6337-68-4

Upstream product

• 17734-38-2 ethyl 5-phenylpentanoate 
• 75-36-5 acetyl chloride 
• 41302-32-3 ethyl 5-iodopentanoate 
• 99-90-1 para-bromoacetophenone 
• 109976-46-7 (5-ethoxy-5-oxopentyl)zinc(II) iodide 
• 14660-52-7 ethyl 5-bromovalerate 
• 13329-40-3 4-Iodoacetophenone 

Downstream Products

• 89326-68-1 5-(4-acetyl-phenyl)-valeric acid 

Relevant academic research and scientific papers

Direct synthesis of ester-containing indium homoenolate and its application in palladium-catalyzed cross-coupling with aryl halide

An efficient method for the synthesis of ester-containing indium homoenolate via a direct insertion of indium into β-halo ester in the presence of CuI/LiCl was described. The synthetic utility of the indium homoenolate was demonstrated by palladium-cataly

One-step cross-coupling reaction of functionalized alkyl iodides with aryl halides by the use of an electrochemical method

Organozinc compounds of functionalized alkyl iodide carrying an alkoxycarbonyl, cyano or alkenyl group were prepared in high yields under mild conditions (0°C-r.t., 10min in DMF) by the reaction of iodides with an electrogenerated reactive zinc (EGZn). Cross-coupling of the organozinc compounds with various aryl halides in the presence of 5 mol% Pd(P(o- Tol)3)2Cl2 in THF gave the corresponding cross-coupled products in moderate to high yields. These cross-coupling reactions can be also achieved in one step and in one pot by the use of an electrochemical method utilizing a Pt cathode and Zn anode.