66049-39-6Relevant academic research and scientific papers
Effective synthesis of novel dihydrobenzisoxazoles bearing the 2-aminothiazole moiety and evaluation of the antiproliferative activity of their acylated derivatives
Khlebnicova, Tatyana S.,Lakhvich, Fedor A.,Matous, Anton E.,Piven, Yuri A.,Scherbakov, Alexander M.,Shchegolev, Yuri Yu.,Sorokin, Danila V.,Yastrebova, Margarita A.,Zinovich, Veronica G.
supporting information, p. 10432 - 10443 (2021/12/17)
An effective method for the synthesis of 8-aryl-4,5-dihydrothiazolo[4′,5′:3,4]benzo[1,2-c]isoxazol-2-amines was developed. This method includes the α-keto bromination of 3-aryl-6,7-dihydrobenzo[c]isoxazol-4(5H)-ones followed by the condensation of the obt
Direct oxidative esterification of toluene with 1,3-dicarbonyl compounds catalysed by copper complex supported on magnetic nanoparticles
Azizi, Kobra,Esfandiary, Naghmeh,Karimi, Meghdad,Kazemi, Maryam,Heydari, Akbar
, (2017/07/25)
Toluene oxidation is one of the substantial industrial technologies since oxidized products are industrially very important intermediates. A Fe3O4@cysteine@Cu-catalysed reaction that uses tert-butyl hydroperoxide as oxidant to produce esters from toluene and β-diketones or β-keto esters, enolate precursors, has been developed. Oxidative esterification of toluene with 1,3-dicarbonyl derivatives led to C─O bond formation and direct C─H functionalization.
Synthesis of β-dicarbonyl compounds using 1-acylbenzotriazoles as regioselective C-acylating reagents
Katritzky, Alan R.,Pastor, Alfredo
, p. 3679 - 3681 (2007/10/03)
1-Acylbenzotriazoles 1 are efficient C-acylation reagents for the regioselective conversion of ketone enolates 2 into β-diketones 3.
SAR studies of 2-o-substituted-benzoyl- and 2-alkanoyl-cyclohexane-1,3-diones as inhibitors of 4-hydroxyphenylpyruvate dioxygenase
Lin, Yung-Lung,Wu, Chung-Shieh,Lin, Shean-Woei,Yang, Ding-Yah
, p. 843 - 845 (2007/10/03)
Inhibition studies of 4-hydroxyphenylpyruvate dioxygenase (HPPD) with various synthesized 2-o-substituted-benzoyl- and 2-alkanoyl-cyclohexane-1,3-diones suggest that the presence of a strongly electronegative group at the ortho position and the conformati
Discovery of a potent, non-triketone type inhibitor of 4-hydroxyphenylpyruvate dioxygenase
Lin, Shean-Woei,Lin, Yun-Loung,Lin, Tzu-Ching,Yang, Ding-Yah
, p. 1297 - 1298 (2007/10/03)
3-Cyclopropanecarbonyloxy-2-cyclohexen-1-one has been found to be a new, potent, low molecular weight non-triketone type inhibitor of 4-hydroxyphenylpyruvate dioxygenase with IC50 value of 30 nM. Preliminary studies suggest that the two carbonyl groups present in the compound are crucial for the inhibition activity. (C) 2000 Elsevier Science Ltd. All rights reserved.
2-Chloro-1,3-dimethylimidazolinium chloride. 1. A powerful dehydrating equivalent to DCC
Isobe, Toshio,Ishikawa, Tsutomu
, p. 6984 - 6988 (2007/10/03)
2-Chloro-1,3-dimethylimidazolinium chloride (DMC) (3) can act as a powerful dehydrating agent, replacing DCC (1) under nearly neutral conditions. Its application to acylation and dehydration is described.
SYNTHESIS OF ENOL ESTERS AND ENOL LACTONES VIA PALLADIUM-CATALYZED CARBONYLATION OF ARYL AND ALKENYL HALIDES
Shimoyama, Izumi,Zhang, Yantao,Wu, Guangzhong,Negishi, Ei-ichi
, p. 2841 - 2844 (2007/10/02)
Acylpalladium species derivable via oxidative addition of a Pd-phosphine complex with aryl and alkenyl iodides and CO insertion can react, either intramolecularly or intermolecularly, with enolates generated in situ to give the corresponding enol esters a
Synthesis and Photocyclization of 2-Aroyl-3-methylcyclohex-2-enones
Tamura, Yasumitsu,Wada, Akimori,Okuyama, Shigehiro,Fukumori, Satoshi,Hayashi, Yoko,et al.
, p. 1312 - 1320 (2007/10/02)
Preparation and photocyclization of a number of 2-aroyl-3-methylcyclohex-2-enones have been investigated.Irradiation of these systems resulted in a photo-enolization followed by a pericyclic reaction to give 3,4-dihydroanthracen-1(2H)-ones.Keywords - prep
