5934-57-6

Usage

Chemical structure

A complex chemical compound with several functional groups, including a phenyl ring, a morpholine group, a thiomorpholine group, and a pyrrolidine-2,5-dione ring.

Substitution pattern

The phenyl ring is substituted with a morpholine group and a thiomorpholine group.

Linkage

The morpholine group is attached to the phenyl ring via a sulfonyl linkage, and the thiomorpholine group is attached to the pyrrolidine-2,5-dione ring.

Potential applications

Organic synthesis and drug development due to its unique and diverse chemical structure.

Further research

Additional research and analysis are required to fully understand the properties and potential uses of 1-[4-(morpholin-4-ylsulfonyl)phenyl]-3-thiomorpholin-4-ylpyrrolidine-2,5-dione.

Functional groups

Contains a sulfonyl group, which is a sulfur-oxygen linkage, and two heterocyclic amine groups (morpholine and thiomorpholine).

Molecular weight

Approximately 430.56 g/mol (calculated from the molecular formula)

Stability

The stability of the compound is not explicitly mentioned, but the presence of multiple heteroatoms and a complex structure may suggest that it could be sensitive to certain reaction conditions or degradation pathways.

Reactivity

The compound's reactivity profile is not provided, but the presence of various functional groups may indicate potential reactivity with certain reagents or under specific conditions.

Structural complexity

The compound has a relatively high degree of structural complexity due to the presence of multiple heteroatoms, a phenyl ring, and two heterocyclic amine groups.

Synthesis

The synthesis of 1-[4-(morpholin-4-ylsulfonyl)phenyl]-3-thiomorpholin-4-ylpyrrolidine-2,5-dione likely involves multiple steps, including the formation of the sulfonyl linkage and the attachment of the morpholine and thiomorpholine groups to the phenyl and pyrrolidine-2,5-dione rings, respectively.

Analytical techniques

Techniques such as NMR, mass spectrometry, and elemental analysis would be useful for characterizing and confirming the structure of 1-[4-(morpholin-4-ylsulfonyl)phenyl]-3-thiomorpholin-4-ylpyrrolidine-2,5-dione.

Safety considerations

As with any new chemical compound, safety precautions should be taken when handling and studying 1-[4-(morpholin-4-ylsulfonyl)phenyl]-3-thiomorpholin-4-ylpyrrolidine-2,5-dione, including proper storage, handling, and disposal procedures.

Upstream product

• 87-79-6 L-sorbose 
• 100-63-0 phenylhydrazine 
• 50-99-7 D-glucose 
• 59-88-1 phenylhydrazine hydrochloride 
• 127-09-3 sodium acetate 
• 106-49-0 p-toluidine 
• 64-19-7 acetic acid 
• 62-53-3 aniline 
• 156-43-4 4-Ethoxyaniline 
• 55905-50-5 O¹-methyl-D-fructose 
• 4429-04-3 1-amino-1-deoxy-D-fructose 
• 2873-29-2 D-glucal triacetate 
• 7664-41-7 ammonia 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 15476-34-3 L_r-1cat_F-1-(2-phenyl-2H-[1,2,3]triazol-4-yl)-butane-1c_F,2t_F,3r_F,4-tetraol 
• 101996-75-2 3,4,5,6-tetra-O-acetyl-L-xylo-hexosulose 1,2-bis(phenylhydrazone) 
• 75869-76-0 L-lyxo-3,6-anhydro-[2]hexosulose-bis-phenylhydrazone 
• 116525-01-0 3-acetamido-3-deoxy-L-4,5-threo-hexosulose 1,2-bis-phenylhydrazone 
• 116524-99-3 3-acetamido-3-deoxy-L-4,5-threo-hexosulose 1-acetylphenylhydrazone 2-phenylhydrazone 
• 116562-91-5 3,4,5,6-tetra-O-acetyl-L-xylo-hexosulose 1-acetylphenylhydrazone 2-phenylhydrazone 
• 101996-80-9 Acetic acid (1R,2S,3S)-2,3,4-triacetoxy-1-[1,2-bis-(acetyl-phenyl-hydrazono)-ethyl]-butyl ester 
• 112072-04-5 L-xylo-[2]hexosulose-1-(benzyl-phenyl-hydrazone) 
• 526-98-7 2-keto-L-gulonic acid 
• 4429-04-3 1-amino-1-deoxy-D-fructose 
• 35522-78-2 3,6-anhydro-D-ribo-hexulose henylosazone 
• 35522-78-2 (2R,3R,4R)-2-[1,2-Bis-(phenyl-hydrazono)-ethyl]-tetrahydro-furan-3,4-diol 
• 75869-72-6 4,5-O-isopropylidene-β-D-erythro-hexulofuranose bis(phenylhydrazone) 
• 3554-89-0 N-acetyl-2,3-di-O-acetyl-3,6-anhydro-D-ribo-hexulose phenylosazone 

Relevant academic research and scientific papers

Synthesis and structural studies of 1-amino-1-deoxy-α-L-xylo-hexulopyranose: L-Sorbosamine

Ketosamines are an important class of glycoconjugates widely employed in clinical diagnostics and implicated in development of diabetic complications, intestinal infections, or advanced cancer, as well as in food organoleptic and nutritional value. We report on the first preparation and structural characterization of 1-amino-1-deoxy-L-sorbose (L-sorbosamine, L-SorNH2). The monosaccharide was synthesized from L-sorbose following a classic phenylosazone protocol. In aqueous solution, L-SorNH2 assumes an anomeric equilibrium consisting of 89.3% α-pyranose, 3.7% β-pyranose, 3.8% α-furanose, 2.4% β-furanose, and 0.9% acyclic keto tautomer. The α-pyranose anomer in crystalline L-SorNH2 × HCl adopts the 2C5 chair conformation, with bond lengths and valence angles comparing well with related sorbopyranose structures. All hydroxyl oxygen atoms, the ammonium group and chloride ion are involved in an extensive hydrogen bonding network which is formed by infinite chains with fused antidromic R7 6(14), R5 4(10), and R4 3(8) cycles. The Hirshfeld surface analysis suggests a significant contribution of the non-polar intermolecular contacts to the crystal structure, as well.

STUDIES ON 3-EPIMERIC 2-HEXULOSE PHENYLOSAZONES. STRUCTURE AND ANOMERIC CONFIGURATION OF THE 3,6-ANHYDRO-OSAZONE DERIVATIVES OBTAINED FROM D-arabino- AND D-ribo-2-HEXULOSE PHENYLOSAZONE

Dehydration of the 3-epimeric 2-hexulose phenylosazones D-arabino-hexulose phenylosazone or D-ribo-hexulose phenylosazone afforded 3,6-anhydro-D-ribo-hexulose phenylosazone (4) as the preponderant isomer from both.The identity of 4 was obtained by t.l.c., and by acylation followed by comparison of the products.Prolonged acetylation with acetic anhydride-pyridine, or by refluxing with acetic anhydride, afforded the same N-acetyldi-O-acetyl derivative.Refluxing 4 with copper sulfate, or the osotriazole with 20percent methanolic sulfuric acid, afforded the C-nucleoside analog, namely, 4-β-D-erythrofuranosyl-2-phenyl-1,2,3-osotriazole (7).The anomeric configurations of 4 and 7 were ascertained from the n.m.r. spectra of their isopropylidene derivatives.The mechanism of the dehydrative cyclization process and the mass spectra of two compounds were discussed.