588703-29-1

Basic information

• Product Name: Methyl benzofuran-6-carboxylate
• Synonyms: Methyl benzofuran-6-carboxylate;Methyl 1-benzofuran-6-carboxylate
• CAS NO: 588703-29-1
• Molecular Formula: C₁₀H₈O₃
• Molecular Weight: 176.16872
• Mol File: 588703-29-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 257.7±13.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl benzofuran-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl benzofuran-6-carboxylate(588703-29-1)
• EPA Substance Registry System: Methyl benzofuran-6-carboxylate(588703-29-1)

Safety Data

• Hazardous Substances Data: 588703-29-1(Hazardous Substances Data)

Usage

General Description

Methyl benzofuran-6-carboxylate is a chemical compound with the molecular formula C11H10O3. It is an ester derived from benzofuran and carboxylic acid. Methyl benzofuran-6-carboxylate is primarily used in organic synthesis and pharmaceutical research as a versatile building block for the creation of various pharmacologically active compounds. Methyl benzofuran-6-carboxylate has shown potential in the development of anti-cancer and anti-inflammatory drugs, as well as in the production of fragrances and flavorings. Its unique structure and reactivity make it a valuable tool in the development of new molecules with potential therapeutic applications.

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 227752-25-2 trifluoromethanesulfonic acid benzofuran-6-yl ester 
• 478169-68-5 methyl 3-hydroxy-4-[(trimethylsilyl)ethynyl]benzoate 
• 13196-11-7 6-hydroxybenzofuran 
• 6272-26-0 6-hydroxybenzofuran-3-one 
• 299912-77-9 6-(tert-butyl-dimethylsilanyloxy)-[2H]-benzofuran-3-one 
• 77095-51-3 benzofuran-6-carboxylic acid 
• 74-88-4 methyl iodide 
• 58123-77-6 3-hydroxy-4-iodobenzoic acid 
• 619-12-5 4-formyl-3-hydroxybenzoic acid 
• 99-06-9 3-Carboxyphenol 
• 24589-98-8 methyl 4-formyl-3-hydroxybenzoate 
• 1034-49-7 (bromomethyl)triphenyl phosphonium bromide 

Downstream Products

• 1194550-67-8 ((S)-benzyl 2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-methylsulfonyl)phenyl)propanoate 
• 1025967-78-5 (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid 
• 1083168-69-7 (2,3-dihydrobenzofuran-6-yl)methanol 
• 1056942-24-5 1-benzofuran-6-ylmethanol 
• 77095-51-3 benzofuran-6-carboxylic acid 

Relevant articles and documents

GLUE DEGRADERS AND METHODS OF USE THEREOF

Described herein are glue degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment or prevention of conditions, diseases, and disorders mediated by various target proteins.

Preparation method of benzofuran derivative

The invention discloses a preparation method for synthesizing a benzofuran derivative. The specific implementation method is as shown in the specification. The method has novel synthetic route, simpleand convenient operation, high yield, and good safety, and is suitable for industrial production. A novel synthetic method of an intermediate VI is also designed, a Wittig reaction is carried out, and then ring-closing is carried out to obtain a benzofuran ring.

LFA-1 INHIBITOR AND POLYMORPH THEREOF

Methods of preparation and purification of a compound, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA -1 mediated diseases are also disclosed.