62557-32-8Relevant articles and documents
Synthetic method of aminothiazole compounds
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Paragraph 0085; 0098-0102, (2020/09/09)
The invention provides a synthetic method of aminothiazole compounds, and belongs to the technical field of medicine synthesis. The synthetic method comprises the following steps: step f, reacting a compound with a structure as shown in a formula (VI) with selenium dioxide to obtain a compound with a structure as shown in a formula (VII) and the like. The synthetic method of the aminothiazole compound is mainly used for synthesizing the aminothiazole compound, is easy to operate, simple in post-treatment, mild in reaction condition and high in final product yield.
2,4-Dithi(oxo)-pyrimidin-5-yl compounds bearing a tricyclic substituent useful as P2 purinoceptor antagonists
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, (2008/06/13)
PCT No. PCT/SE98/01240 Sec. 371 Date Sep. 30, 1998 Sec. 102(e) Date Sep. 30, 1998 PCT Filed Jun. 25, 1998 PCT Pub. No. WO99/02501 PCT Pub. Date Jan. 21, 1999The invention relates to new pharmaceutically active compounds which are P2-purinoceptor 7-transmembrane (TM) G-protein coupled receptor antagonists, compositions containing them and processes for their preparation.
Thiazolo[3,4-b]isoquinolines
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, (2008/06/13)
Isoquinoline derivatives of the formula STR1 wherein the symbol A1 represents an isoquinol-8-yl, 3-methylisoquinol-8-yl, 3-hydroxymethylisoquinol-5-yl, 3-carboxymethylisoquinol-5-yl, quinol-5-yl, thienopyridyl, benzimidazolyl, thienyl or thiazolyl radical, a 4-(or 5-)carboxyalkylthiazol-2-yl radical in which the alkyl moiety is linear or branched and contains 1 to 4 carbon atoms, or a 1,3,4-thiadiazol-2-yl, pyrazolyl, imidazolyl, pyrimidinyl, pyridazinyl or pyrazinyl radical, monocyclic heterocyclic rings within the definition of A1 being optionally substituted by a linear or branched alkyl radical containing 1 to 4 carbon atoms, in the (S) or (R,S) form or mixtures thereof, and salts thereof possess useful pharmocological properties, in particular antiviral activity.