64209-68-3

Upstream product

• 2460-58-4 2-hydroxy-4-nitrobenzaldehyde 
• 685-87-0 Diethyl 2-bromomalonate 
• 496-41-3 Benzofuran-2-carboxylic acid 
• 96-34-4 methyl chloroacetate 
• 57356-40-8 2-(hydroxymethyl)-5-nitrophenol 
• 619-19-2 2-hydroxy-4-nitrobenzoic acid 
• 69603-99-2 6-nitrobenzofuran-2-carboxylic acid ethyl ester 

Downstream Products

• 53020-44-3 6-hydroxybenzofuran-2-carbonitrile 
• 57786-34-2 6-amino-2,3-dihydrobenzofuran 
• 110677-54-8 benzofuran-6-amine 
• 57786-33-1 6-nitrobenzofuran 

Relevant academic research and scientific papers

GLUE DEGRADERS AND METHODS OF USE THEREOF

Described herein are glue degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment or prevention of conditions, diseases, and disorders mediated by various target proteins.

SARS-COV-2 INHIBITORS HAVING COVALENT MODIFICATIONS FOR TREATING CORONAVIRUS INFECTIONS

Provided herein are compounds, pharmaceutical compositions and methods for treating a SARS-CoV-2 infection.

Pyrimidine heterocyclic compounds, pyrimidine heterocyclic compound salts, and preparation method and application thereof

The invention provides pyrimidine heterocyclic compounds, pyrimidine heterocyclic compound salts, and a preparation method and application thereof. According to the pyrimidine heterocyclic compounds provided by the invention, specific Rq is selected, so that the obtained compounds have favorable drug resistance and long half life when being used as the medicine for treating or preventing HIV. The compounds have the advantages of high activity, low toxicity and high stability.

SUBSTITUTED TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS

The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).

BENZOTHIOPHENE UREA, BENZOFURANE UREA, AND INDOLE UREA, AND USE OF THE SAME AS ALPHA-7 ACHR AGONISTS

The invention relates to novel benzothiophene urea, benzofurane urea, and indole urea, and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration power, learning capacity and/or memory retention.

Application en serie benzofurannique d'un nouveau procede de nitration par l'acide nitrique en presence de chlorure stannique

A new nitration technique, using nitric acid in the presence of stannic chloride in dichloromethane, has been extended to a series of benzofurans.The ease of performing the reaction as well as the diversity of products that can be obtained under various experimental conditions make it a worthwhile technique.