658-14-0

Usage

General Description

1-Fluoro-4-(methylsulfinyl)benzene is a chemical compound with the molecular formula C7H7FS. It is an aromatic compound with a single fluorine atom and a methylsulfinyl group attached to a benzene ring. 1-Fluoro-4-(methylsulfinyl)benzene is commonly used in organic synthesis and as a building block in the production of pharmaceuticals and agrochemicals. It has also been studied for its potential applications in materials science and as a precursor for the synthesis of other fluorinated compounds. 1-Fluoro-4-(methylsulfinyl)benzene is a versatile and useful chemical compound with a wide range of potential industrial applications.

Upstream product

• 371-15-3 p-fluorothioanisole 
• 100-68-5 methyl-phenyl-thioether 
• 3996-46-1 p-FC₆H₄SOCH₂COOH 
• 164021-74-3 (1S,2R)-(-)-2-[N-(3’,5’-di-tert-butylsalicylidene)amino]-1,2-diphenylethanol 
• 371-42-6 4-Fluorothiophenol 
• 67-68-5 dimethyl sulfoxide 
• 332-51-4 (4-fluorophenylthio)acetic acid 

Downstream Products

• 455-15-2 1-(methylsufonyl)-4-fluorobenzene 
• 371-15-3 p-fluorothioanisole 
• 635311-89-6 (4-fluorophenyl)(imino)(methyl)-λ⁶-sulfanone 
• 1426131-98-7 1-(tert-butyl)-4-(((4-fluorophenyl)sulfinyl)methyl)benzene 
• 658-14-0 R-(-)-4-fluoro phenyl methyl sulfoxide 
• 175911-67-8 S-(+)-4-fluoro phenyl methyl sulfoxide 
• 226396-70-9 (4-fluoro-phenylsulfanyl)-acetic acid methyl ester 
• 39547-79-0 1-fluoro-4-((fluoromethyl)sulfonyl)benzene 
• 635311-90-9 C₄₇H₈₂FNO₃SSi₃ 
• 635311-88-5 C₁₃H₂₂FNOSSi 

Relevant academic research and scientific papers

Visible light-promoted selective oxidation of sulfides to sulfoxides catalyzed by ruthenium porphyrins with iodobenzene diacetate

Under visible light irradiation, the carbonyl ruthenium(II) porphyrin complexes efficiently catalyze the selective oxidation of sulfides to sulfoxides with iodobenzene diacetate [PhI(OAc)2] as the oxygen source. Various thioanisoles and allylic

Spectroscopic characterization and reactivity studies of a mononuclear nonheme Mn(III)-hydroperoxo complex

We report the first example of a mononuclear nonheme manganese(III)- hydroperoxo complex derived from protonation of an isolated manganese(III)- peroxo complex bearing an N-tetramethylated cyclam (TMC) ligand, [Mn III(TMC)(OOH)]2+. T

VpStyA1/VpStyA2B of variovorax paradoxus EPS: An aryl alkyl sulfoxidase rather than a styrene epoxidizing monooxygenase

Herein we describe the first representative of an E2-type two-component styrene monooxygenase of proteobacteria. It comprises a single epoxidase protein (VpStyA1) and a two domain protein (VpStyA2B) harboring an epoxidase (A2) and a FAD-reductase (B) doma

Aerobic oxidation of sulfides to sulfoxides catalyzed by gold/manganese oxides

Although selective oxidation of sulfides to sulfoxides with molecular oxygen is a difficult reaction due to the overoxidation to sulfone, manganese oxides were found to catalyze the aerobic oxidation of sulfides to sulfoxides in 1,2- dichlorobenzene at 10

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.

COVALENT ORGANIC FRAMEWORKS AND APPLICATIONS AS PHOTOCATALYSTS

Described herein are covalent organic frameworks. The covalent organic frameworks have unique structural and physical properties, which lends them to be versatile in a number of different applications and uses. In one aspect, the covalent organic frameworks are composed of a plurality of fused aromatic groups and electron-deficient chromophores. The covalent organic frameworks are useful as photocatalysts in a number of different applications.

Catalyst-free visible light-mediated selective oxidation of sulfides into sulfoxides under clean conditions

A facile and efficient visible-light-mediated method for directly converting sulfides into sulfoxides under clean conditions without using any photocatalysts is reported. This method exhibited favourable compatibility with functional groups and afforded a series of sulfoxides with high selectivity and yields. Moreover, in order to shed more light on such a transformation, detailed mechanism studies were carried out both experimentally and theoretically. The readily accessible, low-cost and eco-friendly nature of the developed method will endow it with attractive applications in chemical synthesis.

Synergistic cooperative effect of CF3SO2Na and bis(2-butoxyethyl)ether towards selective oxygenation of sulfides with molecular oxygen under visible-light irradiation

A safe, practical and eco-friendly method for the switchable synthesis of sulfoxides and sulfones through visible-light-initiated oxygenation of sulfides at ambient temperature under transition-metal-, additives-free and minimal solvent conditions. The synergistic catalytic efforts between CF3SO2Na and 2-butoxyethyl ether represents the key promoting factor for the reaction. This journal is

Flow Electrosynthesis of Sulfoxides, Sulfones, and Sulfoximines without Supporting Electrolytes

An efficient electrochemical flow process for the selective oxidation of sulfides to sulfoxides and sulfones and of sulfoxides toN-cyanosulfoximines has been developed. In total, 69 examples of sulfoxides, sulfones, andN-cyanosulfoximines have been synthesized in good to excellent yields and with high current efficiencies. The synthesis was assisted and facilitated through a supporting electrolyte-free, fully automated electrochemical protocol that highlights the advantages of flow electrolysis.

Sulfoxide and Sulfone Synthesis via Electrochemical Oxidation of Sulfides

The oxidation of diaryl sulfides and aryl alkyl sulfides to the corresponding sulfoxides and sulfones under electrochemical conditions is reported. Sulfoxides are selectively obtained in good yield under a constant current of 5 mA for 10 h in DMF, while sulfones are formed as the major product under a constant current of 10 or 20 mA for 10 h in MeOH. The oxygen of both the sulfoxide and sulfone function is derived from water.