57772-73-3

Basic information

• Product Name: ethyl 2-benzyl-3-phenylpropanoate
• CAS NO: 57772-73-3
• Molecular Formula: C₁₈H₂₀O₂
• Molecular Weight: 268.3502
• Mol File: 57772-73-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 372°C at 760 mmHg
• Flash Point: 133.5°C
• Density: 1.061g/cm³
• Vapor Pressure: 9.95E-06mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: ethyl 2-benzyl-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-benzyl-3-phenylpropanoate(57772-73-3)
• EPA Substance Registry System: ethyl 2-benzyl-3-phenylpropanoate(57772-73-3)

Safety Data

• Hazardous Substances Data: 57772-73-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 618-68-8 2-benzyl-3-phenylpropanoic acid 
• 42597-26-2 2,2-dibenzyl-acetoacetic acid ethyl ester 
• 141-52-6 sodium ethanolate 
• 597-55-7 dibenzylmalonic acid diethyl ester 
• 100-39-0 benzyl bromide 
• 2678-54-8 ketene diethyl acetal 
• 141-97-9 ethyl acetoacetate 
• 100-44-7 benzyl chloride 
• 141-78-6 ethyl acetate 
• 105-53-3 diethyl malonate 
• 607-81-8 diethyl 2-benzylmalonate 
• 73062-47-2 ethyl 2-benzyl-2-cyano-3-phenylpropionate 
• 103-30-0 (E)-1,2-diphenyl-ethene 

Downstream Products

• 101292-78-8 2-benzyl-3-phenylpropanamide 
• 615268-42-3 (4R)-N-benzyl-N-(tert-butyloxycarbonyl)-2,2-dibenzyl-4-diphenylphosphatoxy-5-methyl-5-nitrohexylamine 
• 615268-26-3 (4R)-N-benzyl-2,2-dibenzyl-4-diphenylphosphatoxy-5-methyl-5-nitrohexylamine 
• 615268-41-2 (4R)-N-benzyl-N-(tert-butyloxycarbonyl)-2,2-dibenzyl-4-hydroxy-5-methyl-5-nitrohexylamine 
• 615268-39-8 N-benzyl-N-(tert-butyloxycarbonyl)-2,2-dibenzyl-4-hydroxy-5-methyl-5-nitro-hexylamine 
• 904325-38-8 N-benzyl-2,2-dibenzyl-5-methyl-5-nitro-4-oxo-hexylamine 
• 615268-37-6 5-[N-benzyl-N-(tert-butyloxycarbonyl)]amino-4,4-dibenzyl-pent-1-ene 

Relevant articles and documents

Rhodium Porphyrin Catalyzed Regioselective Transfer Hydrogenolysis of C-C σ-Bonds in Cyclopropanes with iPrOH

A new rhodium porphyrin catalyzed regioselective transfer hydrogenolysis of both activated and unactivated cyclopropanes employing iPrOH as the hydrogen source was discovered. The reaction mechanism for the C-C σ-bond activation of cyclopropanes was identified through an initial radical substitution with rhodium(II) metalloporphyrin radical to give a rhodium porphyrin alkyl, followed by hydrogenolysis with iPrOH to give the corresponding acyclic alkanes and regenerate rhodium(II) metalloporphyrin radical.

Overturning established chemoselectivities: Selective reduction of arenes over malonates and cyanoacetates by photoactivated organic electron donors

The prevalence of metal-based reducing reagents, including metals, metal complexes, and metal salts, has produced an empirical order of reactivity that governs our approach to chemical synthesis. However, this reactivity may be influenced by stabilization of transition states, intermediates, and products through substrate-metal bonding. This article reports that in the absence of such stabilizing interactions, established chemoselectivities can be overthrown. Thus, photoactivation of the recently developed neutral organic superelectron donor 5 selectively reduces alkyl-substituted benzene rings in the presence of activated esters and nitriles, in direct contrast to metal-based reductions, opening a new perspective on reactivity. The altered outcomes arising from the organic electron donors are attributed to selective interactions between the neutral organic donors and the arene rings of the substrates.

Dipeptides as renin inhibitors

Dipeptides are described which are represented by the formula STR1 wherein the various substituents are defined hereinbelow. These compounds have a strong inhibitory efect on human renin, and are useful as a therapeutically active agent for the treatment of hypertension, especially renin-associated hypertension.