6163-66-2Relevant academic research and scientific papers
PROCESS AND SYSTEM TO MAKE SUBSTITUTED LACTONES
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Paragraph 0052; 0054, (2021/02/05)
A process for oxidizing iso-butane with oxygen to produce t-butyl hydroperoxide and t-butyl alcohol; dehydrating at least a portion of the t-butyl alcohol to produce di-tert-butyl ether and isobutylene; epoxidizing at least a portion of the isobutylene with the t-butyl hydroperoxide to produce isobutylene oxide and t-butyl alcohol; and carbonylating at least a portion of the isobutylene oxide with carbon monoxide to produce pivalolactone.
Synthesis of Benzyl Alkyl Ethers by Intermolecular Dehydration of Benzyl Alcohol with Aliphatic Alcohols under the Effect of Copper Containing Catalysts
Bayguzina,Gimaletdinova,Khusnutdinov
, p. 1148 - 1155 (2018/10/24)
Synthesis of benzyl alkyl ethers was performed in high yields by intermolecular dehydration of benzyl and primary, secondary, tertiary alcohols under the effect of copper containing catalysts. The formation of benzyl alkyl ethers occurs with participation of benzyl cation.
Catalytic etherification of alcohols in Shilov system: C[sbnd]O versus C[sbnd]H bond activation
Khazipov, Oleg V.,Nykytenko, Denys V.,Krasnyakova, Tatyana V.,Vdovichenko, Alexander N.,Fuentes Frias, Dario A.,Mitchenko, Serge A.
, p. 490 - 498 (2016/12/16)
A novel catalytic reaction of alcohol etherification in the system ROH ? PtCl42? ‐ PtCl62? was found. Methanol easily transforms into dimethyl ether in the presence of catalytic amounts of PtII chloro complexes at 70?°C. Under the same conditions reaction of ethanol affords diethyl ether (catalytic) and π-ethylene PtII complex (stoichiometric). The reactions are accompanied by multiple H/D exchange, which is indicative of intermediacy of corresponding alkyl platinum derivatives. The plausible reaction mechanism involves oxidative addition of alcohol forming intermediate alkyl platinum(IV) derivative followed by decomposition of it via reductive elimination step under the action of alcohol giving the ether and regenerating catalyst. In the case of ethyl alcohol reaction, β-hydrogen abstraction from the intermediate Pt-ethyl species yields π-ethylene platinum(II) complex. Although it seems that the reaction does not involve the initial breaking of C[sbnd]H bonds of an alcohol, this system can be regarded as a model for studying of some peculiarities of Shilov chemistry, in particular, of isotope scrambling mechanisms in Shilov alkane activation. In contrast to reactions of dimethyl and diethyl ethers formation, tert-butyl ethers formation in CD3OH/t-BuOH medium is catalyzed by PtIV chloro complexes also and is not accompanied by isotope scrambling. These observations argue against intermediacy of alkyl platinum derivatives suggesting that acid-catalyzed mechanism operates in tert-butyl alcohol etherification.
The feeding at the same time containing butene dimerization and hydrated method (by machine translation)
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Paragraph 0071-0077, (2017/03/22)
The present invention provides a mixed butene by acid catalysts containing hydrocarbon feed of manufacturing and method of the oligomer at the same time. Furthermore, embodiments of the present invention also provides the preparation of the mixed olefin containing the alcohol and the oligomer process for the preparation of the fuel composition, in certain embodiments, the catalyst can include two-phase catalyst system, the catalyst system includes a water-soluble acid catalyst and solid acid catalyst. (by machine translation)
Lactam inhibitors of factor Xa and method
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, (2008/06/13)
Lactam inhibitors are provided which have the structure including pharmaceutically acceptable salts thereof and all stereoisomers thereof, and prodrug esters thereof, wherein n is 1 to 5; and and R1, R2, R3, R4, R5 , R6, R7, R8, R9, R10, R10a, 1011 and R12 are as defined herein. These compounds are inhibitors of Factor Xa and thus are useful as anticoagulants. A method for treating cardiovascular diseases associated with thromboses is also provided.
Compounds having effects on serotonin-related systems
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, (2008/06/13)
A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1A receptor. The compounds are particularly useful for alleviating the sym
The Stoichiometry in the Determination of Water Using Karl Fischer Reagent
Fischer, Wolfgang,Krenn, Karl-Dieter
, p. 569 - 577 (2007/10/03)
The stoichiometry of the Karl Fischer reaction is not unambiguous. The titer of a Karl Fischer solution rises with the amount of water, because sulphur trioxide which is formed as an intermediate consumes water too. An 1:1-stoichiometry (H2O:I2) can be simulated by alcohols, because these solvents also react with iodine and sulphur dioxide leading to additional consumption of iodine during the titration. This interpretation of the results of Karl Fischer titrations is supported by the isolation or identification of pertinent reaction products.
A New Synthesis of Hindered Unsymmetrical t-Alkyl Ethers
Masada, Hiromitsu,Gotoh, Hidenori,Ohkubo, Makoto
, p. 1739 - 1742 (2007/10/02)
The unusual Williamson reactions of t-butyl and t-pentyl halides with lithium t-alkoxides or with t-alkyl alcohols and amines were carried out at 20-50 deg C.Some of the nucleophilic substitution products were new unsymmetrical ethers: t-butyl t-pentyl ether, t-butyl 1,1-dimethyl-2-propenyl ether, t-butyl 1,1-dimethyl-2-propynyl ether, 1,1-dimethyl-2-propynyl t-pentyl ether, and t-butyl 1-ethyl-1-methyl-2-propynyl ether.
