609-86-9

Usage

Safety Profile

Poison by an unspecified route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.

InChI:InChI=1/C7H5I2NO2/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2H,10H2,(H,11,12)/p-1

Upstream product

• 118-92-3 anthranilic acid 
• 89-52-1 o-acetylamino-benzoic acid 
• 37960-65-9 potassium anthranilate 
• 457074-74-7 (2-amino-3,5-diiodo-phenyl)-glyoxylic acid 
• 7722-84-1 dihydrogen peroxide 
• 64-19-7 acetic acid 
• 7647-01-0 hydrogenchloride 
• 7790-99-0 Iodine monochloride 
• 5326-47-6 2-amino-5-iodobenzoic acid 

Downstream Products

• 108757-58-0 4-(2-carboxy-4,6-diiodo-phenylhydrazono)-3-methyl-pentenedioic acid-anhydride 
• 17987-78-9 6,8-diiodo-2-methyl-4H-benzo[d][1,3]oxazin-4-one 
• 100540-61-2 6,8-diiodo-3H-quinazolin-4-one 
• 86166-38-3 2-hexanoylamino-3,5-diiodo-benzoic acid 
• 19094-48-5 3,5-diiodobenzoic acid 
• 88-82-4 2,3,5-triiodobenzoic acid 
• 861526-35-4 2-amino-3,5-diiodo-benzoyl chloride 
• 15396-36-8 2-chloro-3,5-diiodo-benzoic acid 
• 105245-11-2 acide acrylamido-2 diiodo-3,5 benzoique 
• 105245-12-3 acide methacrylamido-2 diiodo-3,5 benzoique 
• 19094-52-1 2-acetylamino-3,5-diiodo-benzoic acid 
• 42860-25-3 3,5-diiodobenzoyl chloride 
• 1397833-83-8 (2-amino-3,5-diiodophenyl)(benzotriazole-1-yl)methanone 

Relevant academic research and scientific papers

KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO

Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof: (I) wherein X, Y, R1, R2, R4, R5 R6, R7, R8 and R11 are as defined herein.

Method for the synthesis of many halo benzoic acid

The invention provides a poly-halogenated benzoic acid synthesizing method. The method comprises the following steps: dissolving substituted benzoic acid, halogen and organic strong acid in a polar solvent for increasing temperature, after oxidation at a temperature of 50-70 DEG C, performing heat preservation at the temperature of 60-80 DEG C for 2-6 h, adding a right amount of water, and cooling to a room temperature, so as to obtain poly-halogenated benzoic acid. According to the invention, synthetic reaction is performed in an alcohols solvent, the halogen simple substance is used as a halogenating reagent, a small amount of organic strong acid is added, used as a catalyst, and used for catalyzing the electrophilic substitution reaction of the halogen to benzene rings, and hydrogen peroxide is dropwise added during the reaction to enable the halogen simple substance in the reaction system to be oxidized into halide ions so as to improve the utilization rate of the halogen and achieve the effect of atom economy.