions of a computationally derived model for a nornicotine-catalyzed aqueous aldol reaction. The relative energies of the two computationally-derived transition
Study on guanidine-based task-specific ionic liquids as catalysts for direct aldol reactions without solvent
Zhu, Anlian,Jiang, Tao,Han, Buxing,Huang, Jun,Zhang, Jicheng,Ma, Xiumin
, p. 736 - 740 (2006)
In this work, the effect of the anions of tetramethylguanidine-based ionic liquids on the catalytic activity in direct aldol reactions was studied. In solvent-free conditions at room temperature, [TMG][Ac] (1,1,3,3- tetramethylguanidinium acetate) was fou
Enantiopure Peptide-Functionalized Metal-Organic Frameworks
Bonnefoy, Jonathan,Legrand, Alexandre,Quadrelli, Elsje Alessandra,Canivet, Jér?me,Farrusseng, David
, p. 9409 - 9416 (2015)
We present herein the first example of metal-organic frameworks postfunctionalized with peptides. Our microwave-assisted postsynthetic modification method yields enantiopure peptides anchored inside MOF cavities. Al-MIL-101-NH2, In-MIL-68-NHsu
ASSISTANT EFFECTS OF CYCLODEXTRINS ON THE ALDOL REACTIONS CATALYZED BY ZINC(II) COMPLEXES OF L-TYROSINE ESTER
Nakagawa, Nasaji,Maruki, Mitsuya,Watanabe, Ken-Ichi
, p. 1025 - 1028 (1985)
Inclusion compounds of α- and β-cyclodextrins(CD) with p-nitrobenzaldehyde were prepared.They underwent the aldol reactions with acetone in the presence of Zn2+ complexes of L-tyrosine ester to afford an enantiomeric excess aldol-type product.The reactions of the β-CD compound were superior to that of the α-CD one both in reactivity and asymmetric induction.
Remarkable increase in basicity associated with supramolecular gelation
Rodriguez-Llansola, Francisco,Escuder, Beatriu,Miravet, Juan F.
, p. 3091 - 3094 (2009)
l-Proline derivatives which are able to form supramolecular gels show an amazing basicity increase in the aggregated (gel) state as compared to solution. As a result they behave as enantioselective catalysts for the aldol reaction in solution but produce
Direct asymmetric aldol reaction catalyzed by nanocrystalline magnesium oxide
Choudary,Chakrapani, Lakkoju,Ramani, Thekkathu,Kumar, K. Vijay,Kantam, M. Lakshmi
, p. 9571 - 9576 (2006)
Nanomaterials with their three-dimensional structure and defined size and shape are considered to be suitable candidates for proper alignment with prochiral substrates for unidirectional introduction of reacting species to induce an asymmetric centre. The
Protonated chiral prolinamide catalyzed enantioselective direct aldol reaction in water
Chimni, Swapandeep Singh,Mahajan, Dinesh,Babu, V. V. Suresh
, p. 5617 - 5619 (2005)
Protonated chiral prolinamide organocatalysts have been shown to catalyze an enantioselective direct aldol process in water to provide the aldol product in high yield and good enantioselectivity. The two diastereomeric catalysts (S,R)-4b and (S,S)-4c show
Enhancing the synthetic utility of aldolase antibody 38C2
Mondal, Kalyani,Ramesh, Namakkal G.,Roy, Ipsita,Gupta, Munishwar N.
, p. 807 - 810 (2006)
Three-phase partitioning (TPP) treated aldolase antibody 38C2 was evaluated for aldol reaction between p-nitrobenzaldehyde and acetone to give 4-(4′-nitrophenyl)-4-hydroxy-2-butanone. While TPP-treated 38C2 transformed 65% of p-nitrobenzaldehyde, the untr
Nornicotine aqueous aldol reactions: Synthetic and theoretical investigations into the origins of catalysis
Dickerson, Tobin J.,Lovell, Timothy,Meijler, Michael M.,Noodleman, Louis,Janda, Kim D.
, p. 6603 - 6609 (2004)
The recent discovery that nornicotine 1, a minor nicotine metabolite, can catalyze the aldol reaction under physiologically relevant conditions has initiated research efforts into the potential chemical roles of nicotine metabolites. Herein, we disclose s
Rapid analysis of solvent effects on enamine formation by fluorescence: How might enzymes facilitate enamine chemistry with primary amines?
Tanaka, Fujie,Thayumanavan, Rajeswari,Mase, Nobuyuki,Barbas III, Carlos F.
, p. 325 - 328 (2004)
In order to determine factors that facilitate the use of primary amines in biological chemistry, solvent effects on enamine formation with glycine were studied. Solvent effects were rapidly analyzed by monitoring the increase in fluorescence resulting fro
