625-25-2

Usage

Uses

Used in Flavor and Fragrance Industry:
2-Methyl-2-heptanol is used as a flavoring agent for its mild, fruity odor, enhancing the aroma of various food products and beverages.
Used in Plasticizer Production:
2-Methyl-2-heptanol is used as a component in the manufacturing of plasticizers, which are additives that increase the flexibility and workability of plastics.
Used in Perfume and Cosmetics Industry:
2-Methyl-2-heptanol is used as a fragrance ingredient in perfumes and cosmetics, contributing to their pleasant scent.
Used in Pharmaceutical and Agrochemical Synthesis:
2-Methyl-2-heptanol is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, playing a crucial role in the production of various medicinal and agricultural products.
Used in Biofuel Research:
2-Methyl-2-heptanol is studied for its potential use as a biofuel due to its high energy density, offering an alternative to traditional fossil fuels.

InChI:InChI=1/C8H18O/c1-4-5-6-7-8(2,3)9/h9H,4-7H2,1-3H3

Upstream product

• 123-66-0 Ethyl hexanoate 
• 676-58-4 methylmagnesium chloride 
• 111-24-0 1,5-dibromo-pentane 
• 67-64-1 acetone 
• 693-25-4 n-pentylmagnesium bromide 
• 4325-49-9 2-chloro-2-methylheptene 
• 90370-79-9 6-hydroxy-6-methyl-hept-4-en-3-one 
• 111-71-7 heptanal 
• 110-43-0 n-pentyl methyl ketone 
• 917-54-4 methyllithium 
• 2747-38-8 methyltrichlorotitanium 
• 18006-13-8 methyltriisopropoxytitanium(IV) 
• 121826-88-8 C₉H₁₈B^(1-)*Li⁽¹⁺⁾ 
• 121826-81-1 C₁₂H₂₄B^(1-)*Li⁽¹⁺⁾ 

Downstream Products

• 592-27-8 2-methylheptane 
• 627-97-4 2-methyl-2-heptene 
• 15870-10-7 2-methylhept-1-ene 
• 4325-49-9 2-chloro-2-methylheptene 
• 16252-11-2 (2-methylheptan-2-yl)benzene 
• 14352-59-1 3,3-Dimethyl-octansaeure 
• 13393-69-6 (1,1-Dimethyl-hexyl)-hydroperoxid 
• 14250-73-8 2,2-dimethylheptanoic acid 
• 30784-29-3 4-tert-octylphenol 
• 569332-14-5 2-methyl-2-(4-hydroxy-3,5-dimethoxyphenyl)heptane 
• 78945-29-6 2-methyl-2-(3,5-dihydroxyphenyl)heptane 
• 78945-34-3 2-(3,5-dimethoxyphenyl)-2-methylheptane 
• 860532-09-8 4-(2-methylheptan-2-yl)aniline 
• 859977-47-2 2-methyl-2-(4-nitro-phenyl)-heptane 

Relevant academic research and scientific papers

NEW METHODS FOR HYDRODEALKENYLATION

The present disclosure pertains to new methods of performing a hydrodealkenylation of monounsaturated alcohols, thiols, and derivatives thereof, such as terpenes and derivatives, comprising ozonolysis and quenching using a sulfinic acid or sulfinic acid salt.

FRAGRANCE MATERIAL

Fragrance compounds having a unique chemical structure are provided, including 2-methoxy-2-methylheptane and derivatives thereof. The fragrance compounds can have fruity, radish, and/or herbaceous odor notes with a strong top note. The fragrance compounds can be used alone or incorporated into a fragrance composition and/or consumer product to modify or enhance the odor of the fragrance composition and/or consumer product.

Silanol-based surfactants: Synthetic access and properties of an innovative class of environmentally benign detergents

Herein, environmentally friendly surfactants based on new silanols as substitutes for the isoelectronic phosphonates were explored. Surface tensions of aqueous solutions are significantly reduced, particularly with those silanols that feature a high ratio of organic moiety to silanol. Besides their use as surfactants, their potential as coating agents for hydrophilic oxide surfaces was investigated for the example of glass substrates. In the solid-state sheet structures with silanol, double layers are present, in which the sheet spacing varies with the alkyl-chain length. Soap from sand? A synthetic entry to surfactants based on stable silanols, which provide beneficial properties comparable to established detergents without sharing their eutrophicating potential, was established (see figure).

One-pot system for reduction of epoxides using NaBH4, PdCl 2 catalyst, and moist alumina

Reduction of epoxides with sodium borohydride, a catalytic amount of palladium(II) chloride, and chromatographic neutral alumina preloaded with a small amount of water (moist alumina) in hexane gave alcohols in good to excellent yields and good selectivity of the desired products under mild conditions. The reaction system was operationally simple and environmentally friendly. The alumina can be recovered simply and reused a number of times without any treatment and with good activity.

Structure-activity relationships for 1′,1′-dimethylalkyl-Δ8-tetrahydrocannabinols

A series of 1′,1′-dimethylalkyl-Δ8-tetrahydrocannabinol analogues with C-3 side chains of 2-12 carbon atoms has been synthesized and their in vitro and in vivo pharmacology has been evaluated. The lowest member of the series, 1′,1′-dimethylethyl-Δ8-THC (8, n=0) has good affinity for the CB1 receptor, but is inactive in vivo. The dimethylpropyl (8, n=1) through dimethyldecyl (8, n=8) all have high affinity for the CB1 receptor and are full agonists in vivo. 1′,1′-Dimethylundecyl-Δ8-THC (8, n=9) has significant affinity for the receptor (Ki=25.8±5.8 nM), but has reduced potency in vivo. The dodecyl analogue (8, n=10) has little affinity for the CB1 receptor and is inactive in vivo. A quantitative structure-activity relationship study of the side chain region of these compounds is consistent with the concept that for optimum affinity and potency the side chain must be of a length which will permit its terminus to loop back in proximity to the phenolic ring of the cannabinoid.

Reactions of Saturated and Unsaturated Tertiary Alkyl Halides and Saturated Secondary Alkyl Iodides with Lithium Aluminum Deuteride. Convincing Evidence for a Single-Electron-Transfer Pathway

Reactions of saturated secondary and tertiary alkyl halides with LiAlH4 (LAH) and LiAlD4 (LAD) have been carried out, and convincing evidence for a single-electron-transfer (SET) pathway has been obtained. Reactions involving saturated alkyl halides with LAD provide a model system in which a halogen-atom radical chain process is not possible, and therefore, the observation of large quantities (in some cases >90 percent) of protium in the reduction product provides strong evidence for a radical intermediate and a SET pathway. Specifically, the reaction of 2-iodooctane (10) with LAD produced octane with a deuterium content as low as 21 percent. Also, the reaction of the tertiary halide 2-iodo-2-methylheptane (15) with LAD produced 2-methylheptane (16) with a deuterium content as low as 8 percent. The effect of stoichiometry, halogen type, and reaction vessel surface on these reactions was studied. Reaction of the unsaturated tertiary halide 6-iodo-6-methyl-1-heptene (25) with LAD was also studied and was found to proceed predominantly by a SET process involving a halogen-atom radical chain process. The possibility of a carbocation intermediate in all of these reactions is discussed.

Studies on regioselective addition of alkyl(phosphine)copper complexes to epoxides

An alkyl(phosphine)copper complex performed alkylative ring opening of a monosubstituted epoxide, but not that of a 1,2-disubstituted or trisubstituted epoxide, and, by the reaction with this complex, a diepoxy compound comprising terminal and internal epoxy functionalities in a single molecule formed a product based on preferential attack to the terminal one.

Dimethyldioxirane reactions: Rate acceleration due to intramolecular H-bonding

Absolute rate studies were carried out on a series of C - H insertion reactions of dimethyldioxirane (1a). The substrates were chosen so that the distance between a single tertiary C - H bond and an OH group could be varied. The measured rate constants indicate that a rate acceleration occurs when the distance between the reacting C - H bond and the OH group permits intramolecular H-bonding stabilization of the transition state. A similar study in related compounds without the OH group showed no effect of chain length on the rate of the C - H insertion reaction. A related study of the epoxidation reaction of la also found an increased rate when chain length permitted intramolecular H-bonding by an OH group.

Methyl Group Migration in the Reactions of Alkynyltrialkylborates

It is shown that the methyl group cannot be used as a cheap, non-migrating group in the reactions of alkynyltrialkylborates with electrophiles.However, trimethylborane can be used as a methylboronating agent for alkynes, given the right choice of solvent, and this may be of use in terpene synthesis.

CH3Li/TiCl4: A NON-BASIC AND HIGHLY SELECTIVE GRIGNARD ANALOGUE

Treatment of CH3Li or CH3MgCl with TiCl4 results in quantitative formation of CH3TiCl3, a non-basic reagent which reacts chemo- and stereoselectively with carbonyl compounds.It is considerably more reactive than the alkoxy analogue CH3Ti(OCHMe2)3.This means that selective addition to ketones in the presence of such a functionality as nitro, cyano and ester groups is possible.Addition to enolizable ketones is smooth.The stereoselectivity is comparable to that observed for CH3Ti(OCHMe)3.