64839-09-4

Upstream product

• 91796-44-0 Benzyl 3-(phenylmethoxy)-2-methylpropanoate 
• 2163-42-0 2-methyl-1.3-propanediol 
• 100-39-0 benzyl bromide 
• 124755-27-7 (E)-(2R,5R,6S)-7-<(tert-butyldimethylsilyl)oxy>-2,4,6-trimethyl-3-heptene-1,5-diol 
• 126308-98-3 4-(3-Benzyloxy-2-methyl-propoxymethyl)-1,2-dimethoxy-benzene 
• 126309-00-0 4-(3-Benzyloxy-2-methyl-propoxymethyl)-1,5-dimethoxy-naphthalene 
• 3587-60-8 Benzyloxymethyl chloride 
• 191105-59-6 (S)-N-propionyl-4-(4-hydroxybenzyl)oxazolidin-2-one 
• 27942-89-8 5-methyl-2-phenyl-[1,3]dioxane 
• 100-52-7 benzaldehyde 
• 5658-46-8 ((2-methylallyloxy)methyl)benzene 
• 59965-24-1 (+/-)-methyl 2-methyl-3-(phenylmethoxy)propanoate 
• 139017-28-0 1-(3-Benzyloxy-2-methyl-propyl)-1-phenyl-silolane 

Downstream Products

• 64316-89-8 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 3-benzyloxy-2-methyl-propyl ester 
• 74130-31-7 3-(benzyloxy)-2-methylpropanal 
• 63930-49-4 (R)-3-(benzyloxy)-2-methylpropan-1-ol 
• 63930-46-1 (S)-3-benzyloxy-2-methylpropan-1-ol 
• 141885-91-8 (S)-3-benzyloxy-2-methylpropyl acetate 
• 141885-91-8 (R)-3-benzyloxy-2-methylpropyl acetate 
• 96556-45-5 3-(benzyloxy)-2-methylpropyl p-toluenesulfonate 
• 16897-88-4 (2RS,3SR)-4-benzyloxy-3-methyl-2-butanol 
• 87702-54-3 (S)-3-((2R,3S)-5-Benzyloxy-3-hydroxy-2,4-dimethyl-pentanoyl)-4-isopropyl-oxazolidin-2-one 
• 87758-66-5 (2S,3R,4R)-5-Benzyloxy-3-hydroxy-2,4-dimethyl-pentanoic acid methyl ester 
• 87702-55-4 (±)-methyl (2S,3S,4S)-5-(benzyloxy)-3-hydroxy-2,4-dimethylpentanoate 
• 91273-58-4 3-benzyloxy-2-methyl-1-propyl bromide 
• 1246458-50-3 t-butyl 4-(3-benzyloxy-2-methylpropoxy)benzylcarbamate 
• 1380304-53-9 3-(benzyloxy)-2-methylpropyl methanesulfonate 

Relevant academic research and scientific papers

6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS

The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE

The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.

Substituted heteroaryl compound and composition thereof, and uses of substituted heteroaryl compound and composition thereof

The present invention provides a substituted heteroaryl compound and a composition thereof, and uses of the substituted heteroaryl compound and the composition, wherein the compound is a compound represented by a formula (I) or a stereoisomer, a tautomer, a nitrogen oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug of the compound represented by the formula (I). The present invention further provides a pharmaceutical composition containing the compound, wherein the pharmaceutical composition can regulate activity of protein kinases, particularly Aurora kinases and JAK kinases, and can be used for prevention, treatment, therapy and alleviation of protein kinases, particularly Aurora kinases and JAK kinase activity mediated diseases or disorders.

DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME

The present invention provides a compound having an excellent efficacy for controlling weeds. A dihydropyrone compound of formula (I): wherein m is 1, 2 or 3; n is an integer of any one of 1 to 5; X represents O, S, S(O) or S(O)2; R1 /sup

N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS

Disclosed herein are substantially pure forms of the compounds of Formula (I), (II), (III), (IV) and (V), or a pharmaceutically acceptable salt, prodrug, hydrate, solvate, polymorph, stereoisomer or ester thereof. Also disclosed are methods of inhibiting an activity of a serotonin receptor, methods inhibiting an activation of a serotonin receptor, and methods of alleviating or treating various disease conditions and side effects.

Total synthesis of (-)-baconipyrone C

A highly stereoselective asymmetric total synthesis of marine polypropionate (-)-baconipyrone C has been achieved. Utilization of desymmetrization technique to create five stereogenic centres, Sharpless epoxidation, Gilman's reaction and resolution of met

PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER’S DISEASE

Compounds of formula (I) are modulators of gamma-secretase, and hence are useful in treatment of Alzheimer’s disease.

Chemoenzymatic Approach toward the Pure Enantiomers of 2-Methyl-1,3-propanediol Mono(p-Methoxybenzyl Ether)

In a route towards the enantiomerically pure 2-methylpropane-1,3-diol mono(p-methoxybenzyl ether), which is an important starting material for natural product synthesis, a kinetic resolution approach by means of lipase-catalyzed hydrolysis as well as acyl

A new and general synthesis of chiral β-ketosulfoxides by reaction of (+)-(R)-methyl p-tolyl sulfoxide with nitriles

The nitrile functional group is efficiently transformed into the β-ketosulfoxide moiety by reaction with the anion formed from (+)-(R)-methyl p-tolyl sulfoxide and aqueous acidic work-up of the reaction.

Microwave thermolysis IV: Selective deprotection of MPM ethers using clay supported ammonium nitrate 'clayan' in dry media

Selective deprotection of (4-methoxyphenyl)-methyl (MPM) ethers using clay supported ammonium nitrate under microwave irradiation is described. The use of expensive reagents and problems associated with slurry reactions are avoided.