6622-09-9

Basic information

• Product Name: [(benzylsulfanyl)(phenyl)methyl]benzene
• CAS NO: 6622-09-9
• Molecular Formula: C₂₀H₁₈S
• Molecular Weight: 290.4219
• Mol File: 6622-09-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 410°C at 760 mmHg
• Flash Point: 193.8°C
• Density: 1.113g/cm³
• Vapor Pressure: 1.48E-06mmHg at 25°C
• Refractive Index: 1.629
• CAS DataBase Reference: [(benzylsulfanyl)(phenyl)methyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: [(benzylsulfanyl)(phenyl)methyl]benzene(6622-09-9)
• EPA Substance Registry System: [(benzylsulfanyl)(phenyl)methyl]benzene(6622-09-9)

Safety Data

• Hazardous Substances Data: 6622-09-9(Hazardous Substances Data)

Usage

General Description

[(benzylsulfanyl)(phenyl)methyl]benzene, also known as diphenyl(methylthio)methylbenzene, is an organic compound with the chemical formula C20H18S. It is a colorless aromatic liquid that is commonly used as a solvent in various industries. [(benzylsulfanyl)(phenyl)methyl]benzene is derived from benzene and consists of a benzylsulfanyl group attached to a phenylmethyl group, which is further attached to another benzene ring. It has a strong aromatic odor and is known for its ability to dissolve a wide range of organic compounds. [(benzylsulfanyl)(phenyl)methyl]benzene is used as an intermediate in the production of various chemicals and pharmaceuticals, as well as in the synthesis of fragrances and flavors. It is also used as a reagent in organic chemical reactions.

Upstream product

• 100-53-8 phenylmethanethiol 
• 90-99-3 diphenylchloromethane 
• 776-74-9 Bromodiphenylmethane 
• 908093-98-1 diazodiphenylmethane 
• 6317-10-8 2,2-diphenyl-1,3-dithiolane 
• 100-39-0 benzyl bromide 
• 1589-82-8 phenylmagnesium bromide 
• 1450-31-3 Thiobenzophenon 
• 91-01-0 1,1-Diphenylmethanol 
• 853-83-8 N-tosyldiphenylmethylamine 

Downstream Products

• 13641-03-7 ((benzylsulfinyl)methylene)dibenzene 
• 150-60-7 dibenzyl disulphide 
• 102751-83-7 ((2,4,6-trimethoxyphenyl)methylene)dibenzene 

Relevant articles and documents

Visible-Light-Triggered C-C and C-N Bond Formation by C-S Bond Cleavage of Benzylic Thioethers

The cleavage of sulfidic C-S bonds under visible-light irradiation was harnessed to generate carbocations under neutral conditions and synthesize valuable di- and triarylalkanes as well as benzyl amines. To this end, photoredox catalysis and direct photoinduced C-S bond cleavage are used as complementary approaches and participate in the versatility of the general strategy. Extensive mechanistic studies have demonstrated the diversity of the reaction mechanism at work in these different reactions.

Selective synthesis of thioethers in the presence of a transition-metal-free solid Lewis acid

The synthesis of thioethers starting from alcohols and thiols in the presence of amorphous solid acid catalysts is reported. A silica alumina catalyst with a very low content in alumina gave excellent results in terms of both activity and selectivity also under solvent-free conditions. The reaction rate follows the electron density of the carbinol atom in the substrate alcohol and yields up to 99% and can be obtained for a wide range of substrates under mild reaction conditions.

Selective benzylic and allylic alkylation of protic nucleophiles with sulfonamides through double Lewis acid catalyzed cleavage of sp3 carbon-nitrogen bonds

The acid-catalyzed benzylic and allylic alkylation of protic nucleophiles is fundamentally important for the formation of carbon-carbon and carbon-heteroatom bonds, and it is a formidable challenge for benzylic and allylic amine derivatives to be used as the alkylating agents. Herein we report a highly efficient benzylic and allylic alkylation of protic carbon and sulfur nucleophiles with sulfonamides through double Lewis acid catalyzed cleavage of sp3 carbon-nitrogen bonds at room temperature. In the presence of a catalytic amount of inexpensive ZnCl2-TMSCl (TMSCl: chlorotrimethylsilane), 1,3-diketones, β-keto esters, β-keto amides, malononitrile, aromatic compounds, thiols, and thioacetic acid can couple with a broad range of tosylactivated benzylic and allylic amines to give diversely functionalized products in good to excellent yields and with high regioselectivity. Furthermore, the cross-coupling reaction of 1,3-dicarbonyl compounds with benzylic propargylic amine derivatives has been successfully applied to the one-step synthesis of polysubstituted furans and benzofurans.