607-92-1Relevant articles and documents
NMR studies of hydrogen bonding inte1ractions with secondary amide and urea groups
Deetz, Martin J.,Fahey, Julianne E.,Smith, Bradley D.
, p. 463 - 467 (2001)
The cis/trans ratios for six model secondary amides were determined by 1H NMR in a range of solvent systems. The trans to cis equilibrium in chloroform is only slightly affected by addition of the hydrogen bond donor, trifluorethanol, but the c
Novel 4-phenoxypyridine derivatives bearing imidazole-4-carboxamide and 1,2,4-triazole-3-carboxamide moieties: Design, synthesis and biological evaluation as potent antitumor agents
Chen, Ye,Ding, Shi,Du, Siyuan,Hou, Yunlei,Li, Chunyan,Li, Zhen,Liu, Fang,Liu, Ju,Shen, Jiwei,Wang, Huan,Wei, Hao,Wu, Shuang
, (2022/01/26)
Two series of novel 4-phenoxypyridine derivatives containing imidazole-4-carboxamide and 4-methyl-5-oxo-4,5-dihydro-1,2,4-triazole-3-carboxamide moieties were synthesized and evaluated for their in vitro inhibitory activities against c-Met kinase and anti
Reversible switching between housane and cyclopentanediyl isomers: An isonitrile-catalysed thermal reverse reaction
Beer, Henrik,Bresien, Jonas,Michalik, Dirk,Schulz, Axel,Villinger, Alexander
supporting information, p. 13986 - 13992 (2020/11/02)
The photo-isomerization of an isolable five-membered singlet biradical based on C, N, and P ([TerNP]2CNDmp, 2a) selectively afforded a closed-shell housane-type isomer (3a) by forming a transannular P-P bond. In the dark, the housane-type species re-isomerized to the biradical, resulting in a fully reversible overall process. In the present study, the influence of tBuNC on the thermal reverse reaction was investigated: The isonitrile acted as a catalyst, thus allowing control over the thermal reaction rate. Moreover, tBuNC also reacted with the biradical to form an adductspecies ([TerNP]2CNDmp·CNtBu, 4a), which can be regarded as the resting state of the system. The reactive species 2a and 3a could be re-generated in situ by irradiation with red light. The results of this study extend our understanding of this new class of molecular switches.