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APOCHOLIC ACID is a derivative of Cholic Acid (C432600), a choleretic agent that is produced by and isolated from liver cells. It is known for its role in promoting bile flow and aiding in the digestion and absorption of fats and fat-soluble vitamins.
Used in Pharmaceutical Industry:
APOCHOLIC ACID is used as a choleretic agent for enhancing bile flow and improving the digestion and absorption of fats and fat-soluble vitamins. It is particularly beneficial in the treatment of conditions related to impaired bile secretion and liver function.
Used in Liver Health Applications:
APOCHOLIC ACID is used as a liver support agent for promoting liver health and function. It aids in the detoxification process and helps maintain optimal liver function, which is essential for overall health and well-being.
Used in Cholesterol Management:
APOCHOLIC ACID is used as a cholesterol management agent for regulating cholesterol levels in the body. It helps in the dissolution of cholesterol gallstones and supports the body's natural cholesterol metabolism.
Used in Cosmetic Industry:
APOCHOLIC ACID is used as an ingredient in cosmetic products for its skin-friendly properties. It is known to improve skin hydration, reduce inflammation, and promote a healthy skin barrier, making it suitable for various skincare formulations.

641-81-6

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641-81-6 Usage

Safety Profile

Questionable carcinogen withexperimental tumorigenic data. When heated todecomposition it emits acrid smoke and irritating fumes.

Check Digit Verification of cas no

The CAS Registry Mumber 641-81-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,4 and 1 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 641-81:
(5*6)+(4*4)+(3*1)+(2*8)+(1*1)=66
66 % 10 = 6
So 641-81-6 is a valid CAS Registry Number.
InChI:InChI=1/C24H38O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-16,18,20-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,18-,20+,21+,23+,24-/m1/s1

641-81-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (4R)-4-[(3R,5R,9R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

1.2 Other means of identification

Product number -
Other names Apocholic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:641-81-6 SDS

641-81-6Relevant academic research and scientific papers

Synthesis, aggregation behavior and cholesterol solubilization studies of 16-epi-pythocholic acid (3α,12α,16β-trihydroxy-5β-cholan-24-oic acid)

Nonappa,Maitra, Uday

experimental part, p. 506 - 512 (2010/06/21)

Synthesis, aggregation behavior and in vitro cholesterol solubilization studies of 16-epi-pythocholic acid (3α,12α,16β-trihydroxy-5β-cholan-24-oic acid, EPCA) are reported. The synthesis of this unnatural epimer of pythocholic acid (3α,12α,16α-trihydroxy-5β-cholan-24-oic acid, PCA) involves a series of simple and selective chemical transformations with an overall yield of 21% starting from readily available cholic acid (CA). The critical micellar concentration (CMC) of 16-epi-pythocholate in aqueous media was determined using pyrene as a fluorescent probe. In vitro cholesterol solubilization ability was evaluated using anhydrous cholesterol and results were compared with those of other natural di- and trihydroxy bile acids. These studies showed that 16-epi-pythocholic acid (16β-hydroxy-deoxycholic acid) behaves similar to cholic acid (CA) and avicholic acid (3α,7α,16α-trihydroxy-5β-cholan-24-oic acid, ACA) in its aggregation behavior and cholesterol dissolution properties.

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