6476-52-4Relevant articles and documents
A New Approach for the Synthesis of Perfluoroalkanesulfenic Acids
Xu, Jia-Hong,Jiang, Min,Song, Li-Ping,Liu, Jin-Tao
, p. 1919 - 1923 (2021)
A new and more practical method for the preparation of solution-stable perfluoroalkanesulfenic acids was successfully developed. Starting from perfluoroalkyl iodides, perfluoroalkyl sulfoxides were synthesized by their substitution reaction with alkyl mercaptans and the following oxidation of resulting perfluoroalkyl sulfides with m-CPBA. Subsequent β-H elimination of perfluoroalkyl sulfoxides under heating conditions gave the corresponding perfluoroalkanesulfenic acids in good yields.
Approach to Comparing the Functional Group Tolerance of Reactions
Gensch, Tobias,Teders, Michael,Glorius, Frank
supporting information, p. 9154 - 9159 (2017/09/11)
Herein, we describe an approach to quantifying and comparing functional group (FG) tolerance of synthetic reactions. Additive-based reaction screening is utilized as a tool for the objective comparison of reaction conditions as demonstrated in four case studies. This contributes to an understanding of factors limiting a reaction's FG tolerance and the identification of truly mild reactions.
Oxidative decarboxylative radical trifluoromethylthiolation of alkyl carboxylic acids with silver(i) trifluoromethanethiolate and selectfluor
He, Bin,Xiao, Zhiwei,Wu, Hao,Guo, Yong,Chen, Qing-Yun,Liu, Chao
, p. 880 - 883 (2017/01/13)
A straightforward silver-mediated oxidative decarboxylative radical trifluoromethylthiolation reaction of aliphatic carboxylic acid is described. This reaction operates under mild conditions and allows the synthesis of various valuable alkyltrifluoromethylthioethers from abundant alkyl carboxylic acids and convenient nucleophilic AgSCF3 reagent. It provides a practical and efficient approach for the preparation of alkyltrifluoromethylthioethers.