622-82-2

Usage

Physical State

Liquid

Color

Colorless to pale yellow

Odor

Faint

Primary Use

Research and laboratory settings (chemical intermediate)

Secondary Use

Synthesis of other organic compounds

Hazardous Nature

Toxic

Potential Health Risks

Skin and eye irritation, harmful effects from long-term exposure

Safety Precautions

Follow proper safety protocols, use appropriate protective equipment to minimize risk of exposure.

Upstream product

• 935-07-9 acetaldehyde phenylhydrazone 
• 114-83-0 1-acetyl-2-phenylhydrazine 
• 935-08-0 2-ethyl-1-phenyldiazene 
• 129502-47-2 C₂₆H₂₆N₂P⁽¹⁺⁾*I^(1-) 
• 64-17-5 ethanol 
• 7732-18-5 water 
• 74-96-4 ethyl bromide 
• 100-63-0 phenylhydrazine 
• 557-20-0 diethylzinc 
• 64-67-5 diethyl sulfate 
• 75-03-6 ethyl iodide 
• 3614-49-1 1-ethyl-5-methyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one 

Downstream Products

• 101586-87-2 2,5-diethyl-3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid ethyl ester 
• 99981-60-9 propionic acid-(N-ethyl-N'-phenyl-hydrazide) 
• 104440-09-7 2-ethyl-5-methyl-1-phenyl-1,2-dihydro-pyrazol-3-one 
• 39837-50-8 N,N-diethyl-N'-phenyl-hydrazine 
• 21076-24-4 2-Ethyl-1-phenyl-thiosemicarbazid 
• 53656-69-2 1-Ethyl-2-phenyl-1-(2,2,2-trifluorethylcarbimidoyl)-hydrazin 
• 53656-68-1 1-Ethyl-2-phenyl-1-phenylcarbimidoyl-hydrazin 
• 21076-99-3 4-Methyl-2-ethyl-1-phenyl-thiosemicarbazid 
• 53856-26-1 1-Ethyl-2-phenyl-1-(2,2,2-trichlorethylcarbimidoyl)-hydrazin 
• 101938-93-6 2,5-diethyl-3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid 
• 100720-02-3 2,5-diethyl-3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid amide 
• 100970-71-6 2,5-diethyl-3-oxo-1-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid hydrazide 
• 107417-10-7 2,5-diethyl-1-phenyl-1,2-dihydro-pyrazol-3-one 
• 100051-04-5 N,N-diethyl-N'-methyl-N'-phenyl-hydrazine 

Relevant academic research and scientific papers

Aryl Pyrazoles from Photocatalytic Cycloadditions of Arenediazonium

A photocatalytic synthesis of 1,5-diaryl pyrazoles from arenediazoniums and arylcyclopropanols is reported. The reaction proceeded under mild conditions (rt, 20 min) with catalytic [Ru(bpy)3]2+ under blue-light irradiation and exhibited compatibility with several functional groups (e.g., I, SF5, SO2NH2, N3, CN) and perfect levels of regiocontrol. Mechanistic studies (luminescence spectroscopy, CV, DFT, radical trapping, quantum yield determination) documented an initial oxidative quenching of the excited photocatalyst and the operation of a radical-chain mechanism.

Regioselective Synthesis of 1-Alkyl-1-phenylhydrazines, 2-Alkyl-1-phenylhydrazines, and 1,2-Dialkyl-1-phenylhydrazines

1,2- and 1,1-disubstituted and 1,1,2-trisubstituted hydrazines are obtained by reaction of (2-phenylhydrazino)triphenylphosphonium bromide with butyllithium, followed by addition of alkyl halides and alkaline hydrolysis.