5925-82-6

Usage

Uses

Used in Organic Synthesis:
4-CHLOROBENZYL METHYL SULFIDE is used as an intermediate in organic synthesis for the production of various chemical compounds. Its unique structure allows it to serve as a building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 4-CHLOROBENZYL METHYL SULFIDE is used as a precursor in the synthesis of certain pharmaceutical substances. Its presence in the production process contributes to the development of new drugs and medications.
Used in Insect Repellent Research:
4-CHLOROBENZYL METHYL SULFIDE has been studied for its potential use in insect repellents. It has demonstrated efficacy against specific insect species, making it a candidate for further research and development in the field of pest control.
Used in Industrial Processes:
This chemical compound is also found in various industrial processes, where it plays a role in the manufacturing of different products. Its versatility and reactivity contribute to its utility in these applications.
It is crucial to handle 4-CHLOROBENZYL METHYL SULFIDE with care, as it may pose risks if ingested or inhaled, highlighting the importance of proper safety measures during its use and manipulation.

InChI:InChI=1/C15H13FN2O3/c1-20-13-7-5-10(6-8-13)14(17)18-21-15(19)11-3-2-4-12(16)9-11/h2-9H,1H3,(H2,17,18)

Upstream product

• 5925-67-7 methyl chlorobenzenethiocarboxylate 
• 2373-51-5 chloro-methylsulfanyl-methane 
• 108-90-7 chlorobenzene 
• 59662-65-6 methylthiomethyl p-tolyl sulfone 
• 74-93-1 methylthiol 
• 622-95-7 4-chlorobenzyl bromide 
• 122-01-0 4-chloro-benzoyl chloride 
• 373-68-2 tetramethylammonium fluoride 
• 6258-66-8 (4-chlorophenyl)methanethiol 
• 5188-07-8 sodium thiomethoxide 

Downstream Products

• 51392-49-5 α-Brom-4-chlorbenzyl-methylsulfon 
• 5925-80-4 1-chloro-4-((methylsulfonyl)methyl)benzene 
• 29972-67-6 p-Chlorbenzyl-methyl-phenacyl-sulfonium-bromid 
• 24176-68-9 (S)-4-chlorobenzyl methyl sulfoxide 
• 24890-40-2 p-Chlorbenzyl-methyl-phenacyl-sulfonium-ylid 

Relevant academic research and scientific papers

Selective Methylation of Amides, N-Heterocycles, Thiols, and Alcohols with Tetramethylammonium Fluoride

We herein disclose the use of tetramethylammonium fluoride (TMAF) as a direct and selective methylating agent of a variety of amides, indoles, pyrroles, imidazoles, alcohols, and thiols. The method is characterized by operational simplicity, wide scope, and ease of purification. Our computational studies suggest a concerted methylation-deprotonation as the preferred reaction pathway.

BIOTRANSFORMATION OF ORGANIC SULFIDES. PART 6. FORMATION OF CHIRAL para-SUBSTITUTED BENZYL METHYL SULFOXIDES BY HELMINTHOSPORIUM SPECIES NRRL 4671

The fungus Helminthosporium species NRRL 4671 has been used for the biotransformation of a series of para-substituted benzyl sulfides with substituent groups consisting of trifluoromethyl, halo, hydroxy, methoxy, acetoxy, nitro, cyano, amino, acetamido, acyl and carboxylic acid units.In all cases, sulfoxide formation occurred in good yoeld and with predominant (S) chirality at the sulfur position.A minor amount of sulfone product was also obtained from the halo- and methoxy-substituted substrates.

Superelectrophilic methylthiomethylation of aromatics with chloromethyl methyl sulfide/aluminum chloride (MeSCH2Cl:2 AlCl3) reagent

Effective methylthiomethylation of aromatics was achieved by using chloromethyl methyl sulfide/aluminum chloride (MeSCH2Cl:2 AlCl3) as the alkylating agent. Excess aluminum chloride activates the thiocarboxonium ion intermediate by coordinating with sulfur and thus diminishes back donation of 'electron density' into the carbocationic center, rendering it a superelectrophilic methylthiomethylating agent.

NOVEL AND EFFECTIVE METHODS FOR α-THIOALKYLATION OF AROMATIC COMPOUNDS

Convenient and effective methods for the introduction of a methylthiomethyl group and other α-thioalkyl group into aromatic compounds are described.