62574-33-8

Upstream product

• 33064-14-1 4-benzoyl-3-methyl-1-phenylpyrazol-5-one 
• 4551-69-3 4-benzoyl-1-phenyl-3-methyl-2-pyrazolin-5-one 
• 89-25-8 edaravone 
• 98-88-4 benzoyl chloride 
• 37703-78-9 (5-benzoyloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-phenyl-methanone 
• 10025-87-3 trichlorophosphate 
• 64598-48-7 4-Benzoyl-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 
• 1131-17-5 5-chloro-3-methyl-1-phenyl-1H-pyrazole 

Downstream Products

• 79071-33-3 4-benzoyl-3-methyl-1-phenyl-2-pyrazoline-5-thione 
• 412327-01-6 [5-(3,5-dichloro-phenylsulfanyl)-3-methyl-1-phenyl-1H-pyrazol-4-yl]-phenyl-methanone 
• 412325-70-3 [5-(3,5-dichlorophenylthio)-3-methyl-1-phenyl-1H-pyrazol-4-yl]-phenyl-methanol 
• 133175-91-4 Dimethyl-(3-methyl-1,4-diphenyl-1H-pyrazolo[3,4-b]quinolin-6-yl)-amine 
• 118619-09-3 C₄₆H₃₆N₆S₂ 
• 118619-08-2 C₃₇H₃₄N₆S₂ 
• 118619-07-1 C₃₆H₃₂N₆S₂ 
• 118619-03-7 4-[1-(2-Amino-phenylamino)-1-phenyl-meth-(Z)-ylidene]-5-methyl-2-phenyl-2,4-dihydro-pyrazole-3-thione 
• 118619-04-8 4-[1-(4-Amino-phenylamino)-1-phenyl-meth-(Z)-ylidene]-5-methyl-2-phenyl-2,4-dihydro-pyrazole-3-thione 
• 57784-94-8 5-Methyl-2-phenyl-4-[1-phenyl-1-phenylamino-meth-(Z)-ylidene]-2,4-dihydro-pyrazole-3-thione 
• 118619-01-5 4-[1-(N',N'-Dimethyl-hydrazino)-1-phenyl-meth-(Z)-ylidene]-5-methyl-2-phenyl-2,4-dihydro-pyrazole-3-thione 
• 118619-02-6 4-[1-Hydroxyamino-1-phenyl-meth-(Z)-ylidene]-5-methyl-2-phenyl-2,4-dihydro-pyrazole-3-thione 
• 383909-73-7 bis(1-phenyl-3-methyl-4-benzoylpyrazolyl-5)diselenide 
• 879567-81-4 4,5-dichloro-3-methyl-1-phenyl-1H-pyrazole 

Relevant academic research and scientific papers

Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells

Immune thrombocytopenia (ITP) is caused by production of an autoantibody to autologous platelets. ITP can be treated either by reducing platelet destruction or by increasing platelet production. Fcγ receptor mediated phagocytosis of the opsonized blood ce

Anti-HIV pyrazole derivatives

The present invention comprises novel and known pyrazole derivatives having anti-HIV activity, a process for their manufacture, pharmaceutical compositions and the use of such compounds in medicine. In particular, the compounds of formula I are inhibitors

Synthesis of substituted 3-phenyl-6H-pyrazolo[4,3-d]isoxazoles from corresponding 4-benzoyl-5-hydroxypyrazoles

Treatment of 1,(3)-(di)substituted 4-benzoyl-5-hydroxypyrazoles with phosphorus oxychloride affords the corresponding 4-benzoyl-5-chloropyrazoles. Reaction of the latter with hydroxylamine leads to oximes, which can be cyclized to novel 3-phenyl-6H-pyrazolo[4,3-d]isoxazoles by treatment with sodium hydride in dimethyl formamide. Detailed nmr spectroscopic studies (1H, 13C) with all obtained compounds are presented.