6375-16-2

Basic information

• Product Name: N-(3-amino-4-methylphenyl)acetamide
• Synonyms: N-(3-amino-4-methylphenyl)acetamide;4-acetylamino-2-aminotoluene;3'-Amino-p-acetotoluidide;5-Acetylamino-o-toluidine;N-(3-amino-4-methylphenyl)acetamide(SALTDATA: FREE)
• CAS NO: 6375-16-2
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.20438
• EINECS: 228-933-0
• Mol File: 6375-16-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 645.4°C at 760 mmHg
• Flash Point: 213.5°C
• Appearance: /
• Density: 1.109g/cm³
• Vapor Pressure: 1.52E-16mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: N-(3-amino-4-methylphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-amino-4-methylphenyl)acetamide(6375-16-2)
• EPA Substance Registry System: N-(3-amino-4-methylphenyl)acetamide(6375-16-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• RTECS: AD8580000
• HazardClass: IRRITANT
• Hazardous Substances Data: 6375-16-2(Hazardous Substances Data)

Usage

General Description

N-(3-amino-4-methylphenyl)acetamide, also known as N-Acetyl-3-amino-4-methylbenzeneamine, is an organic compound with the chemical formula C9H12N2O. It is a white to off-white solid that is used in the synthesis of pharmaceuticals and other organic compounds. N-(3-amino-4-methylphenyl)acetamide is a member of the acetamide class of compounds, which are commonly used as intermediates in the production of various pharmaceuticals, agrochemicals, and other organic products. It is also used as a reagent in organic synthesis and is known for its mild and selective reaction conditions. The compound has potential applications in fields such as medicine, drug development, and chemical research.

InChI:InChI=1/C23H26N2O2/c1-23(2,17-24-21(26)15-13-19-9-5-3-6-10-19)18-25-22(27)16-14-20-11-7-4-8-12-20/h3-16H,17-18H2,1-2H3,(H,24,26)(H,25,27)

Upstream product

• 121-14-2 2,4-dinitrotoluene 
• 95-80-7 4-methylbenzene-1,3-diamine 
• 64-19-7 acetic acid 
• 119-32-4 4-Methyl-3-nitroanilin 
• 2719-14-4 4-acetylamino-2-nitrotoluene 
• 60-35-5 acetamide 

Downstream Products

• 35435-49-5 6-methyl-benzothiazole-2,5-diyldiamine 
• 5307-07-3 3-hydroxy-4-methylacetanilide 
• 33856-94-9 N-{3-[(N-Hydroxy-2-oxo-propionimidoyl)-amino]-4-methyl-phenyl}-acetamide 
• 19593-77-2 4-Acetylamino-2-vinylsulfamido-toluol 
• 144630-79-5 N-(8-Methyl-4-phenyl-quinolin-5-yl)-acetamide 
• 47000-92-0 flubendiamide 
• 726192-64-9 6-methyl-N-(pyrimidin-2-yl)benzene-1,3-diamine hydrochloride 
• 88318-05-2 1-amino-4-(5'-amino-2'-methylphenylamino)-anthraquinone-2-sulphonic acid 
• 19593-78-3 4-Amino-2-vinylsulfamido-toluol 
• 109565-24-4 (5-amino-2-methyl-phenyl)-(4-dimethylamino-phenyl)-diazene 

Relevant articles and documents

Aryl imidazole derivative and application thereof

The invention relates to an aryl imidazole derivative and application thereof. The aryl imidazole derivative is a compound shown as a formula (I) in the description or pharmaceutically acceptable salt thereof. The invention also discloses application of the aryl imidazole derivative in preparation of drugs for treating cancers. The invention further discloses application of the aryl imidazole derivative in preparation of drugs for treating diseases caused by EGFR mutation.

N-heterocyclic inhibitors of TNF-alpha expression

N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

Phthalocyanine reactive dyestuffs

Phthalocyanine reactive dyestuffs which, in the form of the free acid, have the formula (1) STR1 in which the variable radicals have the meaning given in the description, are prepared by condensation of the corresponding amines with cyanuric fluoride or cyanuric chloride in any desired order. The reactive dyestuffs according to the invention exhibit good wet and light fastness properties and are used for the dyeing and printing of cotton.