6526-66-5

Basic information

• Product Name: 2-AMINO-N,N-DIMETHYL-BENZAMIDE
• Synonyms: BUTTPARK 34\02-08;2-AMINO-N,N-DIMETHYL-BENZAMIDE;AKOS BBB/070;2-amino-N,N-dimethylbenzamide(SALTDATA: HCl);N,N-Dimethyl-2-aminobenzamide;o-Amino-N,N-dimethylbenzamide
• CAS NO: 6526-66-5
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.20438
• Mol File: 6526-66-5.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 332.3°C at 760 mmHg
• Flash Point: 154.8°C
• Appearance: /
• Density: 1.116g/cm³
• Vapor Pressure: 0.000147mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-AMINO-N,N-DIMETHYL-BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N,N-DIMETHYL-BENZAMIDE(6526-66-5)
• EPA Substance Registry System: 2-AMINO-N,N-DIMETHYL-BENZAMIDE(6526-66-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 6526-66-5(Hazardous Substances Data)

Usage

General Description

2-AMINO-N,N-DIMETHYL-BENZAMIDE is a chemical compound that belongs to the benzamide family. It is a derivative of benzene with an amino group and dimethyl substituents attached to the amide functional group. 2-AMINO-N,N-DIMETHYL-BENZAMIDE has various industrial and laboratory applications, including use as a building block in the synthesis of pharmaceuticals and organic compounds. It is also used in research and development to study its properties and potential medical and industrial applications. 2-AMINO-N,N-DIMETHYL-BENZAMIDE is a white crystalline solid at room temperature and is soluble in organic solvents, making it useful for various chemical reactions and applications.

InChI:InChI=1/C9H12N2O/c1-11(2)9(12)7-5-3-4-6-8(7)10/h3-6H,10H2,1-2H3

Upstream product

• 5344-90-1 2-Aminobenzyl alcohol 
• 68-12-2 N,N-dimethyl-formamide 
• 118-92-3 anthranilic acid 
• 1608-26-0 Hexamethylphosphorous triamide 
• 118-48-9 isatoic anhydride 
• 124-40-3 dimethyl amine 
• 610-14-0 2-nitrobenzyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 
• 101-42-8 fenuron 
• 2018-71-5 N,N-dimethyl-2-nitrobenzamide 
• 3585-33-9 lithium dimethylamide 
• 134-20-3 2-carbomethoxyaniline 
• 21563-73-5 2-aminobenzoyl chloride 

Downstream Products

• 178672-27-0 2-trifluoroacetylamino-N,N-dimethylbenzamide 
• 65000-22-8 N-(methoxymethyl)-N-methylbenzamide 
• 1155498-86-4 2-(2-chloroacetamido)-N,N-dimethylbenzamide 
• 1341200-49-4 N,N-dimethyl-2-((2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)benzamide 
• 1341200-74-5 2-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N,N-dimethylbenzamide 
• 1341200-46-1 2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,N-dimethylbenzamide 
• 1246547-22-7 N,N-dimethyl-2-((4-methylpyridin-3-yl)amino)benzamide 
• 1042434-80-9 2-((2,5-dichloropyrimidin-4-yl)amino)-N,N-dimethylbenzamide 
• 220383-14-2 1-[N-(2-dimethylaminocarbonylphenyl)-2-aminoethyl]-4-(2-methoxyphenyl)-piperazine 
• 114559-89-6 N,N-Dimethyl-2-[3-((1R,3R,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-ureido]-benzamide 
• 193974-95-7 2-Acryloylamino-N,N-dimethyl-benzamide 
• 109072-14-2 2-Isopropylideneamino-N,N-dimethyl-benzamide 

Relevant articles and documents

P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds

A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. P(NMe2)3 revealed the maximum efficacies under the aerobic reaction conditions and a spectrum of bis-nucleophiles, and isothiocyanates were tolerated well to serve the access of manifold immense molecules. (Figure presented.).

Aromatic heterocycle-containing 2, 4-diarylaminopyrimidine derivative as well as preparation and application of 2, 4-diarylaminopyrimidine derivative

The invention relates to an aromatic heterocycle-containing 2, 4-diarylaminopyrimidine derivative represented by a general formula I, an optical isomer, a pharmaceutically acceptable salt, a solvate or a prodrug thereof, preparation methods of the aromatic heterocycle-containing 2, 4-diarylaminopyrimidine derivative and the optical isomer, the pharmaceutically acceptable salt, the solvate or the prodrug, and a pharmaceutical composition using the compound represented by the general formula I as an active component, wherein substituents R1, R2, R3, R4, R5, R6, X, Y and Z have meanings given inthe specification. The invention also relates to the compound shown in the general formula I, which has strong ALK and ROS1 kinase inhibition effects, and also relates to application of the compound and the optical isomer and pharmaceutically acceptable salt thereof in preparation of drugs for treatment and/or prevention of diseases caused by ALK and ROS1 abnormal expression, and application of the compound in preparation of drugs for prevention of diseases caused by ALK and ROS1 abnormal expression. Use in particular in the preparation of a medicament for treatment and/or for preventing cancer

Visible-light photocatalytic α-amino C(sp3)–H activation through radical translocation: a novel and metal-free approach to α-alkoxybenzamides

Visible-light photocatalytic, metal-free synthesis of valuable α-alkoxybenzamides starting with readily prepared o-aminobenzamides and alcohols through radical translocation under mild conditions is reported. This protocol employs eosin Y as an organophot