60562-98-3Relevant articles and documents
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Verheijden,Stoffyn
, p. 253,255 (1957)
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Bio-inspired synthesis of rare and unnatural carbohydrates and cyclitols through strain driven epimerization
Mohanrao, Raja,Asokan, Aromal,Sureshan, Kana M.
supporting information, p. 6707 - 6710 (2014/06/23)
We report a bio-inspired, strain driven epimerization of trans-ketals to cis-ketals through an enolate intermediate. Swern oxidation of a hydroxyl group adjacent to a trans-ketal effects both oxidation and its epimerization to cis-ketal. This novel and general strategy allows inversion of up to three contiguous stereocenters and has been illustrated by the synthesis of several unnatural/rare isomers of carbohydrates/cyclitols from their naturally abundant isomers. This journal is the Partner Organisations 2014.
Synthesis of fusion-isomeric imidazopyridines and their evaluation as inhibitors of syn- and anti-protonating glycosidases
Mohal, Narinder,Vasella, Andrea
, p. 100 - 119 (2007/10/03)
The galacto- and gluco-configured imidazopyridines 4 and 5 were synthesised as potential inhibitors of syn-protonating β-glycosidases. Methyl α-D-lyxopyranoside (9) was transformed into the 3,4-anhydro-β-L- riboside 16, which, upon treatment with Et2