58022-65-4

Basic information

• Product Name: 2-Methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole
• Synonyms: 2-Methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole;4-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine
• CAS NO: 58022-65-4
• Molecular Formula: C₈H₇N₃O
• Molecular Weight: 161.16068
• Mol File: 58022-65-4.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole(58022-65-4)
• EPA Substance Registry System: 2-Methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole(58022-65-4)

Safety Data

• Hazardous Substances Data: 58022-65-4(Hazardous Substances Data)

Usage

General Description

2-Methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole is a chemical compound with the molecular formula C8H7N3O. It is a heterocyclic compound that contains a five-membered ring consisting of three nitrogen atoms and two oxygen atoms. 2-Methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole is used in organic synthesis and pharmaceutical research due to its potential biological activities. It is also used as a building block in the synthesis of various organic compounds. Additionally, 2-Methyl-5-(pyridin-4-yl)-1,3,4-oxadiazole has been studied for its potential applications in the field of medicinal chemistry, particularly as a scaffold for the development of new drug candidates.

Upstream product

• 54-85-3 isoniazid 
• 14389-12-9 5-(4-pyridyl)tetrazole 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 14389-12-9 4-(1H-tetrazol-5-yl)-pyridine 
• 78-39-7 Triethyl orthoacetate 
• 64-19-7 acetic acid 
• 14777-27-6 methyl acetimidate hydrochloride 
• 1078-38-2 N-acetyl-N'-isonicotinoylhydrazine 

Downstream Products

• 1173072-77-9 1-amino-4-(5-methyl-1,3,4-oxadiazol-2-yl)pyridinium mesitylene sulfonate 
• 1208535-68-5 3-(3-methyl-5-(pyridin-4-yl)-1,2,4-triazol-4-yl)benzoic acid 
• 1208535-67-4 4-(3-methyl-5-(pyridin-4-yl)-1,2,4-triazol-4-yl)benzoic acid 
• 1352638-29-9 5-(3-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-4-yl) isophthalic acid 

Relevant articles and documents

Syntheses, structural diversities and characterization of a series of coordination polymers with two isomeric oxadiazol-pyridine ligands

In this work two positional-isomeric oxadiazol-pyridine ligands 3-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine (L1) and 4-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine (L2) have been designed and synthesized. A series of novel coordination polymers, namely [Cd2(μ2-L1)2(μ2-NCS)4]n (1), {[Cd(L1)(μ2-dca)2(H2O)]·H2O}n (2), {[Cu(μ2-L1)2(NCS)2]·0.5H2O}n (3), {[Ag2(μ2-L1)(μ3-L1)2]·2PF6}n (4), {[Ag3(μ2-L1)4(μ2-CF3SO3)(CF3SO3)]·CF3SO3} (5), {[Cd(L2)2(μ2-NCS)2]}n (6), [Ag(μ2-L2)(μ2-CF3SO3)]n (7) and {[Ag(μ2-L2)]·BF4}n (8) have been isolated. Both 1 and 2 are 2D CdII coordination polymers containing infinite {Cd-NCS-Cd} chains (for 1) or infinite {Cd-dca-Cd} layers (for 2), respectively. 3 is a 2D CuII coordination polymer, in which central metal ions are bridged via a bidentate bridging L1 ligand. While when different AgI salts were introduced into the reaction system, 1D AgI coordination polymers 4 and 5 with diverse coordination modes can be isolated. Furthermore, when the isomeric oxadiazol-pyridine L2 is used to replace L1 in the reaction system, 6-8 can be isolated. 6 is a 2D CdII coordination polymer containing {Cd-NCS-Cd} layers. 7 is a 2D neutral AgI coordination polymer while 8 is a 2D cationic AgI coordination polymer. Variable temperature magnetic susceptibility measurements (2-300 K) reveal anti-ferromagnetic interactions between central copper(ii) ions for 3. Solid-state luminescent properties of 1, 2 and 4-8 have been investigated indicating strong fluorescent emissions. Additionally, luminescent measurements illustrate that complex 8 exhibits highly sensitive luminescence sensing for Cr2O72? ions in aqueous solutions with high quenching efficiency Ksv = 2.08 × 104 L mol?1 and low detection limit (0.19 μM (S/N = 3)). 8 also represents the first report of a coordination polymer based on oxadiazol-pyridine derivatives with a luminescence response to Cr2O72? anion pollutants in aqueous solutions.

Fluoroboric acid-Ag (I) coordination compound constructed based on 4-(5-methyl-1,3,4-oxadiazole)pyridine ligand, and synthesis method thereof

The invention discloses a fluoroboric acid-Ag (I) coordination compound constructed based on a 4-(5-methyl-1,3,4-oxadiazole)pyridine ligand, and a synthesis method thereof. According to the present invention, the fluoroboric acid-Ag (I) coordination compound having a two-dimensional structure and using the 4-(5-methyl-1,3,4-oxadiazole)pyridine ligand is synthesized by using monovalent silver ionsAgBF4 as a main body, can adsorb a variety of dyes, and has application potential.

Trifluoromethanesulfonic acid-Ag (I) coordination compound constructed with 4-(5-methyl-1,3,4-oxadiazole)pyridine, and synthesis method thereof

The invention discloses a trifluoromethanesulfonic acid-Ag (I) coordination compound constructed based on 4-(5-methyl-1,3,4-oxadiazole)pyridine, and a synthesis method thereof. According to the present invention, the trifluoromethanesulfonic acid-Ag (I) coordination compound having a two-dimensional structure and using a 4-(5-methyl-1,3,4-oxadiazole)pyridine ligand is synthesized by using the monovalent silver ions AgCF3SO3 as the main body and using 4-(5-methyl-1,3,4-oxadiazole)pyridine as the ligand; and the trifluoromethanesulfonic acid-Ag (I) coordination compound can adsorb a variety of dyes, and has application potential.