63874-99-7

Basic information

• Product Name: 1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde
• Synonyms: 1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde;1H-pyrazole-4-carboxaldehyde, 1-(4-chlorophenyl)-;Albb-009326;1-(p-chlorophenyl)-pyrazole-4-carboxaldehyde;1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE);1-(4-chlorophenyl)-1H-pyrazole-4-carboxaldehyde;1-(4-Chlorophenyl)pyrazole-4-carbaldehyde
• CAS NO: 63874-99-7
• Molecular Formula: C₁₀H₇ClN₂O
• Molecular Weight: 206.63
• Mol File: 63874-99-7.mol
• Article Data: 12

Chemical Properties

• Melting Point: 118 °C(Solv: ethanol (64-17-5))
• Boiling Point: 339.1°C at 760 mmHg
• Flash Point: 158.9°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 9.39E-05mmHg at 25°C
• Refractive Index: 1.623
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.85±0.10(Predicted)
• CAS DataBase Reference: 1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde(63874-99-7)
• EPA Substance Registry System: 1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde(63874-99-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 63874-99-7(Hazardous Substances Data)

Usage

General Description

1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde is a chemical compound with the molecular formula C10H7ClN2O. It is a derivative of pyrazole and contains a chlorophenyl group and a carbaldehyde group. 1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde has various potential applications in the field of organic synthesis and medicinal chemistry. It is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. Additionally, it can also be utilized as a substrate in the development of novel chemical compounds with diverse biological activities. Due to its unique structure and properties, 1-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde is a valuable and versatile compound in the field of chemical research and development.

InChI:InChI=1/C10H7ClN2O/c11-9-1-3-10(4-2-9)13-6-8(7-14)5-12-13/h1-7H

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 108-90-7 chlorobenzene 
• 35344-95-7 1H-pyrazole-4-carbaldehyde 
• 352-33-0 1-Chloro-4-fluorobenzene 
• 1073-70-7 4-chlorophenylhydrazine hydrochloride 
• 100-97-0 hexamethylenetetramine 
• 25419-86-7 1-(4-chlorophenyl)-1H-pyrazole 
• 1073-69-4 N-4-chlorophenylhydrazine 

Downstream Products

• 63875-00-3 1-(4-chloro-phenyl)-4-(4-trifluoromethyl-1⁽³⁾H-imidazol-2-yl)-1H-pyrazole 
• 1373836-36-2 2-(1-(p-chlorophenyl)pyrazol-4-yl)benzimidazole 
• 138907-80-9 1-(4-chlorophenyl)-1H-pyrazole-4-carboxylic acid 
• 1410806-35-7 1-[1-(4-Chloro-phenyl)-1H-pyrazol-4-yl]-2-piperidin-1-yl-ethanone 
• 1410806-73-3 2-chloro-1-[1-(4-chloro-phenyl)-1H-pyrazol-4-yl]-ethanone 
• 1283289-77-9 C₁₀H₆Cl₂N₂O 
• 1422960-52-8 (E)-1-(4-chlorophenyl)-4-(2-nitrovinyl)-1-phenyl-1H-pyrazole 
• 1612877-10-7 (E)-2-(2-(1-(4-chlorophenyl)-1H-pyrazol-4-yl)vinyl)quinolin-8-ol 
• 1612877-19-6 C₂₂H₁₆ClN₃O₂ 
• 1449038-88-3 3-((1-(4-chlorophenyl)-1H-pyrazol-4-yl)methoxy)propyl 4-toluenesulfonate 
• 1449038-87-2 2-((1-(4-chlorophenyl)-1H-pyrazol-4-yl)methoxy)ethyl 4-toluenesulfonate 
• 1449038-86-1 3-((1-(4-chlorophenyl)-1H-pyrazol-4-yl)methoxy)propan-1-ol 
• 1449038-85-0 2-((1-(4-chlorophenyl)-1H-pyrazol-4-yl)methoxy)ethanol 
• 1449038-84-9 4-(allyloxymethyl)-1-(4-chlorophenyl)-1H-pyrazole 

Relevant articles and documents

Electrophotocatalytic SNAr Reactions of Unactivated Aryl Fluorides at Ambient Temperature and Without Base

The electrophotocatalytic SNAr reaction of unactivated aryl fluorides at ambient temperature without strong base is demonstrated.

The novel piperazine-containing compound LQFM018: Necroptosis cell death mechanisms, dopamine D4 receptor binding and toxicological assessment

Piperazine is a promising scaffold for drug development due to its broad spectrum of biological activities. Based on this, the new piperazine-containing compound LQFM018 (2) [ethyl 4-((1-(4-chlorophenyl)-1H-pyrazol-4-yl)methyl)piperazine-1-carboxylate] wa

Induction of apoptosis in Ehrlich ascites tumour cells via p53 activation by a novel small-molecule MDM2 inhibitor – LQFM030

Objective: The activation of the p53 pathway through the inhibition of MDM2 has been proposed as a novel therapeutic strategy against tumours. A series of cis-imidazoline analogues, termed nutlins, were reported to displace the recombinant p53 protein fro