6280-00-8

Basic information

• Product Name: 1,6-bis(4-methylphenyl)hexane-1,6-dione
• CAS NO: 6280-00-8
• Molecular Formula: C₂₀H₂₂O₂
• Molecular Weight: 294.3875
• Mol File: 6280-00-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 466°C at 760 mmHg
• Flash Point: 173.3°C
• Density: 1.055g/cm³
• Vapor Pressure: 7.35E-09mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 1,6-bis(4-methylphenyl)hexane-1,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-bis(4-methylphenyl)hexane-1,6-dione(6280-00-8)
• EPA Substance Registry System: 1,6-bis(4-methylphenyl)hexane-1,6-dione(6280-00-8)

Safety Data

• Hazardous Substances Data: 6280-00-8(Hazardous Substances Data)

Usage

Type of compound

Diketone

Common uses

Synthesis of various organic compounds
Production of fragrances
Production of dyes
Production of pharmaceuticals

Applications

Building block in the synthesis of polymers
Building block in the synthesis of other organic materials

Aromatic properties

Known for its aromatic properties

Research and development

Used in research and development laboratories for its unique chemical properties and potential applications in various industries.

Upstream product

• 40122-37-0 1-(p-tolyl)cyclopropan-1-ol 
• 124-04-9 Adipic acid 
• 19832-78-1 1-(4-methylphenyl)prop-2-en-1-one 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 917-57-7 vinyllithium 
• 99260-47-6 4,4'-(octa-1,7-diene-2,7-diyl)bis(methylbenzene) 
• 116385-37-6 ((Z)-3-Iodo-1-p-tolyl-propenyloxy)-trimethyl-silane 
• 111-50-2 Adipic acid dichloride 
• 108-88-3 toluene 

Downstream Products

• 104-85-8 para-methylbenzonitrile 
• 99260-47-6 4,4'-(octa-1,7-diene-2,7-diyl)bis(methylbenzene) 
• 71225-01-9 2,5-dibromo-1,6-di-p-tolyl-hexane-1,6-dione 
• 124778-32-1 1,6-di(p-tolyl)hexane 

Relevant articles and documents

Cobalt(II)-Catalyzed Stereoselective Olefin Isomerization: Facile Access to Acyclic Trisubstituted Alkenes

Stereoselective synthesis of trisubstituted alkenes is a long-standing challenge in organic chemistry, due to the small energy differences between E and Z isomers of trisubstituted alkenes (compared with 1,2-disubstituted alkenes). Transition metal-catalyzed isomerization of 1,1-disubstituted alkenes can serve as an alternative approach to trisubstituted alkenes, but it remains underdeveloped owing to issues relating to reaction efficiency and stereoselectivity. Here we show that a novel cobalt catalyst can overcome these challenges to provide an efficient and stereoselective access to a broad range of trisubstituted alkenes. This protocol is compatible with both mono- and dienes and exhibits a good functional group tolerance and scalability. Moreover, it has proven to be a useful tool to construct organic luminophores and a deuterated trisubstituted alkene. A preliminary study of the mechanism suggests that a cobalt-hydride pathway is involved in the reaction. The high stereoselectivity of the reaction is attributed to both a π-πstacking effect and the steric hindrance between substrate and catalyst.

One-pot synthesis and characterization of some new types of 5,5′-disubstituted bis(imidazolidine-2,4-diones)

The synthesis and structural elucidation of some novel 5,5′- disubstituted spiro and nonspiro-bis-hydantoins are reported. The Bucherer Burge's method has been modified for the preparation of some 5,5′-substituted bis(imidazolidine-2,4-dione) derivatives starting with diketones (1-5) and dialdehydes (6, 7). In some cases, diastereoisomeric mixtures of compounds were obtained. The resulting bis-hydantoins (8-11, 13, 14) have not to our knowledge been previously reported in the literature.

Photoinduced Electron Transfer (PET) cyclization and photooxygenation of 2,6-diaryl-1,6-heptadienes and 2,7-diaryl-1,7-octadienes

The 2,6-diaryl-substituted 1,6-heptadienes 3a-c and the 2,7-diaryl-substituted 1,7-octadienes 4a-b were cleanly converted into the corresponding anellated cyclobutanes 5 and 6, resp., when irradiated under photoelectron-transfer conditions (9,10-dicyanoanthracene in acetonitrile). Only for 4c did the rearranged compound 7c become the dominant photoproduct. Oxygen trapping experiments with formation of endoperoxides 8, 9 were successful in the case of the electron-rich substrates 3b, c and 4c. VCH Verlagsgesellschaft mbH, 1996.