58787-04-5Relevant articles and documents
Facile Synthesis of Onychines
Arita, Mao,Yokoyama, Soichi,Asahara, Haruyasu,Nishiwaki, Nagatoshi
, p. 2007 - 2013 (2019/04/26)
The FeCl 3 -mediated condensation of an α-phenylenamino ester and an enone proceeds efficiently to afford a 2-phenylnicotinate. The subsequent intramolecular Friedel-Crafts reaction yielded an onychine framework. Modifications at the 2-, 3-, and 8-positions of the onychine framework were easily achieved by altering the enamino esters and enones, which facilitated the discovery of potentially bioactive compounds.
A short-step synthesis of onychine and the related 4-azafluorenones via hetero diels-alder reaction of 5-substituted isotellurazoles
Taneichi, Yusuke,Shimada, Kazuaki,Korenaga, Toshinobu
, p. 440 - 451 (2018/03/27)
Synthesis of onychine and the related 4-azafluorenones was achieved from 5-substituted isotellurazoles through a two-step procedure involving hetero Diels-Alder reaction with methyl phenylpropiolate and the subsequent Friedel-Crafts ring closure of the re
Synthesis of substituted azafluorenones from dihalogeno diaryl ketones by palladium-catalyzed auto-tandem processes
Marquise, Nada,Dorcet, Vincent,Chevallier, Floris,Mongin, Florence
supporting information, p. 8138 - 8141 (2015/01/09)
Substituted azafluorenones were synthesized from different dihalogeno diaryl ketones under palladium catalysis by combining either Suzuki or Heck coupling with direct cyclizing arylation. Conditions were identified to allow both auto-tandem processes to p