6140-64-3

Usage

Uses

Used in Pharmaceutical Industry:
1-Methylcyclohexanecarboxaldehyde is used as a key intermediate in the synthesis of Indazole derivatives, which are known as IDO (Indoleamine 2,3-dioxygenase) and TDO (Tryptophan 2,3-dioxygenase) modulators. These modulators have potential applications in the treatment of various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions, by targeting the IDO and TDO enzymes involved in the kynurenine pathway.
In the preparation of Indazole derivatives, 1-Methylcyclohexanecarboxaldehyde serves as a valuable building block, enabling the development of novel and effective therapeutic agents. Its unique structure and reactivity make it an essential component in the synthesis of these biologically active compounds, contributing to advancements in medicine and healthcare.

Synthesis Reference(s)

Journal of the American Chemical Society, 114, p. 4422, 1992 DOI: 10.1021/ja00037a070

Upstream product

• 64-18-6 formic acid 
• 502-41-0 cycloheptanol 
• 16240-37-2 1,2-epoxy-1-methylcycloheptane 
• 1123-25-7 1-methyl-1-cyclohexanecarboxylic acid 
• 30451-98-0 1-Methoxyspiro<2.5>octan 
• 2890-61-1 1-methyl-1-cyclohexancarboxylic acid chloride 
• 2658-60-8 1,1-bis(hydroxymethyl)cyclohexane 
• 53282-55-6 (trimethylsiloxymethylidene)cyclohexane 
• 333-27-7 methyl trifluoromethanesulfonate 
• 14064-13-2 (1-methylcyclohexyl)methanol 
• 2043-61-0 cyclohexanecarbaldehyde 
• 74-88-4 methyl iodide 
• 111-24-0 1,5-dibromo-pentane 
• 825-04-7 methyl 1-methylcyclohexanecarboxylate 

Downstream Products

• 62257-88-9 N,N-dimethyl-1-(1-methylcyclohexyl)methanamine 
• 590-66-9 1,1-dimethylcyclohexane 
• 103168-39-4 1-Methyl-1-diaminomethyl-N.N'-bis-<1-methyl-cyclohexylmethylen>-cyclohexan 
• 21623-78-9 1-methyl-1-vinylcyclohexane 
• 2955-96-6 Methyl-chloracetoxyacetat 
• 153791-49-2 Methyl <(1-methyl-1-cyclohexanecarbonyl)acetoxy>acetate 
• 161139-35-1 methyl N-(4-methoxybenzyl)-N-<3-(1-methylcyclohexyl)-3-oxopropanoyl>glycinate 
• 1123-25-7 1-methyl-1-cyclohexanecarboxylic acid 
• 92319-11-4 (+/-)-Cyclohexyl-<1-methyl-cyclohexyl>-methanol 
• 869997-15-9 5-(2-adamantan-1-yl-ethyl)-2-(1-methyl-cyclohexyl)-1H-imidazole-4-carboxylic acid ethyl ester 
• 951789-75-6 C₁₇H₂₄N₂O 
• 923591-39-3 (2R)-{[(1R)-2-hydroxy-1-phenylethyl]amino}(1-methylcyclohexyl)acetonitrile 
• 951789-86-9 (S)-2-(tert-butoxycarbonylamino)-2-(1-methylcyclohexyl)acetic acid 
• 951789-89-2 C₁₇H₂₅NO₃ 

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