6375-16-2

Usage

Uses

Used in Pharmaceutical Synthesis:
N-(3-amino-4-methylphenyl)acetamide is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new medications and improve existing ones.
Used in Agrochemical Production:
N-(3-amino-4-methylphenyl)acetamide is also utilized as an intermediate in the production of agrochemicals, playing a role in the creation of products that contribute to agricultural advancements.
Used in Organic Synthesis:
N-(3-amino-4-methylphenyl)acetamide serves as a reagent in organic synthesis, where its mild and selective reaction conditions are advantageous for specific chemical reactions.
Used in Chemical Research:
N-(3-amino-4-methylphenyl)acetamide is employed in chemical research to explore new chemical reactions and develop innovative applications in various fields, including medicine and drug development.

InChI:InChI=1/C23H26N2O2/c1-23(2,17-24-21(26)15-13-19-9-5-3-6-10-19)18-25-22(27)16-14-20-11-7-4-8-12-20/h3-16H,17-18H2,1-2H3,(H,24,26)(H,25,27)

Upstream product

• 60-35-5 acetamide 
• 95-80-7 4-methylbenzene-1,3-diamine 
• 2719-14-4 4-acetylamino-2-nitrotoluene 
• 64-19-7 acetic acid 
• 121-14-2 2,4-dinitrotoluene 
• 119-32-4 4-Methyl-3-nitroanilin 

Downstream Products

• 35435-49-5 6-methyl-benzothiazole-2,5-diyldiamine 
• 5307-07-3 3-hydroxy-4-methylacetanilide 
• 33856-94-9 N-{3-[(N-Hydroxy-2-oxo-propionimidoyl)-amino]-4-methyl-phenyl}-acetamide 
• 144630-79-5 N-(8-Methyl-4-phenyl-quinolin-5-yl)-acetamide 
• 144630-81-9 8-Methyl-4-phenyl-quinolin-5-ylamine 
• 144630-83-1 5-Azido-8-methyl-4-phenyl-quinoline 
• 88318-05-2 1-amino-4-(5'-amino-2'-methylphenylamino)-anthraquinone-2-sulphonic acid 
• 47000-92-0 flubendiamide 
• 726192-64-9 6-methyl-N-(pyrimidin-2-yl)benzene-1,3-diamine hydrochloride 
• 19593-78-3 4-Amino-2-vinylsulfamido-toluol 
• 109565-24-4 (5-amino-2-methyl-phenyl)-(4-dimethylamino-phenyl)-diazene 

Relevant academic research and scientific papers

Aryl imidazole derivative and application thereof

The invention relates to an aryl imidazole derivative and application thereof. The aryl imidazole derivative is a compound shown as a formula (I) in the description or pharmaceutically acceptable salt thereof. The invention also discloses application of the aryl imidazole derivative in preparation of drugs for treating cancers. The invention further discloses application of the aryl imidazole derivative in preparation of drugs for treating diseases caused by EGFR mutation.

N-heterocyclic inhibitors of TNF-α expression

N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

N-heterocyclic inhibitors of TNF-alpha expression

N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

N- heterocyclic inhibitors of TNF-alpha expression

N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

Phthalocyanine reactive dyestuffs

Phthalocyanine reactive dyestuffs which, in the form of the free acid, have the formula (1) STR1 in which the variable radicals have the meaning given in the description, are prepared by condensation of the corresponding amines with cyanuric fluoride or cyanuric chloride in any desired order. The reactive dyestuffs according to the invention exhibit good wet and light fastness properties and are used for the dyeing and printing of cotton.

Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member

A reactive dye of the formula STR1 in which: F is a radical selected from the group consisting of metal-free or metal-containing monoazo or disazo dyes containing at least one --SO3 H group, anthraquinone dyes, sulfophthalocyanine dyes, formazan dyes, phenazine dyes, oxazine dyes and nitroaryl dyes, R is hydrogen, C1 -C4 alkyl which is unsubstituted or substituted with --COOH or --SO3 H, cyanoethyl, or hydroxyethyl, X is fluorine, chlorine, bromine, --SO3 H, phenylsulfonyl or C1 -C4 -alkylsulfonyl, p is 1 or 2 and A is a radical of the formula STR2 in which: Y is chlorine, bromine, fluorine, --OH, --OSO3 H, --O-acyl, --CN, --COOH, --COO--C1 -C4 -alkyl, --CONH2 or --SO2 --Z, the group designated "alk" is a straight or branched polymethylene radical having 2 to 6 carbon atoms, V is STR3 hydrogen or C1 -C4 -alkyl which is unsubstituted or substituted by C1 -C2 -alkoxy, carboxyl, sulfo, halogen or hydroxy, Z is β-halogenoethyl, vinyl or β-acetoxyethyl, or A is a radical of the formulae STR4 in all of which R' is C1-6 -alkyl or hydrogen, Z is as defined above, o is 0 to 6, and m is 2 to 6.

Bisazo brown reactive dye

A brown reactive dye represented by a free acid of the formula, STR1 wherein R is a hydrogen atom or a C1 to C4 alkyl group, X is --SO2 CH2 CH2 Cl, --SO2 CH=CH2, --SO2 CH2 CH2 OSO3 H or --SO2 CH2 CH2 OPO3 H2, rings A, B and C are each a benzene or naphthalene ring which may have other substituent, m is 0 to 3 and n is 0 to 1. This dye is suitable for dyeing cellulose fibers brown to afford dyeings superior in fastnesses, acid stability, build-up property and level dyeing property.

Fiber-reactive disazo brown dye having vinylsulfone-type reactive group

A compound, or a salt thereof, represented by the following formula, STR1 wherein A is a substituted or unsubstituted phenylene or naphthylene group, B is STR2 in which R3 is a hydrogen atom or a lower alkyl, lower alkoxy, acylamino or ureido group, and R4 is a hydrogen atom or a lower alkyl or lower alkoxy group, R1 and R3 are independently a hydrogen atom or a substituted or unsubstituted lower alkyl group, X is a substituted or unsubstituted amino, lower alkoxy, substituted phenoxy or sulfo group, Y is --SO2 CH=CH2 or --SO2 CH2 CH2 Z, in which Z is a group capable of being split by the action of an alkali, and m is 2 or 3, which is useful for dyeing hydroxyl group- or amide group-containing fiber materials to give dyed products of a brown color having excellent fastness properties with good build-up property.