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2-Nitro-1-phenylpropan-1-ol, also known as 2-nitro-1-phenylpropanol or 2-nitropropiophenone, is an organic compound with the chemical formula C9H11NO3. It is a yellow crystalline solid that is soluble in organic solvents and has a molecular weight of 181.19 g/mol. 2-nitro-1-phenylpropan-1-ol is characterized by the presence of a nitro group (-NO2) at the 2-position, a phenyl group (C6H5) at the 1-position, and a hydroxyl group (-OH) at the 1-position as well. It is used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. Due to its reactivity and potential applications, 2-nitro-1-phenylpropan-1-ol is a subject of interest in the field of organic chemistry.

6343-57-3

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6343-57-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6343-57-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,4 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6343-57:
(6*6)+(5*3)+(4*4)+(3*3)+(2*5)+(1*7)=93
93 % 10 = 3
So 6343-57-3 is a valid CAS Registry Number.

6343-57-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-nitro-1-phenylpropan-1-ol

1.2 Other means of identification

Product number -
Other names 1-phenyl-2-nitropropan-1-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6343-57-3 SDS

6343-57-3Relevant academic research and scientific papers

Copper complexes of 1,4-diazabutadiene ligands: Tuning of metal oxidation state and, application in catalytic C-C and C-N bond formation

Mukherjee, Aparajita,Basu, Semanti,Bhattacharya, Samaresh

, (2019/11/11)

Reaction of 1,4-diazabutadiene (p-RC6H4N = C(H)(H)C = NC6H4R-p; R = OCH3, CH3, H and Cl; abbreviated as L-R) with CuCl2·2H2O in methanol at ambient temperature (25 °C) affords a group of doubly chloro-bridged dicopper complexes of type [{CuI(L-R)Cl}2], designated as 1-R. Similar reaction carried out in acetonitrile furnishes a family of doubly chloro-bridged dicopper complexes of type [{CuII(L-R)Cl2}2], designated as 2-R. Molecular structures of 1-OCH3 and 2-OCH3 have been determined by X-ray crystallography. While copper(I) is having a nearly tetrahedral N2Cl2 coordination sphere in 1-OCH3, the N2Cl3 coordination sphere around copper(II) is distorted square pyramidal in nature in 2-OCH3. Isolated 2-R complexes, on dissolution in methanol, are found to undergo facile reduction of the metal center to generate the corresponding 1-R complexes. The 1-R and 2-R complexes show intense absorptions in the visible and ultraviolet regions. Cyclic voltammetry on the 1-R and 2-R complexes shows both metal-centered and ligand centered redox responses. The 1-R complexes are found to efficiently catalyze C-N cross-coupling reactions between arylboronic acids and aryl amines; while the 2-R complexes display notable catalytic efficiency for nitroaldol reactions.

Designing of a magnetically separable Fe3O4@dopa@ML nano-catalyst for multiple organic transformations (epoxidation, reduction, and coupling) in aqueous medium

Dasgupta, Sanchari,Chatterjee, Sourav,Chattopadhyay, Tanmay

, p. 550 - 568 (2019/02/26)

A copper(II) macrocyclic Schiff base complex (ML) was synthesized by condensation between 2,2-dimethylpropane-1,3-diammine and 2,6-diformyl-4-butylphenol with the aim to modify the surface of widely used magnetically separable nanocatalyst Fe3O

Ultrasound-assisted synthesis of two new fluorinated metal-organic frameworks (F-MOFs) with the high surface area to improve the catalytic activity

Joharian, Monika,Morsali, Ali

, p. 135 - 146 (2018/11/24)

Micro- and nano-structures of two zinc(II) based fluorinated metal-organic frameworks (F-MOFs) [Zn2(hfipbb)2(4-bpdh)].(DMF)0.5 (TMU-55) and [Zn2(hfipbb)2(4-bpdb)].(DMF)2 (HTMU-55) with micr

Preparation of diverse BODIPY diesters

Abeywardana, Sewwandi,Cantu, Annabelle L.,Nedic, Teodora,Schramm, Michael P.

, p. 3393 - 3396 (2018/08/17)

The synthesis and properties of a variety of substituted BODIPY diesters is presented. We find that certain substitution patterns afford appreciable yields of the target compounds and that electronic effects result in predicable differential fluorescent behavior. Challenges to further water solubilize these dyes and/or provide new points of attachment for biological tagging remain, these strategies are discussed.

D-Mannitol-derived novel chiral thioureas: Synthesis and application in asymmetric Henry reactions

Liu, Miaoxi,Ji, Nan,Wang, Li,Liu, Peng,He, Wei

, p. 999 - 1004 (2018/02/23)

Five novel thioureas have been obtained through multi-step reactions from D-Mannitol as starting material and applied as catalysts in the asymmetric Henry reaction. Using catalyst 7a, (1S,2R)-2-nitro-1-phenylpropan-1-ol containing two chiral centers was o

A nitroaryloxy aromatic preparation method (by machine translation)

-

Paragraph 0109; 0110; 0111; 0112; 0113, (2017/05/23)

The invention discloses a nitroaryloxy aromatic preparation method, comprises the following steps: a, will R1 CHO, R2 CH2 NO2 , Catalyst and a polar organic solvent evenly, 0 °C -40 °C stirring for 6 hours -48 h

A amide preparation method of the compound

-

Paragraph 0115; 0116; 0117; 0118, (2017/06/02)

The invention discloses a preparation method for an amide compound. The method comprises the steps of: a. taking R1CHO and R2CH2NO2, adding a catalyst and R3CN, carrying out stirring reaction for 24h-48h at 0DEG C-40DEG C to obtain a reaction liquid; and

Solvent-Free Henry and Michael Reactions with Nitroalkanes Promoted by Potassium Carbonate as a Versatile Heterogeneous Catalyst

Bosica, Giovanna,Polidano, Kurt

, (2017/07/11)

The use of a simple weak inorganic base such as potassium carbonate facilitated the formation of carbon-carbon bonds through both the Henry and the Michael reactions with nitrocompounds. The application of this catalyst under environmentally friendly solventless heterogeneous conditions gave satisfactory to good yields of β-nitroalcohols, involving aliphatic and aromatic starting materials, as well as high to excellent yields in the formation of Michael adducts using several different Michael acceptors and nitroalkanes.

Henry reaction catalyzed by recyclable [C4dabco]OH ionic liquid

Keithellakpam, Sanjoy,Laitonjam, Warjeet S.

, p. 110 - 113 (2016/02/26)

DABCO-based ionic liquid, 1-butyl-4-aza-1-azaniabicyclo[2.2.2]octane hydroxide, has been used as an efficient catalyst for Henry reaction of various carbonyl compounds with nitroalkanes affording very high yields within a short duration. This method is very simple, clean and avoids hazardous organic solvents. The catalyst can be easily recovered and recycled several times.

Henry reaction catalyzed by recyclable [C4dabco]OH ionic liquid

Keithellakpam, Sanjoy,Laitonjam, Warjeet S.

, p. 110 - 113 (2017/01/18)

DABCO-based ionic liquid, 1-butyl-4-aza-1-azaniabicyclo[2.2.2]octane hydroxide, has been used as an efficient catalyst for Henry reaction of various carbonyl compounds with nitroalkanes affording very high yields within a short duration. This method is very simple, clean and avoids hazardous organic solvents. The catalyst can be easily recovered and recycled several times.

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