65405-67-6

Basic information

• Product Name: 4'methoxy-2-methylcinnamaldehyde
• Synonyms: 4'methoxy-2-methylcinnamaldehyde;2-Propenal, 3-(4-methoxyphenyl)-2-methyl-;ALPHA-METHYLPARA-METHOXYCINNAMICALDEHYDE;ALPHA-METHYL-4-METHOXYCINNAMALDEHYDE;PARA-METHOXY-METHYLCINNAMALDEHYDE;ALPHA-METHYL-PARA-METHOXYCINNAMALDEHYDE;3-(4-methoxyphenyl)-2-methyl-2-Propenal;alpha.-Methyl p-methoxy cinnamic aldehyde
• CAS NO: 65405-67-6
• Molecular Formula: C₁₁H₁₂O₂
• Molecular Weight: 176.2118
• EINECS: 265-737-4
• Mol File: 65405-67-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 108 °C(Press: 0.1 Torr)
• Appearance: /
• Density: 1.1265 g/cm3
• CAS DataBase Reference: 4'methoxy-2-methylcinnamaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4'methoxy-2-methylcinnamaldehyde(65405-67-6)
• EPA Substance Registry System: 4'methoxy-2-methylcinnamaldehyde(65405-67-6)

Safety Data

• Hazardous Substances Data: 65405-67-6(Hazardous Substances Data)

Usage

Description

May be prepared by formulation of the corresponding olefin.

Preparation

By formylation of the corresponding olefin.

Upstream product

• 100-66-3 methoxybenzene 
• 78-84-2 isobutyraldehyde 
• 25679-28-1 cis-Anethole 
• 68-12-2 N,N-dimethyl-formamide 
• 14674-38-5 N-(4-methoxybenzylidene)-p-toluenesulfonamide 
• 107-18-6 allyl alcohol 
• 139711-00-5 1-(4-methoxyphenyl)-2-methyl-2-propen-1-ol 
• 139710-95-5 1-(p-methoxyphenyl)-1,2-dibromo-2-methylpropane 
• 877-99-6 1-methoxy-4-(2-methyl-1-propenyl)benzene 
• 139711-01-6 (Z)-3-(4-Methoxy-phenyl)-2-methyl-prop-2-en-1-ol 
• 123-11-5 4-methoxy-benzaldehyde 
• 123-38-6 propionaldehyde 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 

Downstream Products

• 1589518-75-1 N-(6-methoxy-2-methyl-1H-inden-1-yl)-4-methylbenzenesulfonamide 
• 1564277-31-1 N-(2-(4-methoxyphenyl)-3-methyl-5-oxo-5,6,7,8-tetrahydroquinolin-1(2H)-yl)benzamide 
• 1564277-26-4 2-(4-methoxyphenyl)-3-methyl-1-(phenylamino)-1,2,7,8-tetrahydroquinolin-5(6H)-one 
• 1491166-58-5 C₂₃H₂₂O₃ 
• 1491166-55-2 C₁₇H₁₈O₃ 
• 1449584-19-3 2-(4-methoxyphenyl)-3-methyl-7,7-diphenyl-7,8-dihydropyrano[4,3-b]pyran-5(2H)-one 
• 1491165-78-6 C₂₄H₂₄O₆ 
• 1491165-71-9 C₂₂H₁₉FO₄ 
• 1491165-76-4 C₂₃H₂₂O₅ 

Relevant articles and documents

Synthesis method of cinnamyl aldehyde compound

The invention discloses a synthesis method of a cinnamyl aldehyde compound. The cinnamyl aldehyde compound is synthesized through the crossed dehydrogenation coupling reaction with fatty aldehyde andsbstituted sromatic hydrocarbon as the initial raw materials and palladium chloride and amino acid as the catalysts. Compared with a traditional cinnamyl aldehyde compound synthesis method, the methodis simple in operation, mild in reaction condition, low in applied reagent price, high in efficiency and high in atom utilization rate.

Poly(phosphoric acid) (PPA)-Promoted 5- exo -Cyclization of Iminium Ions Generated in Situ: A Facile Access to Functionalized Indene Derivatives

A metal-free Bronsted acid promoted two-component reaction between cinnamaldehydes and sulfonamides is described. This cascade process provides a simple and atom-economical alternative synthesis of a range of functionalized indenes from easily available starting materials. The resulting N -indenylsulfonamides were readily converted into the corresponding indenylenamines or indanones.

Use of n-substituted (3,6-dihydro)-2h-1,2-oxazine derivatives as selective mglur1 antagonists

STR1Use of a compound of formula (I) in which, R 1, R 2 and R 3 are independently hydrogen, (C 1 -C 6)alkyl, (C 2 -C 6)alkenyl, C 3 -C 10)cycloalkyl, unsubstituted or substituted aryl, unsubstituted or substituted aryl(C 1 -C 6)alkyl, unsubstituted or substituted aryl(C 2 -C 6)alkenyl, halo, carboxy, (C 1 -C 6)alkoxycarbonyl or --(CH 2) m --OH wherein m is 1, 2 or 3; - - - indicates a single or a double bond; X and each independently hydrogen, or X and Y together represent a bridge of the formula --CH 2) m --, where n is 1 or 2; A 1 and A 2 are each independently an unsubstituted or substituted aryl; Z is --CO--, --SO 2 -- or --CH 2 ; provided that, when Z is --CO--, A 1 is not 3,4,5-trimethoxyphenyl; or a pharmaceutically-acceptable salt or ester thereof, for the manufacture of a medicament for the treatment of a condition indicating the administration of a selective mGluR1 antagonist.