58556-55-1

Basic information

• Product Name: 4-(2-ACETOXY-ETHYL)PHENOL
• Synonyms: 4-(2-ACETOXY-ETHYL)PHENOL;2-(p-Hydroxyphenyl)ethyl Acetate;4-Hydroxy-benzeneethanol 1-Acetate;4-Hydroxyphenethyl Acetate;Acetic Acid 2-(4-Hydroxyphenyl)ethyl Ester
• CAS NO: 58556-55-1
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.20048
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 58556-55-1.mol
• Article Data: 56

Chemical Properties

• Boiling Point: 300.3 °C at 760 mmHg
• Flash Point: 128 °C
• Appearance: off-white solid
• Density: 1.146 g/cm³
• Vapor Pressure: 0.000634mmHg at 25°C
• Refractive Index: 1.532
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: 4-(2-ACETOXY-ETHYL)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-ACETOXY-ETHYL)PHENOL(58556-55-1)
• EPA Substance Registry System: 4-(2-ACETOXY-ETHYL)PHENOL(58556-55-1)

Safety Data

• Hazardous Substances Data: 58556-55-1(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Tyrosol derivative

InChI:InChI=1/C10H12O3/c1-8(11)13-7-6-9-2-4-10(12)5-3-9/h2-5,12H,6-7H2,1H3

Upstream product

• 501-94-0 p-hydroxyphenethyl alcohol 
• 60759-49-1 N-acetyl-1,3-oxazol-2-one 
• 95-47-6 o-xylene 
• 17207-22-6 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethyl acetate 
• 108-22-5 Isopropenyl acetate 
• 108-05-4 vinyl acetate 
• 155164-63-9 2-acetyl-4,5-dichloropyridazin-3(2H)-one 
• 5471-51-2 4-(4-hydroxyphenyl)-2-oxobutane 
• 406-95-1 2,2,2-trifluoroethyl acetate 
• 75-36-5 acetyl chloride 
• 64-19-7 acetic acid 
• 14140-15-9 4-(2-bromoethyl)phenol 
• 127-09-3 sodium acetate 
• 141-78-6 ethyl acetate 

Downstream Products

• 69039-02-7 2-(3,4-dihydroxyphenyl)ethyl acetate 
• 1309650-13-2 C₂₀H₂₂O₆ 
• 1448451-00-0 2-(1-(but-2-yn-1-yloxy)-4-oxocyclohexa-2,5-dien-1-yl)ethyl acetate 
• 1312922-18-1 2-(2-(1H-indol-3-yl)-4-methoxyphenyl)ethanol 
• 596804-01-2 4-{[1-(tert-butyl)-1,1-dimethylsilyl]oxy}phenethyl acetate 
• 150994-03-9 mesoporphyrin II bis<2-(3-formyl-4-hydroxyphenyl)-ethyl>ester 
• 110005-81-7 2-hydroxy-5-(2-hydroxyethyl)-benzaldehyde 
• 93675-90-2 rengyol diacetate 
• 101489-38-7 trans-1-(2-hydroxyethyl)cyclohexane-1,4-diol 
• 93675-85-5 rengyol 
• 107389-92-4 4-hydroxy-4-(2'-acetoxyethyl)cyclohexanone 

Relevant articles and documents

Chemoenzymatic synthesis and radical scavenging of sulfated hydroxytyrosol, tyrosol, and acetylated derivatives

Potential metabolites of bioactive compounds are important for their biological activities and as authentic standards for metabolic studies. The phenolic compounds contained in olive oil are an important part of the human diet, and therefore their potenti

Optimization of lipase-catalyzed synthesis of acetylated tyrosol by response surface methodology

The ability of a noncommercial immobilized lipase from Staphylococcus xylosus (SXLi) to catalyze the transesterification of tyrosol and ethyl acetate was investigated. Response surface methodology was used to evaluate the effects of the tempera

Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides

Fatty acid monoesters of hydroxytyrosol [2-(3,4-dihydroxyphenyl)ethanol] were synthesized in two steps from tyrosol (4-hydroxyphenylethanol) by successive Candida antarctica lipase B-catalyzed chemoselective acylation on the primary aliphatic hydroxy group over phenolic hydroxy group in tyrosol, and 2-iodoxybenzoic acid (IBX)-mediated hydroxylation adjacent to the remaining free phenolic hydroxy group. Examination of their suppression effects on nitric oxide production stimulated by lipopolysaccharides in RAW264.7 cells showed that hydroxytyrosol butyrate exhibited the highest inhibition (IC50 7.0 μM) among the tested compounds.

Lipase-mediated selective acetylation of primary alcohols in ethyl acetate

An environmental friendly process to selectively acetylate primary alcohols was demonstrated. The esterification process consists of treatment of a primary alcohol in the presence of immobilized C. antarctica lipase (Novozyme-435) in ethyl acetate at room temperature. Primary alcohols were acetylated in the presence of secondary alcohols and phenols.