5840-59-5

Basic information

• Product Name: (2Z)-2-(4-methoxyphenyl)-3-phenylprop-2-enenitrile
• Synonyms: 2-(4-Methoxyphenyl)-3-phenylacrylonitrile
• CAS NO: 5840-59-5
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.2805
• Mol File: 5840-59-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 384.6°C at 760 mmHg
• Flash Point: 161.9°C
• Density: 1.12g/cm³
• Vapor Pressure: 4.03E-06mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: (2Z)-2-(4-methoxyphenyl)-3-phenylprop-2-enenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-2-(4-methoxyphenyl)-3-phenylprop-2-enenitrile(5840-59-5)
• EPA Substance Registry System: (2Z)-2-(4-methoxyphenyl)-3-phenylprop-2-enenitrile(5840-59-5)

Safety Data

• Hazardous Substances Data: 5840-59-5(Hazardous Substances Data)

Usage

General Description

The chemical compound "(2Z)-2-(4-methoxyphenyl)-3-phenylprop-2-enenitrile" is a nitrile compound with a molecular formula of C17H13NO. It contains a nitrile group (-CN) and an alkene group (-C=C-) in its structure. The presence of a 2-methoxyphenyl and a phenyl group in the molecule indicates its aromatic nature. (2Z)-2-(4-methoxyphenyl)-3-phenylprop-2-enenitrile may have potential applications in organic synthesis, pharmaceuticals, and materials science due to the presence of aromatic groups and the nitrile functionality, which can participate in various chemical reactions. Further research may be necessary to fully understand its potential uses and properties.

Upstream product

• 141-52-6 sodium ethanolate 
• 100-52-7 benzaldehyde 
• 104-47-2 p-methoxybenzylnitrile 
• 100-51-6 benzyl alcohol 

Downstream Products

• 5840-58-4 2-(4-methoxyphenyl)-3-phenylpropanenitrile 
• 7497-45-2 2-(4-methoxyphenyl)-3-phenylsuccinonitrile 
• 145962-42-1 2-(4-methoxyphenyl)-1-indanone oxime methyl ether 
• 145962-41-0 2-(4-methoxyphenyl)indanamine 
• 39104-22-8 3-Phenyl-2-<4-methoxy-phenyl>-propionsaeure-chlorid 
• 1769-85-3 (±)-2-(4-methoxyphenyl)-3-phenylpropanoic acid 
• 1086-43-7 2-(4-methoxyphenyl)-2,3-dihydro-1H-inden-1-one 

Relevant articles and documents

α-Alkylation of arylacetonitriles with primary alcohols catalyzed by backbone modified N-heterocyclic carbene iridium(i) complexes

A series of backbone-modified N-heterocyclic carbene (NHC) complexes of iridium(i) (1d-f) have been synthesized and characterized. The electronic properties of the NHC ligands have been assessed by comparison of the IR carbonyl stretching frequencies of thein situprepared [IrCl(CO)2(NHC)] complexes in CH2Cl2. These new complexes (1d-f), together with previously prepared1a-c, were applied as catalysts for the α-alkylation of arylacetonitriles with an equimolar amount of primary alcohols or 2-aminobenzyl alcohol. The catalytic activities of these complexes could be controlled by modifying the N-substituents and backbone of the NHC ligands. The NHC-IrIcomplex1fbearing 4-methoxybenzyl substituents on the N-atoms and 4-methoxyphenyl groups at the 4,5-positions of imidazole exhibited the highest catalytic activity in the α-alkylation of arylacetonitriles with primary alcohols. Various α-alkylated nitriles and aminoquinolines were obtained in high yields through a borrowing hydrogen pathway by using 0.1 mol%1fand a catalytic amount of KOH (5 mol%) under an air atmosphere within significantly short reaction times.

Synthesis of non-symmetrical 3,4-diaryl-substituted pyrroles: Implementation for the preparation of lamellarin R

A straightforward method for synthesising symmetrical and non-symmetrical 3,4-diaryl-substituted pyrroles is proposed, consisting of (i) the condensation reaction between phenylacetonitriles and aldehydes to give acrylonitriles, (ii) the conjugate additio

A Paal-Knorr approach to 3,4-diaryl-substituted pyrroles: Facile synthesis of lamellarins O and Q

A very simple, yet efficient synthetic methodology, to obtain 3,4-diaryl-substituted pyrroles is described. The approach is based on the Knoevenagel condensation between arylacetonitriles and substituted aromatic aldehydes, followed by conjugate addition of cyanide to afford succinonitriles in excellent yields. The products thus obtained were subjected to DIBAL-H reduction, followed by cyclization under acidic conditions to produce the corresponding pyrroles in good overall yields. The utility of this protocol is exemplified by the synthesis of the marine alkaloids lamellarins O and Q.