5766-76-7

Basic information

• Product Name: 2-(benzylideneamino)benzoic acid
• Synonyms: 2-(benzylideneamino)benzoic acid;2-(phenylmethylideneamino)benzoic acid
• CAS NO: 5766-76-7
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.24264
• Mol File: 5766-76-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 441°Cat760mmHg
• Flash Point: 220.5°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 1.48E-08mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 2-(benzylideneamino)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzylideneamino)benzoic acid(5766-76-7)
• EPA Substance Registry System: 2-(benzylideneamino)benzoic acid(5766-76-7)

Safety Data

• Hazardous Substances Data: 5766-76-7(Hazardous Substances Data)

Usage

Molecular Structure

Consists of a benzene ring with a carboxylic acid group (-COOH) and an amine group (-NH2) attached to it.

Functional Groups

Contains both a carboxylic acid and an amine functional group.

Physical State

Solid.

Appearance

White crystalline powder.

Solubility

Slightly soluble in water, soluble in organic solvents such as ethanol and methanol.

Melting Point

156-158°C.

Boiling Point

Not readily available as it is a solid at room temperature.

Polarity

Polar due to the presence of the carboxylic acid and amine groups.

Reactivity

Can react with other chemicals through its functional groups, such as esterification and amide formation.

Uses

Used as a building block in organic synthesis, potential therapeutic uses as an enzyme inhibitor and treatment for certain diseases, and potential applications in the development of new materials and pharmaceuticals.

InChI:InChI=1/C14H11NO2/c16-14(17)12-8-4-5-9-13(12)15-10-11-6-2-1-3-7-11/h1-10H,(H,16,17)/b15-10+

Upstream product

• 98-88-4 benzoyl chloride 
• 118-92-3 anthranilic acid 
• 100-52-7 benzaldehyde 

Downstream Products

• 62530-49-8 2-{[(2Z)-3-carboxyprop-2-enoyl]amino}benzoic acid 
• 5694-37-1 o-carboxysuccinanilic acid 
• 41513-78-4 2-phthalimidobenzoic acid 
• 19368-08-2 N-phthalic acid monoacyl anthranilic acid 
• 29274-36-0 4-oxo-2-phenyl-4H-benzo[d][1,3]oxazine-1-carboxylic acid anilide 
• 7152-78-5 N-(α-carboxymethylsulfanyl-benzyl)-anthranilic acid 
• 579-93-1 2-(Benzoylamino)benzoic Acid 
• 68847-22-3 2-phenyl-1-(N,N-phthaloyl-glycyl)-1,2-dihydro-benzo[d][1,3]oxazin-4-one 
• 29274-46-2 4-oxo-2-phenyl-4H-benzo[d][1,3]oxazine-1-carboxylic acid 3-methyl-anilide 
• 29274-39-3 4-oxo-2-phenyl-4H-benzo[d][1,3]oxazine-1-carboxylic acid 2-methyl-anilide 
• 37753-64-3 2-{[(Dimethoxy-phosphoryl)-phenyl-methyl]-amino}-benzoic acid 
• 53639-17-1 N-(cyano-phenyl-methyl)-anthranilic acid 
• 99083-59-7 (N-benzalanthranilic acid)ethyltin trichloride 
• 99083-60-0 (N-benzalanthranilic acid)butyltin trichloride 

Relevant articles and documents

Mechanochemistry in action: Exploitation of internal acid catalysis in Solvent-free synthesis of imines and evaluation of radical scavenging activities of imino derivatives

Mechanochemical protocol has been exploited to accomplish the synthesis of imino derivatives from aromatic amines with acidic functionalities and different aromatic aldehydes in excellent to nearly quantitative yields. Presence of acidic groups in the aromatic amines has been found to have profound influence on the course of the reaction. The prepared imines were screened for in vitro antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Some of the prepared imino derivatives displayed good to moderate antioxidant property when compared with standard natural antioxidant (L-ascorbic acid).

Microwave-assisted synthesis, characterization, and antimicrobial activity of some odorant Schiff bases derived from naturally occurring carbonyl compounds and anthranilic acid

Nine odorant Schiff bases, namely 2-(4-methoxybenzylideneamino) benzoic acid, 2-(benzylideneamino) benzoic acid, 2-(3-phenylallylidene amino) benzoic acid, 2-(3,7-dimethyloct-2,6-enylideneamino) benzoic acid, 2-(3,7-dimethyloct-6-enylideneamino) benzoic a

Phl(OAc)2-mediated one-pot synthesis of benzoxazinones from anthranilic acids and aromatic aldehydes

A novel way to synthesise 2-aryl-4H-benzo[d][1,3]oxazin-4-ones has been developed by the cyclisation of Schiff bases with (diacetoxyiodo)benzene. The salient features of this new protocol which starts from an anthranilic acid and an aromatic aldehyde, are