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Cis,Cis-2,4-Hexadiene, also known as (Z,Z)-2,4-Hexadiene, is an organic compound with the molecular formula C6H10. It is a colorless liquid that is insoluble in water and has a strong, pungent odor. This chemical is a conjugated diene, which means it has two carbon-carbon double bonds separated by a single carbon-carbon single bond. The cis,cis configuration indicates that both double bonds are on the same side of the molecule, resulting in a more compact structure compared to the trans,trans isomer. Cis,Cis-2,4-Hexadiene is used as a building block in the synthesis of various organic compounds, particularly in the production of adipic acid, a key component in the manufacture of nylon. It is also used as a solvent and a chemical intermediate in the pharmaceutical and chemical industries. Due to its reactive nature, it is important to handle CIS,CIS-2,4-HEXADIENE with care, as it can be flammable and may cause irritation to the skin, eyes, and respiratory system.

6108-61-8

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6108-61-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6108-61-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,0 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6108-61:
(6*6)+(5*1)+(4*0)+(3*8)+(2*6)+(1*1)=78
78 % 10 = 8
So 6108-61-8 is a valid CAS Registry Number.

6108-61-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name CIS,CIS-2,4-HEXADIENE

1.2 Other means of identification

Product number -
Other names cis-cis-2,4-hexadiene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6108-61-8 SDS

6108-61-8Relevant academic research and scientific papers

One-step hydroprocessing of fatty acids into renewable aromatic hydrocarbons over Ni/HZSM-5: Insights into the major reaction pathways

Xing, Shiyou,Lv, Pengmei,Wang, Jiayan,Fu, Junying,Fan, Pei,Yang, Lingmei,Yang, Gaixiu,Yuan, Zhenhong,Chen, Yong

, p. 2961 - 2973 (2017/02/05)

For high caloricity and stability in bio-aviation fuels, a certain content of aromatic hydrocarbons (AHCs, 8-25 wt%) is crucial. Fatty acids, obtained from waste or inedible oils, are a renewable and economic feedstock for AHC production. Considerable amounts of AHCs, up to 64.61 wt%, were produced through the one-step hydroprocessing of fatty acids over Ni/HZSM-5 catalysts. Hydrogenation, hydrocracking, and aromatization constituted the principal AHC formation processes. At a lower temperature, fatty acids were first hydrosaturated and then hydrodeoxygenated at metal sites to form long-chain hydrocarbons. Alternatively, the unsaturated fatty acids could be directly deoxygenated at acid sites without first being saturated. The long-chain hydrocarbons were cracked into gases such as ethane, propane, and C6-C8 olefins over the catalysts' Br?nsted acid sites; these underwent Diels-Alder reactions on the catalysts' Lewis acid sites to form AHCs. C6-C8 olefins were determined as critical intermediates for AHC formation. As the Ni content in the catalyst increased, the Br?nsted-acid site density was reduced due to coverage by the metal nanoparticles. Good performance was achieved with a loading of 10 wt% Ni, where the Ni nanoparticles exhibited a polyhedral morphology which exposed more active sites for aromatization.

Applications of PC(sp3)P iridium complexes in transfer dehydrogenation of alkanes

Bzier, David,Brookhart, Maurice

, p. 3411 - 3420 (2015/02/19)

Iridium ethylene complexes based on the PC(sp3)P pincer-type triptycene ligand have been synthesized. Complexes bearing various substituents on the phosphines have been investigated as catalysts in transfer dehydrogenation of alkanes. The complex 8a, which bears isopropyl groups, has demonstrated high stability and activity when used as a catalyst in the disproportionation of 1-hexene at 180 °C and in the transfer dehydrogenation of linear and cyclic alkanes with tert-butylethylene as a hydrogen acceptor at 200°C. A similar complex bearing a CH2NMe2 group, 33, allowed support of the catalyst on γ-alumina for operation in a heterogeneous mode.

SYNTHESIS OF PARA-XYLENE AND TOLUENE

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Page/Page column 8-9, (2012/05/20)

A method of making para-xylene or toluene is carried out by: (a) reacting a C5 or C6 linear monoene (itself, or formed from a C5 or C6 linear alkane) with a hydrogen acceptor in the presence of a hydrogen transfer catalyst to produce a C5 or C6 diene; (b) reacting the C5-C6 diene with ethylene to produce a cyclohexene having 1 or 2 methyl groups substituted thereon; and then (c) either (i) dehydrogenating the cyclohexene in the presence of a hydrogen acceptor with a hydrogen transfer catalyst to produce a compound selected from the group consisting of para-xylene and toluene, or (ii) dehydrogenating the cyclohexene in the absence of a hydrogen acceptor with a dehydrogenation catalyst, to produce para-xylene or toluene.

Synthesis of p-xylene from ethylene

Lyons, Thomas W.,Guironnet, Damien,Findlater, Michael,Brookhart, Maurice

supporting information, p. 15708 - 15711,4 (2012/12/11)

As oil supplies dwindle, there is a growing need to develop new routes to chemical intermediates that utilize alternative feedstocks. We report here a synthesis of para-xylene, one of the highest volume chemicals derived from petroleum, using only ethylene as a feedstock. Ethylene is an attractive alternative feedstock, as it can be derived from renewable biomass resources or harnessed from large domestic shale gas deposits. The synthesis relies on the conversion of hexene (from trimerization of ethylene) to 2,4-hexadiene followed by a Diels-Alder reaction with ethylene to form 3,6-dimethylcyclohexene. This monoene is readily dehydrogenated to para-xylene uncontaminated by the ortho and meta isomers. We report here a selective synthesis of para-xylene, uncontaminated by the ortho or meta isomers, using ethylene as the sole feedstock.

Synthesis of p-xylene from ethylene

Lyons, Thomas W.,Guironnet, Damien,Findlater, Michael,Brookhart, Maurice

supporting information, p. 15708 - 15711 (2013/01/14)

As oil supplies dwindle, there is a growing need to develop new routes to chemical intermediates that utilize alternative feedstocks. We report here a synthesis of para-xylene, one of the highest volume chemicals derived from petroleum, using only ethylene as a feedstock. Ethylene is an attractive alternative feedstock, as it can be derived from renewable biomass resources or harnessed from large domestic shale gas deposits. The synthesis relies on the conversion of hexene (from trimerization of ethylene) to 2,4-hexadiene followed by a Diels-Alder reaction with ethylene to form 3,6-dimethylcyclohexene. This monoene is readily dehydrogenated to para-xylene uncontaminated by the ortho and meta isomers. We report here a selective synthesis of para-xylene, uncontaminated by the ortho or meta isomers, using ethylene as the sole feedstock.

Efficient palladium-catalyzed nucleophilic addition of triorganoindium reagents to carbocyclic derivatives

Baker, Lucas,Minehan, Thomas

, p. 3957 - 3960 (2007/10/03)

Palladium (0)-catalyzed allylic substitution reactions employing triorganoindium reagents have been investigated. In situ generated vinyl- and arylindiums react with substituted and unsubstituted cyclohex-2-enyl esters in the presence of 1-3 mol % Pd2(dba)3 to produce vinyl- or arylcyclohexenes in moderate to excellent yields. The stereoselectivity of this process was also examined, and evidence is presented that the reaction proceeds with inversion of stereochemical configuration.

1-Thia-3,4-diazolidine-2,5-dione Functionality: A Photochemical Synthon for the Azo Group

Squillacote, Michael,Felippis, James De

, p. 3564 - 3571 (2007/10/02)

The 1-thia-3,4-diazolidine-2,5-dione functional group was shown to yield azo compounds upon photolysis.This photoreaction when combined with the known ability of this group to react in a Diels-Alder fashion or as a dinucleophile toward alkylating agents greatly increases the utility of this functionality.The dual reactivity of this group was demonstrated in the synthesis of a number of 3,4-dialkyl-1-thia-3,4-diazolodone-2,5-diones.The photolysis of these compounds produced either thermally stable cyclic azo compounds or the decomposition products of thermally unstable azo compounds.

Cyclobutene photochemistry. Substituent and wavelenght effects on the photochemical ring opening of monocyclic alkylcyclobutenes

Leigh, William J.,Zheng, Kangcheng,Clark, K. Brady

, p. 1988 - 1997 (2007/10/02)

The photochemical ring opening of cis- and trans-3,4-dimethyl-, 1,3,4-trimethyl-, and 1,2,3,4-tetramethylcyclobutene (1,3, and 4, respectively) has been investigated in hydrocarbon solution with 193 nm and 214 nm light sources.Ring opening is non-stereospecific in all cases at both wavelenghts.The ratio of dienes formed by the formally allowed to formally forbidden pathways in the photolysis of these compounds is highest (ca. 2) for the trimethylcyclobutenes, and approximately 1 for both cis and trans isomers of the di- and tetramethylcyclobutenes with 193 nm excitation.The diene distributions from photolysis of all compounds but cis-3 show slight wavelength dependence.Gas- and solution-phase UV absorption spectra are reported for 3 and 4, and indicate that there are at least three singlet excited states accessible in the 185-230 nm region in these molecules.The ?,R(3s) state is the lowest energy state in the gas phase in 3 and 4.The results verify that orbital symmetry factors do not play a role ( or a consistent one, at least) in controlling the stereochemistry of the reaction, but they do not allow a firm assignment of the excited state(s) responsible for ring opening.Direct photolysis of these compounds also results in fragmentation to yield Z-2-butene (from cis-3 and 4) or E-2-butene (from trans-3 and 4) in addition to propyne or 2-butyne.The 2-butenes are formed with greater than 90percent stereospecifity in all cases.The structures of the four 3-methyl-2,4-hexadiene isomers obtained from photolysis of 3 have been assigned on the basis of 1H NMR spectroscopy and the results of thermolysis of the two cyclobutene isomers.

On the Stereochemistry of E'- and E''-Reactions

Vogel, Ernst,Caravatti, Giorgio,Franck, Peter,Aristoff, Paul,Moody, Christopher,et al.

, p. 219 - 222 (2007/10/02)

The decarboxylative E'-dehydration of β,γ-unsaturated δ-hydroxy acids with DMF-dineopentylacetal shows SYN-faciality irrespective of whether the conformation of the hydroxy group relative to the double bond axis is anticlinal or synclinal.

Cyclobutene Photochemistry. Nonstereospecific Photochemical Ring Opening of Simple Cyclobutenes

Clark, K. Brady,Leigh, William J.

, p. 6086 - 6092 (2007/10/02)

The photochemistry of bicyclohept-6-ene, bicyclooct-7-ene, and cis- and trans-3,4-dimetylcyclobutene has been investigated in hydrocarbon solution with monochromatic far-ultraviolet (185 and 193 nm) light sources.All of these simple cyclobutene derivatives undergo ring opening to yield the isomeric 1,3-dienes, and the latter three open nonstereospecifically to yield mixtures of the possible geometric isomers.The isomeric 3,4-dimethylcyclobutenes yield different mixtures of the three 2,4-hexadiene isomers, and in each case the mixtures are weighed in favor of the orbital symmetry forbidden isomer(s).Attempts have been made to analyze the relative isomeric diene yields from ring opening of bicyclooctene and the isomeric 3,4-dimethylcyclobutenes within the context of the purely disrotatory, adiabatic ring-opening mechanism that recent ab initio calculations suggest should be possible.While the results for the former compound are consistant with this mechanism, analysis of the relative yields of the isomeric 2,4-hexadienes from photolysis of the latter two compounds indicates that photochemical ring opening by the formally forbidden, conrotatory pathway may compete to some extent with disrotatory ring opening.

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