62137-64-8

Basic information

• Product Name: trans-(2S,3R)-2-(4-chlorophenyl)-3-phenyloxirane
• Synonyms: trans-(2S,3R)-2-(4-chlorophenyl)-3-phenyloxirane
• CAS NO: 62137-64-8
• Molecular Weight: 230.694
• Mol File: 62137-64-8.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: trans-(2S,3R)-2-(4-chlorophenyl)-3-phenyloxirane(CAS DataBase Reference)
• NIST Chemistry Reference: trans-(2S,3R)-2-(4-chlorophenyl)-3-phenyloxirane(62137-64-8)
• EPA Substance Registry System: trans-(2S,3R)-2-(4-chlorophenyl)-3-phenyloxirane(62137-64-8)

Safety Data

• Hazardous Substances Data: 62137-64-8(Hazardous Substances Data)

Upstream product

• 1657-49-4 1-chloro-4-[(Z)-2-phenylethenyl]benzene 
• 100-39-0 benzyl bromide 
• 873-76-7 para-Chlorobenzyl alcohol 
• 104-88-1 4-chlorobenzaldehyde 
• 100-52-7 benzaldehyde 
• 27992-27-4 sodium 2-benzylidene-1-tosylhydrazin-1-ide 
• 908094-04-2 phenyldiazomethane 
• 174291-23-7 (-)-(1R,2R)-endo-3-(benzylthio)-1,7,7-trimethylbicyclo<2.2.1>heptan-2-ol 
• 174291-25-9 (+)-(1R,2S)-endo-3-(benzylthio)-1,7,7-trimethylbicyclo<2.2.1>heptan-2-ol 
• 174291-24-8 (1R,2R,3S,4S)-1,7,7-Trimethyl-3-methylsulfanyl-bicyclo[2.2.1]heptan-2-ol 
• 174291-26-0 (1R,2S,3S,4S)-1,7,7-Trimethyl-3-methylsulfanyl-bicyclo[2.2.1]heptan-2-ol 
• 158809-09-7 (-)-(1R,2S)-2-methoxy-exo-3-(benzylthio)-1,7,7-trimethylbicyclo<2.2.1>heptane 
• 174150-18-6 (-)-(1R,2S)-2-methoxy-exo-3-(methylthio)-1,7,7-trimethylbicyclo<2.2.1>heptane 
• 114552-47-5 (+)-exo-3-(Methylthio)-1,7,7-trimethylbicyclo<2.2.1>heptan-2-ol 

Downstream Products

• 623-03-0 4-Cyanochlorobenzene 
• 104-88-1 4-chlorobenzaldehyde 
• 100-52-7 benzaldehyde 
• 100-47-0 benzonitrile 
• 134-85-0 4-chlorobenzophenone 
• 28523-15-1 2-(4-chlorophenyl)-2-phenylacetaldehyde 
• 6332-83-8 2-(4-chlorophenyl)-1-phenylethanone 
• 1889-71-0 4'-chloro-2-phenylacetophenone 

Relevant articles and documents

Method used for direct synthesis of epoxy compounds from alcohol

The invention discloses a method used for direct synthesis of an epoxy compounds from an alcohol. According to the method, an alcohol is taken as a raw material, Swern oxidation is adopted to synthesize an aldehyde, a bromo-hydrocarbon and an alkali are added into the aldehyde directly to construct epoxy functional groups, and generate the epoxy compound. According to the method, one-pot method is adopted to realize direct epoxidation of the alcohol, the synthesis route is simple, the preparation process is easy to control, no catalyst is needed in the process, substrate suitable range is wide, reagents are cheap and easily available, preparation conditions are mild, reaction yield is high, and the method is suitable for synthesis of epoxy compounds.

A novel and highly efficient asymmetric synthesis of epoxides via chiral telluronium ylides

The one-pot reaction of telluronium salt 8, aldehyde, and potassium tert-butoxide proceeded smoothly via chiral benzyl telluronium ylide, producing trans-(2S,3S)-diaryl epoxides with good yields as well as excellent diastereoselectivities and enantioselectivities (up to 99% ee). Georg Thieme Verlag Stuttgart.

Design of sulfides with a locked conformation as promoters of catalytic and asymmetric sulfonium ylide epoxidation

A new generation of 2,5-dimethylthiolanes with a locked conformation was developed to promote the asymmetric addition of chiral sulfonium ylides to aldehydes. The novel chiral sulfur derivative 4 succeeded the synthesis of trans-stilbene oxide derivatives with enantiomeric ratios ranging from 95:5 to 98:2. This user-friendly organocatalytic process proved to be efficient with 20-10% of sulfide 4 in 1 or 2 days of reaction. An insight into the ylide intermediate conformation is given on the basis of a computational ab initio study.