63329-72-6

Basic information

• Product Name: Benzo[b]thiophen-3(2H)-one, 2-(phenylmethylene)-, (Z)-
• CAS NO: 63329-72-6
• Molecular Formula: C15H10OS
• Molecular Weight: 238.31
• Mol File: 63329-72-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzo[b]thiophen-3(2H)-one, 2-(phenylmethylene)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[b]thiophen-3(2H)-one, 2-(phenylmethylene)-, (Z)-(63329-72-6)
• EPA Substance Registry System: Benzo[b]thiophen-3(2H)-one, 2-(phenylmethylene)-, (Z)-(63329-72-6)

Safety Data

• Hazardous Substances Data: 63329-72-6(Hazardous Substances Data)

Upstream product

• 1311381-55-1 (E)-1-(2-(methylthio)phenyl)-3-phenylprop-2-en-1-one 
• 1441-97-0 2'-(methylthio)acetophenone 
• 100-52-7 benzaldehyde 
• 2142-69-0 2-bromophenyl methyl ketone 
• 130-03-0 thioindoxyl 
• 103-04-8 (phenylthio)acetic acid 
• 7031-27-8 (phenylthio)acetic acid chloride 
• 493-57-2 benzo-[b]thiophene-2,3-dione 
• 147-93-3 Thiosalicylic acid 
• 1531-80-2 2-(benzylthio)benzoic acid 
• 16619-38-8 2'-nitro-chalcone 
• 62786-15-6 2-benzylidene-1-benzothiophen-3(2H)-one 
• 4892-02-8 Methyl thiosalicylate 
• 117968-39-5 1-[2-(4-methoxybenzylthio)phenyl]-2-(methylsulfinyl)ethanone 

Downstream Products

• 25625-01-8 thioaurone 1,1-dioxide 
• 62786-15-6 2-benzylidene-1-benzothiophen-3(2H)-one 

Relevant articles and documents

Access to Spirocyclic Benzothiophenones with Multiple Stereocenters via an Organocatalytic Cascade Reaction

The present report describes an organocatalytic cascade reaction between 2-alkylidene benzo[b]thiophenone derivatives and enones in the presence of the Cinchona alkaloid amine. Spirobenzothiophenonic cyclohexane derivatives containing three stereocenters were prepared via one-step synthesis in yields ranging from 88 to 96% and in enantioselectivities (enantiomeric excess (ee)) ranging from 85 to 97%, with diastereoselectivities of approximately 14/2/1. Therefore, this method provides an efficient route for the synthesis of a new class of optically active 2-spirobenzothiophenones.

METHOD FOR SYNTHESIZING THIOAURONES

An embodiment of the present invention is a process for producing 2 - benzoic acid compound by reacting a thiosalicylic acid with a strongly basic substance and a benzylhalide. The 2 - methoxy - N N-methyl -2 - benzamides, which are reacted with N - methoxy - N N-methylcarbamoyl chloride to produce N - methoxy-N-methylbenzamides. The N - methoxy - N N-methyl -2 - (benzocyclohexyl) benzamide is treated with arylethynyl salt to prepare 1 - (2- benzocyclohexyl) phenyl -3 - phenyl -2 - profin -1 . The 1 - (2-) phenyl -3 - phenyl -2 - profin -1 - one is treated with an acid material. Provided is a method for preparing a thiouronone compound.

Cooperative Activating Effect of Tertiary Amine/DMSO on Elemental Sulfur: Direct Access to Thioaurones from 2′-Nitrochalcones under Mild Conditions

A new mode for the activation of elemental sulfur is reported. In the presence of both DMSO and a tertiary aliphatic amine (triethylamine or N-methylpiperidine), this element reacts directly with a wide range of 2′-nitrochalcones 1 to provide the corresponding thioaurones 2 in high yields even at room temperature and in the absence of transition metal catalyst.