57777-76-1

Upstream product

• 13388-88-0 4-chlorophenyl phosphate 
• 42926-80-7 5'-O-(4-monomethoxytrityl)-2'-deoxythymidine 
• 106-48-9 4-chloro-phenol 
• 772-79-2 4-chlorophenylphosphorodichloridate 

Downstream Products

• 57777-77-2 O^5'-(4-methoxy-trityl)-[3']thymidylic acid 4-chloro-phenyl ester 2-cyano-ethyl ester 
• 87774-77-4 C₄₆H₄₅Cl₂N₄O₁₂P 
• 87774-76-3 C₄₆H₄₅ClFN₄O₁₂P 
• 76742-73-9 C₅₈H₅₅Cl₂N₅O₁₅P₂ 
• 71459-50-2 C₃₇H₃₉ClN₇O₁₃P 
• 76742-74-0 C₃₈H₃₉Cl₂N₅O₁₄P₂ 
• 57777-78-3 thymidine-3'-p-chlorophenyl-β-cyanoethyl-phosphate 

Relevant academic research and scientific papers

A SIMPLIFIED STRATEGY FOR THE SYNTHESIS OF DIDEOXYRIBONUCLEOTIDE BLOCKS

The rapid synthesis of dideoxyribonucleotide blocks in 60-85percent isolated yields has been achieved by combining the phosphorylation and condensation steps in a sequential reaction series which also allows the recovery of unreacted nucleotides.

SYNTHESIS OF DEOXYRIBOOLIGONUCLEOTIDES BY USING AROMATIC PHOSPHORAMIDATES AS THE PROTECTING GROUP FOR THE 3'-PHOSPHO ENDS

p-Chlorophenyl phosphoranilidochloridate was used to phosphorylate the 3'-hydroxyl groups of N,5'-O-protected deoxyribonucleotides.These nucleotides served as the 3'-terminal unit in the syntheses of some protected oligonucleotides which were used in a bl