582-84-3

Usage

Uses

Used in Pharmaceutical Industry:
Tramadol is utilized as an analgesic agent for the treatment of moderate to severe pain. It is particularly effective in managing postoperative pain, chronic pain conditions, and neuropathic pain. The dual mechanism of action, involving both opioid receptor binding and monoamine reuptake inhibition, contributes to its efficacy in pain management.
Used in Pain Management:
Tramadol serves as an essential component in pain management protocols, offering an alternative to other opioids with a lower potential for abuse and dependence. Its use is justified by its ability to provide effective pain relief while minimizing the risk of addiction and withdrawal symptoms associated with more potent opioids.
Used in Research and Development:
In the field of pharmaceutical research and development, tramadol is employed as a reference compound for the study of opioid analgesics and their mechanisms of action. It aids in the development of new drugs with improved safety profiles and reduced potential for abuse.
Used in Drug Interaction Studies:
Tramadol is also used in studies investigating drug interactions, as it can interact with various medications, including antidepressants, antipsychotics, and other opioids. Understanding these interactions is crucial for ensuring patient safety and optimizing treatment outcomes.

Upstream product

• 93818-04-3 5-(4-benzyloxy-phenyl)-3-methyl-oxazolidin-2-one 
• 21213-89-8 1-(4-hydroxy-phenyl)-2-methylamino-ethanone 
• 74-89-5 methylamine 

Downstream Products

• 58777-87-0 1-(4-methoxyphenyl)-2-(methylamino)ethan-1-ol 
• 2039-58-9 (+/-)-N,N-Dimethyloctopamine 
• 7339-87-9 4-hydroxyphenylacetaldehyde 
• 101102-83-4 1-(3,5-dibromo-4-hydroxy-phenyl)-2-methylamino-ethanol 
• 77862-54-5 2,2,3,3,3-Pentafluoro-propionic acid 2-[methyl-(2,2,3,3,3-pentafluoro-propionyl)-amino]-1-[4-(2,2,3,3,3-pentafluoro-propionyloxy)-phenyl]-ethyl ester 
• 128441-37-2 (+)-2-methylamino-1-(4-hydroxyphenyl)ethanol (+)-3-bromocamphor-8-sulphonate 
• 128441-37-2 (-)-2-methylamino-1-(4-hydroxyphenyl)ethanol (-)-3-bromocamphorsulphonate 
• 5985-28-4 (+)p-synephrine hydrochloride 
• 86046-45-9 4-(2-Benzo[1,3]dioxol-5-yl-3-methyl-oxazolidin-5-yl)-phenol 
• 532-80-9 (+)-Synephrine 
• 614-35-7 (-)-Synephrine 
• 2973-77-5 3,5-dibromo-4-hydroxybenzaldehyde 
• 118-79-6 2,4,6-tribromophenol 
• 292144-13-9 rac-N-(4-chlorobenzyl)-2-(((2-hydroxy-2-(4-hydroxyphenyl)ethyl)(methyl)amino)methyl)-7-methyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide 

Relevant academic research and scientific papers

Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides

This invention relates to a novel solution phase process for the preparation of amide, carbamate, and sulfonamide combinatorial libraries. These libraries have utility for drug discovery and are used to form wellplate components of novel assay kits.

Pharmaceutical formula

The present invention concerns a pharmacological vehicle or carrier system, which makes possible administration of the active ingredient with a high absorption thereof in the blood circulation of the patient treated therewith, in particular also in the case of oral administration. The pharmacological vehicle system according to the invention comprises ultrafine particles of a reaction product of a reactive derivative of an at least dibasic inorganic acid or an alkane-carboxylic acid having 2 or 3 carboxyl groups and optionally one or two hydroxy groups, wherein one bond of the dibasic inorganic acid or one carboxy group of the alkane-carboxylic acid is bonded to a pharmacological active ingredient containing a hydroxy group, SH group and/or a primary or secondary amino group having a ractive hydrogen atom on this group, and the other bond is bonded to the free hydroxy group of a glycerolipid having at least one free hydroxy group on the glycerol. The invention further concerns these reaction products and a process for the preparation of ultrafine particles of these reaction products.