5888-97-1

Basic information

• Product Name: 1,3,4-Oxadiazole, 2,2'-(1,4-phenylene)bis[5-phenyl-
• CAS NO: 5888-97-1
• Molecular Formula: C22H14N4O2
• Molecular Weight: 366.379
• Mol File: 5888-97-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3,4-Oxadiazole, 2,2'-(1,4-phenylene)bis[5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Oxadiazole, 2,2'-(1,4-phenylene)bis[5-phenyl-(5888-97-1)
• EPA Substance Registry System: 1,3,4-Oxadiazole, 2,2'-(1,4-phenylene)bis[5-phenyl-(5888-97-1)

Safety Data

• Hazardous Substances Data: 5888-97-1(Hazardous Substances Data)

Usage

Chemical structure

The compound has a 1,3,4-oxadiazole core structure and bisphenyl functionality.

Potential applications

It is used in various fields, including pharmaceuticals, agrochemicals, and materials science.

Building block

It is often used as a building block for the synthesis of organic molecules with desirable properties.

Properties of synthesized molecules

The synthesized molecules can have high thermal stability, optical activity, or biological activity.

Bisphenyl moiety

The bisphenyl moiety in this compound can impart increased rigidity and strength to polymers and other materials.

Versatility

The unique combination of the 1,3,4-oxadiazole core and bisphenyl functionality makes this compound a versatile and valuable chemical building block within the realm of organic synthesis and material science.

Upstream product

• 98-88-4 benzoyl chloride 
• 109495-16-1 5-[4-(5-phenyl-[1,3,4]oxadiazol-2-yl)-phenyl]-1⁽²⁾H-tetrazole 
• 68-36-0 1,4-bis(trichloromethyl)benzene 
• 613-94-5 benzoic acid hydrazide 
• 65-85-0 benzoic acid 
• 136-64-1 terephthalohydrazide 
• 1874-33-5 4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzonitrile 
• 18039-42-4 5-phenyl-2H-1,2,3,4-tetrazole 
• 6068-72-0 4-cyanobenzoyl chlorIde 
• 623-27-8 terephthalaldehyde, 
• 6926-49-4 5,5'-(1,4-phenylene)bis(1H-tetrazole) 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 100-20-9 terephthaloyl chloride 
• 87187-81-3 terephthalaldehyde bis-benzoylhydrazone 

Relevant articles and documents

Synthesis and antibacterial activity of some novel bis-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and bis-4-thiazolidinone derivatives from terephthalic dihydrazide

A novel series of 1,4-bis(6-(substituted phenyl)-[1,2,4]-triazolo[3,4-b]-1,3,4-thiadiazoles (5a-b) and 4-bis(substituted phenyl)-4-thiazolidinone derivatives (7a-c) have been synthesized from terephthalic dihydrazide (1) through multistep reaction sequence. 1,4-Bis(5-aryl-1,3,4-oxadiazole-2yl) benzene derivatives (2a-f) and bis-substituted terephthalohydrazide (6a-e) were also synthesized from terephthalic dihydrazide by cyclization with various aromatic acids and aldehydes. Terephthalic dihydrazide (1) was obtained from poly(ethylene terephthalate) waste from reaction with hydrazine hydrate in good yield (86%). All the synthesized compounds were screened for their antibacterial activities against various bacteria and fungi strains. Several of these compounds showed potential antibacterial activity.

Novel syntheses of symmetrical 2,5-diaryl-1,3,4-oxadiazoles and 1,4-phenylenebis-1,3,4-oxadiazoles

The reactions of trichloromethylarenes with excess hydrazine hydrate in ethanol gives symmetrical 2,5-diaryl-1,3,4-oxadiazoles in 68-96% yields. The reaction of 1,4-bis(trichloromethyl)benzene with acylhydrazines in an ethanol-pyridine mixture gives the corresponding substituted or unsubstituted 1,4-phenylenebis-1,3,4-oxadiazoles in 35-51% yields. The mass spectra of 2,5-diaryl-1,3,4-oxadiazoles and 1,4-phenylenebis-1,3,4-oxadiazoles were studied.