6292-08-6

Basic information

• Product Name: (2Z)-N,N-diethyl-3-phenylbut-2-enamide
• CAS NO: 6292-08-6
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.3068
• Mol File: 6292-08-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 362.8°C at 760 mmHg
• Flash Point: 163.1°C
• Density: 0.984g/cm³
• Vapor Pressure: 1.88E-05mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: (2Z)-N,N-diethyl-3-phenylbut-2-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-N,N-diethyl-3-phenylbut-2-enamide(6292-08-6)
• EPA Substance Registry System: (2Z)-N,N-diethyl-3-phenylbut-2-enamide(6292-08-6)

Safety Data

• Hazardous Substances Data: 6292-08-6(Hazardous Substances Data)

Usage

General Description

"(2Z)-N,N-diethyl-3-phenylbut-2-enamide" is a chemical compound with the molecular formula C16H21NO. It is a butenamide, which is a derivative of butyric acid. (2Z)-N,N-diethyl-3-phenylbut-2-enamide is a yellowish to light-brown liquid and is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It has potential applications in the pharmaceutical industry as an antifungal agent. The compound has two ethyl groups attached to the nitrogen atom, a phenyl group attached to the double bond, and a trans configuration in the double bond. It is important to handle this chemical with care and be aware of its potential hazards.

Upstream product

• 2315-36-8 2-Chloro-N,N-diethylacetamide 
• 201230-82-2 carbon monoxide 
• 109-89-7 diethylamine 
• 98-86-2 acetophenone 
• 945-93-7 ethyl (E)-3-phenylbut-2-enoate 
• 704-80-3 (E)-3-phenyl-2-butenoic acid 
• 16917-35-4 (E)-(1-bromoprop-1-en-2-yl)benzene 
• 64-18-6 formic acid 
• 3699-76-1 diethyl <(diethylcarbamoyl)methyl>phosphonate 

Downstream Products

• 30069-65-9 3-phenylnaphthalen-1-ol 
• 106914-45-8 3-phenyl-5,8-dimethoxynaphth-1-ol 
• 106914-44-7 6,8-Dimethoxy-3-phenyl-naphthalen-1-ol 

Relevant articles and documents

Electron-Catalyzed Aminocarbonylation: Synthesis of α,β-Unsaturated Amides from Alkenyl Iodides, CO, and Amines

Aminocarbonylation of alkenyl iodides with CO and amines proceeded under heating to produce α,β-unsaturated amides in good yields (23 examples, 71% average yield). This catalyst-free method exhibited good functional-group tolerance, and open a straightforward access to functionalized acrylamides, as illustrated by the synthesis of Ilepcimide. A hybrid radical/ionic mechanism involving chain electron transfer is proposed for this transformation.

Enantioselective epoxidation of β,β-disubstituted enamides with a manganese catalyst and aqueous hydrogen peroxide

Enantioselective epoxidation of β,β-disubstituted enamides with aqueous hydrogen peroxide and a novel manganese catalyst is described. Epoxidation is stereospecific and proceeds fast under mild conditions. Amides are disclosed as key functional groups to enable high enantioselectivity.

Reaction of lithiated senecioamide and related compounds with benzynes: Efficient syntheses of naphthols and naphthoquinones

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