6242-98-4

Basic information

• Product Name: 4-BROMO-4'-NITROBIPHENYL
• Synonyms: 4-BROMO-4'-NITROBIPHENYL;4-BroMo-4'-nitro-1,1'-biphenyl
• CAS NO: 6242-98-4
• Molecular Formula: C₁₂H₈BrNO₂
• Molecular Weight: 278.1
• Mol File: 6242-98-4.mol
• Article Data: 15

Chemical Properties

• Melting Point: 173 °C
• Boiling Point: 386.9±17.0 °C(Predicted)
• Appearance: /
• Density: 1.521±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-BROMO-4'-NITROBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-4'-NITROBIPHENYL(6242-98-4)
• EPA Substance Registry System: 4-BROMO-4'-NITROBIPHENYL(6242-98-4)

Safety Data

• Hazardous Substances Data: 6242-98-4(Hazardous Substances Data)

Usage

General Description

4-Bromo-4'-nitrobiphenyl, also known as 4-Bromo-4'-nitrodiphenyl, is a chemical compound that consists of a biphenyl core with a bromine atom at the 4-position and a nitro group at the 4'-position. It is a yellow crystalline solid with a molecular formula C12H8BrNO2. 4-BROMO-4'-NITROBIPHENYL is primarily used as a building block in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It is also used as an intermediate in the production of dyes and pigments. 4-Bromo-4'-nitrobiphenyl is classified as a hazardous substance and should be handled with care due to its potential health and environmental effects.

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Relevant articles and documents

Biaryl Coupling of Aryldiazonium Salts and Arylboronic Acids Catalysed by Gold

A gold-catalysed coupling of aryldiazonium salts with arylboronic acids is described. The reactions proceed in satisfactory yields under irradiation with blue LEDs in the presence of KF and a catalytic amount of ascorbic acid. Notably, 4-nitrobenzendiazonium tetrafluoroborate is sufficiently reactive to undergo the coupling with a variety of arylboronic acids in the absence of aryl radical initiators. The coupling is applicable for electron-donating and electron-withdrawing groups present at the para, ortho, and meta positions of both substrates.

Copper catalysed Gomberg-Bachmann-Hey reactions of arenediazonium tetrafluoroborates and heteroarenediazonium o-benzenedisulfonimides. Synthetic and mechanistic aspects

Gomberg-Bachmann-Hey reactions were carried out in the presence of copper as a catalyst and gave rise to biaryls or heterobiaryls in good yields and in mild reaction conditions. A computational study of some key points of the reaction was performed. The results are coherent with the experimental data and confirm some aspects of the mechanism. The reaction free energies for the reduction in benzene by CuI of a set of 40 (hetero)arenediazonium tetrafluoroborates were calculated. Both the experiments and the calculations showed that in the coupling with substituted solvents (toluene, bromobenzene, nitrobenzene and anisole) the binding to the ortho position was always favoured.

Synthesis, characterization and catalytic performance of palladium supported on pyridine-based covalent organic polymer for Suzuki-Miyaura reaction

A bipyridine-based covalent organic polymer (COP) was successfully synthesized by condensation of trimesoyl chloride (TMC) and 2,2′-bipyridine-5,5′-diamine (Bpy) under ambient conditions. This material was modified by coordination of PdCl2 to COP framework, affording a hybrid material, Pd@TMC-Bpy COP, which was applied as a highly efficient heterogeneous catalyst for Suzuki-Miyaura reaction under ligand-free conditions in ethyl lactate. The catalyst could be reused for five times without obvious loss of its activity.