6301-08-2

Basic information

• Product Name: propan-2-yl piperidine-1-carboxylate
• Synonyms: 1-Piperidinecarboxylic acid, isopropyl ester
• CAS NO: 6301-08-2
• Molecular Formula: C₉H₁₇NO₂
• Molecular Weight: 171.2368
• Mol File: 6301-08-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 231°C at 760 mmHg
• Flash Point: 93.5°C
• Density: 1.016g/cm³
• Vapor Pressure: 0.0637mmHg at 25°C
• Refractive Index: 1.467
• CAS DataBase Reference: propan-2-yl piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: propan-2-yl piperidine-1-carboxylate(6301-08-2)
• EPA Substance Registry System: propan-2-yl piperidine-1-carboxylate(6301-08-2)

Safety Data

• Hazardous Substances Data: 6301-08-2(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 35180-01-9 chloromethyl isopropyl carbonate 
• 108-23-6 isopropyl chloroformate 
• 201230-82-2 carbon monoxide 
• 67-63-0 isopropyl alcohol 
• 124-38-9 carbon dioxide 
• 75-26-3 isopropyl bromide 

Relevant articles and documents

Oxidations of pyrrolidines and piperidines to afford CH-functionalized isopropyl-1-carboxylate congeners

This article describes the action of iodine(III) reagents [diacetoxyiodobenzene, PhI(OAc)2, and iodosobenzene, (PhIO)n] in conjunction with TMSBr which act as functional bromine equivalents in unique oxidations of saturated, carbamate protected N-heterocycles. Interestingly, during this work, treatment of the same carbamates with molecular bromine alone afforded similar products, which were sequestered by the solvent methanol.

α-Haloalkyl Haloformates and Related Compounds 1. A Convenient Synthesis of Carbamates via Chloromethyl Carbamates

The preparation of carbamates under mild conditions utilizing a new class of activated carbonates (containing chloromethyl function) is described.