59721-28-7 Usage
Description
Camostat is a synthetic serine protease inhibitor that exhibits anti-inflammatory and anti-fibrotic properties. It is primarily used to treat chronic pancreatitis and other pancreatic disorders by inhibiting the activity of trypsin, a serine protease that can cause inflammation and tissue damage in the pancreas. With its potential therapeutic benefits in various medical fields, Camostat is a promising compound for a wide range of applications in medicine.
Uses
Used in Pharmaceutical Industry:
Camostat is used as a therapeutic agent for treating chronic pancreatitis and other pancreatic disorders, as it effectively inhibits the activity of trypsin, reducing inflammation and tissue damage in the pancreas.
Used in Oncology:
Camostat is being investigated for its potential to treat cancer due to its anti-inflammatory properties. It may help modulate oncological signaling pathways and exhibit synergistic anticancer effects when combined with conventional chemotherapeutic drugs, enhancing chemo-sensitivity and efficacy in resistant cases.
Used in Viral Infections Treatment:
Camostat has been studied for its potential to treat viral infections, as it may inhibit the activity of serine proteases involved in viral replication and pathogenesis. This could lead to the development of novel antiviral therapies.
Used in Fibrotic Disease Management:
Camostat's anti-fibrotic properties make it a candidate for the treatment of fibrotic diseases, where it may help reduce tissue scarring and improve organ function.
Used in Drug Delivery Systems:
To enhance the efficacy and bioavailability of Camostat, researchers are developing novel drug delivery systems, such as organic and metallic nanoparticles, to improve its delivery and therapeutic outcomes in various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 59721-28-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,7,2 and 1 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 59721-28:
(7*5)+(6*9)+(5*7)+(4*2)+(3*1)+(2*2)+(1*8)=147
147 % 10 = 7
So 59721-28-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H22N4O5/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22/h3-10H,11-12H2,1-2H3,(H4,21,22,23)
59721-28-7Relevant articles and documents
Acyl guanidine compound as well as preparation method and application thereof
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Paragraph 0030, (2020/10/14)
The invention discloses an acyl guanidine compound with a structure as shown in a formula I (See the specification) and pharmaceutically acceptable salt thereof. The invention also discloses a preparation method of the compound. The invention also discloses a pharmaceutical composition taking the compound or pharmaceutically acceptable salt thereof as an active ingredient, and their application tothe prevention or treatment of diseases (such as hypertension, chronic congestive heart failure, antidiuretic hormone secretion disorder syndrome or hyponatremia caused by chronic heart failure/livercirrhosis/antidiuretic hormone secretion disorder) related to an arginine vasopressin V1a receptor, an arginine vasopressin V1b receptor and an arginine vasopressin V2 receptor.