5925-67-7

Basic information

• Product Name: 4-Chlorothiobenzoic acid S-methyl ester
• Synonyms: 4-Chlorothiobenzoic acid S-methyl ester
• CAS NO: 5925-67-7
• Molecular Formula: C₈H₇ClOS
• Molecular Weight: 246.2188
• Mol File: 5925-67-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 311.1°Cat760mmHg
• Flash Point: 141.9°C
• Appearance: /
• Density: 1.373g/cm³
• Vapor Pressure: 0.000576mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 4-Chlorothiobenzoic acid S-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chlorothiobenzoic acid S-methyl ester(5925-67-7)
• EPA Substance Registry System: 4-Chlorothiobenzoic acid S-methyl ester(5925-67-7)

Safety Data

• Hazardous Substances Data: 5925-67-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H10N2O4/c1-8-5-6-11(18-8)12(15)13-9-3-2-4-10(7-9)14(16)17/h2-7H,1H3,(H,13,15)

Upstream product

• 34047-39-7 4-methylsulfanyl-2-butanone 
• 201230-82-2 carbon monoxide 
• 673-41-6 p-chlorobenzenediazonium tetrafluoroborate 
• 74-88-4 methyl iodide 
• 5418-86-0 tris(methylthio)methane 
• 122-01-0 4-chloro-benzoyl chloride 
• 556-64-9 methyl thiocyanate 
• 74-11-3 para-chlorobenzoic acid 
• 75626-81-2 C₂H₃OS⁽¹⁺⁾*F₆Sb^(1-) 
• 108-90-7 chlorobenzene 

Downstream Products

• 5925-80-4 1-chloro-4-((methylsulfonyl)methyl)benzene 
• 171897-88-4 p-chlorophenyl di(methylthio)methyl ketone 
• 152423-67-1 1-(4-Chloro-phenyl)-2,2,2-tris-methylsulfanyl-ethanone 
• 74-11-3 para-chlorobenzoic acid 
• 5925-82-6 (4-chlorobenzyl)(methyl)sulfane 
• 18362-49-7 1,3-bis(4-chlorophenyl)propane-1,3-dione 

Relevant articles and documents

Palladium Catalyzed Direct Carbonylative Thiomethylation of Aryldiazonium Salts and Amines with 4-(Methylthio)-2-Butanone as (Methylthio) Transfer Agent

Herein, an interesting palladium-catalyzed procedure for the direct carbonylative thiomethylation of aromatic amine derivatives with 4-methylthio-2-butanone is developed. Using 4-methylthio-2-butanone as (methylthio) transfer agent, a variety of corresponding thioesters are obtained with moderate to good yields under base-free condition. In addition, good functional group tolerance can be observed.

Synthesis of trimethyl α-keto trithioorthoesters and dimethyl α-keto dithioacetals by reaction of acyl chlorides, anhydrides, thiol esters, and N,N-dimethylamides with [tris(methylthio)methyl]lithium

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Aromatic Substitution. 46. Methyl (Ethyl) Thio(Dithio)carboxylation of Aromatics with S-Methyl (S-Ethyl) Thiocarboxonium and Dithiocarboxonium Fluoroantimonates

S-Methyl(S-ethyl)thio(dithio)carboxinium ions were prepared by reacting methyl(ethyl) fluoride-antimony pentafluoride with carbonyl sulfide (carbon disulfide) and studied with 1H and 13C NMR spectroscopy.The ions were subsequently used in the novel carboxylation reaction of arenes to S-methyl (S-ethyl) thio(dithio)benzoates.The method was also found to be adaptable to the carboxylation of polystyrene to poly(styrenecarboxylic acid) without degradation of the polymer backbone.